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Product Details
PA5-32692
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 20 amino acid peptide from internal region of human CCKAR.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550155
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (90%); Elephant (85%); Rat, Panda, Guinea pig (80%).
Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.
Target Information
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCK-A receptor; CCK-AR; CCK1-R; ccka receptor; Cholecystokinin receptor type A; cholecystokinin type-A receptor; Cholecystokinin-1 receptor; HGNC:1570
Gene Aliases: CCK-A; CCK1-R; CCK1R; CCKAR; CCKRA
UniProt ID: (Human) P32238
Entrez Gene ID: (Human) 886
temperature homeostasis
gastric acid secretion
neuron migration
reduction of food intake in response to dietary excess
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
axonogenesis
response to nutrient
digestion
feeding behavior
response to radiation
response to heat
insulin secretion
pancreatic juice secretion
forebrain development
pancreas development
organ regeneration
actin cytoskeleton reorganization
response to lipopolysaccharide
cellular response to hormone stimulus
cholecystokinin signaling pathway
response to starvation
regulation of potassium ion transport
regulation of hormone secretion
response to glucocorticoid
regulation of calcium ion transport
positive regulation of somatostatin secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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