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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD11c Antibodies

          Invitrogen

          CD11c Chimeric Recombinant Rabbit Monoclonal Antibody (N418)

          View all (154) CD11c antibodies

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          Cite CD11c Chimeric Recombinant Rabbit Monoclonal Antibody (N418)

          • Antibody Testing Data (1)
          CD11c Chimeric Antibody in Immunocytochemistry (ICC/IF)
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          CD11c Chimeric Antibody in Immunocytochemistry (ICC/IF)
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          CD11c Chimeric Antibody (MA5-47951) in ICC/IF

          Immunocytochemistry/Immunofluorescence analysis of CD11c in U937 cells using CD11c Chimeric Monoclonal Antibody (Product # MA5-47951). Paraformaldehyde-fixed cells were immobilized on cover slips and stained with CD11c Chimeric Monoclonal Antibody at 10 µg/mL for 1h followed by Alexa Fluor488 secondary antibody (1 µg/mL), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-rig... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CD11c Chimeric Antibody in Immunocytochemistry (ICC/IF)

          Product Details

          MA5-47951

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          10 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG, kappa

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          N418

          Immunogen

          Hamster spleen cells that had been primed to mouse spleen dendritic cells.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS

          Contains

          0.02% ProClin 300

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3074395

          Product Specific Information

          Specificity: The antibody binds to mouse and human CD11c.

          Target Information

          CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; integrin alpha X; Integrin alpha-X; integrin aX; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Leu M5; leu M5, alpha subunit; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain

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          Gene Aliases: AI449405; CD11C; Cr4; ITGAX; N418; SLEB6

          View more View less

          UniProt ID: (Human) P20702, (Mouse) Q9QXH4

          View more View less

          Entrez Gene ID: (Human) 3687, (Mouse) 16411

          View more View less

          Function(s)
          receptor activity protein binding metal ion binding
          Process(es)
          cell adhesion integrin-mediated signaling pathway heterotypic cell-cell adhesion activated T cell proliferation defense response to virus positive regulation of protein targeting to mitochondrion organ morphogenesis extracellular matrix organization leukocyte migration
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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