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FIGURE: 1 / 2
Positive control: HCT116 cell lysate, A549 cell lysate, Hela cell lysate, THP-1 cell lysate, SW480 cell lysate, HEK-293 cell lysate, SW480.
Predicted band size: 87 kDa
Subcellular Location: Cytoplasmic granule membrane.
Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42. May be involved in cell cycle regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell cycle progression protein 1; Cell cycle progression restoration protein 8
Gene Aliases: CCP8; CCPG1; CPR8; KIAA1254
UniProt ID: (Human) Q9ULG6
Entrez Gene ID: (Human) 9236
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