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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD11c Antibodies

          Invitrogen

          CD11c Polyclonal Antibody

          2 References
          View all (105) CD11c antibodies

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          Cite CD11c Polyclonal Antibody

          • Antibody Testing Data (2)
          CD11c Antibody in Immunocytochemistry (ICC/IF)
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          CD11c Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          CD11c Antibody (PA5-90208) in ICC/IF

          Immunofluorescence analysis of CD11c in THP-1 cells. Samples were incubated with CD11c Polyclonal antibody (Product # PA5-90208) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CD11c Antibody in Immunocytochemistry (ICC/IF)
          CD11c Antibody in Western Blot (WB)

          Product Details

          PA5-90208

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          -
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          View 1 publication 1 publication

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 146-342 of ITGAX (NP_0008782)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.68 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2805960

          Product Specific Information

          Immunogen sequence: PRQEQDIVFL IDGSGSISSR NFATMMNFVR AVISQFQRPS TQFSLMQFSN KFQTHFTFEE FRRSSNPLSL LASVHQLQGF TYTATAIQNV VHRLFHASYG ARRDAAKILI VITDGKKEGD SLDYKDVIPM ADAAGIIRYA IGVGLAFQNR NSWKELNDIA SKPSQEHIFK VEDFDALKDI QNQLKEKIFA IEGTETT

          Positive Samples: THP-1, Mouse small intestine, Mouse spleen; Cellular Location: Membrane, Single-pass type I membrane protein

          Target Information

          CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; integrin alpha X; Integrin alpha-X; integrin aX; integrin, alpha X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Leu M5; leu M5, alpha subunit; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain

          View more View less

          Gene Aliases: AI449405; CD11C; Cr4; ITGAX; N418; RGD1561123; SLEB6

          View more View less

          UniProt ID: (Human) P20702, (Mouse) Q9QXH4

          View more View less

          Entrez Gene ID: (Human) 3687, (Mouse) 16411, (Rat) 499271

          View more View less

          Function(s)
          receptor activity protein binding metal ion binding
          Process(es)
          cell adhesion integrin-mediated signaling pathway heterotypic cell-cell adhesion activated T cell proliferation defense response to virus positive regulation of protein targeting to mitochondrion organ morphogenesis extracellular matrix organization leukocyte migration
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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