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Invitrogen
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Immunogen sequence: DYSDRTISDE DESDEDMFMK FVSEDLHRCA LLTADSFGDP FFPRTTQILL EYQLGRWVPR LREPRDLYGV SSSGPLSPTR WPYHCEVIDE
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 90%.
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP/GTP binding protein-like 3; ATP/GTP-binding protein-like 3; CBCP3; Cytosolic carboxypeptidase 3; Protein deglutamylase CCP3
Gene Aliases: AGBL3; CCP3
UniProt ID: (Human) Q8NEM8
Entrez Gene ID: (Human) 340351
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