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Product Details
MA5-43065
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
015
Immunogen
Recombinant Human CCL14 Protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2912205
Product Specific Information
Specificity: Human CCL14
Target Information
This gene, CCL14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. This gene expresses both monocistronic and bicistronic transcripts. Bicistronic transcripts include the upstream cytokine gene CCL15. In addition, CCL14 undergoes alternative splicing in the bicistronic transcripts; it is unknown if its monocistronic transcript is also subject to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-C motif chemokine 14; chemokine (C-C motif) ligand 14; Chemokine CC-1/CC-3; chemokine CC-3; H HCC-1(1-74); HCC-1(1-74); HCC-1/HCC-3; hemofiltrate CC chemokine 1; NCC-2; new CC chemokine 2; small inducible cytokine subfamily A (Cys-Cys), member 14; Small-inducible cytokine A14
Gene Aliases: CC-1; CC-3; CCL14; CKB1; HCC-1; HCC-1(1-74); HCC-1/HCC-3; HCC-3; MCIF; NCC-2; NCC2; SCYA14; SCYL2; SY14
UniProt ID: (Human) Q16627
Entrez Gene ID: (Human) 6358
monocyte chemotaxis
cellular calcium ion homeostasis
inflammatory response
G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
neutrophil chemotaxis
positive regulation of GTPase activity
lymphocyte chemotaxis
positive regulation of inflammatory response
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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