Proteintech

CD11c/Integrin alpha X Polyclonal Antibody

CD11c/Integrin alpha X Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 6

CD11c/Integrin alpha X Antibody (17342-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 17342-1-AP ( CD11c/Integrin alpha X Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

CD11c/Integrin alpha X Antibody in Western Blot (WB)

CD11c/Integrin alpha X Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

17342-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 11 publications 11 publications

Immunohistochemistry (IHC)

View 20 publications 20 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 11 publications 11 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

View 4 publications 4 publications

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CD11c/Integrin alpha X Fusion Protein Ag11380 (21-352 aa encoded by BC038237)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: NLDTEELTA FRVDSAGFGD SVVQYANSWV VVGAPQKITA ANQTGGLYQC GYSTGACEPI GLQVPPEAVN MSLGLSLAST TSPSQLLACG PTVHHECGRN MYLTGLCFLL GPTQLTQRLP VSRQECPRQE QDIVFLIDGS GSISSRNFAT MMNFVRAVIS QFQRPSTQFS LMQFSNKFQT HFTFEEFRRS SNPLSLLASV HQLQGFTYTA TAIQNVVHRL FHASYGARRD AAKILIVITD GKKEGDSLDY KDVIPMADAA GIIRYAIGVG LAFQNRNSWK ELNDIASKPS QEHIFKVEDF DALKDIQNQL KEKIFAIEGT ETTSSSSFEL EMA (21-352 aa encoded by BC038237)

Target Information

CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Aspergillus cristatus attenuates DSS-induced intestinal barrier damage through reducing the oxidative stress, regulating short-chain fatty acid and inhibiting MAPK signaling pathways.

Journal of the science of food and agriculture

Wang X,Zeng X,Zhang X,Wei J,Zhang Y,Long F,Yue T,Yuan Y

Wed Mar 15 00:00:00 UTC 2023

Co-inhibition of immunoproteasome subunits LMP2 and LMP7 enables prevention of transplant arteriosclerosis.

Cardiovascular research

Li J,Hu S,Johnson HWB,Kirk CJ,Xian P,Song Y,Li Y,Liu N,Groettrup M,Basler M

Tue May 02 00:00:00 UTC 2023

Amnion-derived serum amyloid A1 participates in sterile inflammation of fetal membranes at parturition.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Lin YK,Zhang F,Lei WJ,Gan XW,Li MD,Pan F,Wang WS,Sun K

Sat Apr 01 00:00:00 UTC 2023

Comparison of proteomic landscape of extracellular vesicles in pleural effusions isolated by three strategies.

Frontiers in bioengineering and biotechnology

Yao X,Liao B,Chen F,Liu L,Wu K,Hao Y,Li Y,Wang Y,Fan R,Yin J,Liu L,Guo Y

Tue May 02 00:00:00 UTC 2023

CD40LG and GZMB were correlated with adipose tissue macrophage infiltration and involved in obstructive sleep apnea related metabolic dysregulation: Evidence from bioinformatics analysis.

Frontiers in genetics

Ming X,Cai W,Li Z,Yang X,Yang M,Pan D,Chen X

Thu Mar 16 00:00:00 UTC 2023

A new method for predicting the prognosis of colorectal cancer patients through a combination of multiple tumor-associated macrophage markers at the invasive front.

Heliyon

Wang X,Yuwen TJ,Zhong Y,Li ZG,Wang XY

Wed Feb 01 00:00:00 UTC 2023

The antitumour effects of caloric restriction are mediated by the gut microbiome.

Nature metabolism

Mao YQ,Huang JT,Zhang SL,Kong C,Li ZM,Jing H,Chen HL,Kong CY,Huang SH,Cai PR,Han B,Wang LS

Sun Jan 01 00:00:00 UTC 2023

Silver nanoparticles combat Salmonella Typhimurium: Suppressing intracellular infection and activating dendritic cells.

Colloids and surfaces. B, Biointerfaces

Gong J,Cheng X,Zuo J,Zhang Y,Lin J,Liu M,Jiang Y,Long Y,Si H,Gao X,Guo D,Gu N

Thu Jun 01 00:00:00 UTC 2023

The secretion of sIgA and dendritic cells activation in the intestinal of cyclophosphamide-induced immunosuppressed mice are regulated by Alhagi honey polysaccharides.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Cai G,Yang Y,Gu P,Li K,Adelijiang W,Zhu T,Liu Z,Wang D

Mon Aug 01 00:00:00 UTC 2022

Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation.

Drug delivery

Zheng J,Sun Y,Long T,Yuan D,Yue S,Zhang N,Yang Z

Thu Dec 01 00:00:00 UTC 2022

The Astragaloside IV Derivative LS-102 Ameliorates Obesity-Related Nephropathy.

Drug design, development and therapy

Li Z,Yang W,Yang Y,Wu J,Luo P,Liu Y

Mon Apr 04 00:00:00 UTC 2022

Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.

Biochemical pharmacology

Kang H,Dong Y,Peng R,Liu H,Guo Q,Song K,Zhu M,Yu K,Wu W,Li F

Tue Mar 01 00:00:00 UTC 2022

TSH-TSHR axis promotes tumor immune evasion.

Journal for immunotherapy of cancer

Wu Z,Xi Z,Xiao Y,Zhao X,Li J,Feng N,Hu L,Zheng R,Zhang N,Wang S,Huang T

Sat Jan 01 00:00:00 UTC 2022

Multiplex immunohistochemistry reveals cochlear macrophage heterogeneity and local auditory nerve inflammation in cisplatin-induced hearing loss.

Frontiers in neurology

Bedeir MM,Ninoyu Y,Nakamura T,Tsujikawa T,Hirano S

Tue Nov 08 00:00:00 UTC 2022

Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect.

Bioactive materials

Wang H,Liu H,Guo Y,Zai W,Li X,Xiong W,Zhao X,Yao Y,Hu Y,Zou Z,Wu J

Wed Jun 01 00:00:00 UTC 2022

Enhanced Immunotherapy Based on Combining the Pro-phagocytosis and Anti-phagocytosis Checkpoint Blockade for Tumor Eradication.

Journal of medicinal chemistry

Song W,Yang F,Yang H,Xu Y,Song SJ,Meng Y,Wei ST,Wan T,Zhou Y,Zhou B,Kuang J,Yu T,Qiu WX

Thu Nov 10 00:00:00 UTC 2022

Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflammasome Activation and the NF-κB Pathway.

Drug design, development and therapy

Liu J,Fan G,Tao N,Feng F,Meng C,Sun T

Tue Jun 21 00:00:00 UTC 2022

Pericyte mediates the infiltration, migration, and polarization of macrophages by CD163/MCAM axis in glioblastoma.

iScience

Zhang H,Zhang N,Wu W,Wang Z,Dai Z,Liang X,Zhang L,Peng Y,Luo P,Zhang J,Liu Z,Cheng Q,Liu Z

Fri Sep 16 00:00:00 UTC 2022

Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.

International journal of nanomedicine

Zhang J,Li Z,Liu L,Li L,Zhang L,Wang Y,Zhao J

Tue May 10 00:00:00 UTC 2022

Gaseous nitric oxide tumor ablation induces an anti-tumor abscopal effect.

Cancer cell international

Confino H,Dirbas FM,Goldshtein M,Yarkoni S,Kalaora R,Hatan M,Puyesky S,Levi Y,Malka L,Johnson M,Chaisson S,Monson JM,Avniel A,Lisi S,Greenberg D,Wolf I

Tue Dec 13 00:00:00 UTC 2022

Macrophage membrane-mediated targeted drug delivery for treatment of spinal cord injury regardless of the macrophage polarization states.

Asian journal of pharmaceutical sciences

Tang W,Yang Y,Yang L,Tang M,Chen Y,Li C

Thu Jul 01 00:00:00 UTC 2021

Ruyiping extract reduces lung metastasis in triple negative breast cancer by regulating macrophage polarization.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Yang R,Xie Y,Li Q,Ye Y,Shi Y,Zhao X,Wu C,Xu Y,Wang R,Zhang Y,Yang X,Han X,Liu S

Wed Sep 01 00:00:00 UTC 2021

Seed peptide lunasin ameliorates obesity-induced inflammation and regulates immune responses in C57BL/6J mice fed high-fat diet.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Hsieh CC,Wang YF,Lin PY,Peng SH,Chou MJ

Fri Jan 01 00:00:00 UTC 2021

Inflammation of the adipose tissue in the retroperitoneal cavity adjacent to pelvic endometriosis.

The journal of obstetrics and gynaecology research

Kubo K,Kamada Y,Hasegawa T,Sakamoto A,Nakatsuka M,Matsumoto T,Masuyama H

Fri Oct 01 00:00:00 UTC 2021

Preventive and Therapeutic Spermidine Treatment Attenuates Acute Colitis in Mice.

Journal of agricultural and food chemistry

Ma L,Ni L,Yang T,Mao P,Huang X,Luo Y,Jiang Z,Hu L,Zhao Y,Fu Z,Ni Y

Wed Feb 17 00:00:00 UTC 2021

Erucic Acid-Rich Yellow Mustard Oil Improves Insulin Resistance in KK-A^y Mice.

Molecules (Basel, Switzerland)

Takahashi A,Ishizaki M,Kimira Y,Egashira Y,Hirai S

Thu Jan 21 00:00:00 UTC 2021

Celastrol targets adenylyl cyclase-associated protein 1 to reduce macrophages-mediated inflammation and ameliorates high fat diet-induced metabolic syndrome in mice.

Acta pharmaceutica Sinica. B

Zhu Y,Wan N,Shan X,Deng G,Xu Q,Ye H,Sun Y

Sat May 01 00:00:00 UTC 2021

Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia.

Biomaterials

Wang H,Guo Y,Wang C,Jiang X,Liu H,Yuan A,Yan J,Hu Y,Wu J

Mon Feb 01 00:00:00 UTC 2021

Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removes LXR-induced lipogenesis.

Theranostics

Feng K,Ma C,Liu Y,Yang X,Yang Z,Chen Y,Xu T,Yang C,Zhang S,Li Q,Wei Z,Zhao D,Zeng P,Han J,Gao J,Chen Y,Duan Y

Tue Jul 27 00:00:00 UTC 2021

Cellular and physical microenvironments regulate the aggressiveness and sunitinib chemosensitivity of clear cell renal cell carcinoma.

The Journal of pathology

Nagase K,Akutagawa T,Rikitake-Yamamoto M,Morito S,Futamata M,Tobu S,Noguchi M,Toda S,Aoki S

Sat May 01 00:00:00 UTC 2021

The ACE2-deficient mouse: A model for a cytokine storm-driven inflammation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Wang J,Kaplan N,Wysocki J,Yang W,Lu K,Peng H,Batlle D,Lavker RM

Sat Aug 01 00:00:00 UTC 2020

Forensic pathological study on temporal appearance of dendritic cells in skin wounds.

International journal of legal medicine

Kuninaka Y,Ishida Y,Nosaka M,Shimada E,Kimura A,Ozaki M,Hata S,Michiue T,Yamamoto H,Furukawa F,Eisenmenger W,Kondo T

Sun Mar 01 00:00:00 UTC 2020

Attenuation of Diabetic Nephropathy in Diabetic Mice by Fasudil through Regulation of Macrophage Polarization.

Journal of diabetes research

Xie F,Lei J,Ran M,Li Y,Deng L,Feng J,Zhong Y,Li J

Thu May 27 00:00:00 UTC 2021

DC-SIGN-LEF1/TCF1-miR-185 feedback loop promotes colorectal cancer invasion and metastasis.

Cell death and differentiation

Yuan M,Zhang X,Zhang J,Wang K,Zhang Y,Shang W,Zhang Y,Cui J,Shi X,Na H,Fang D,Zuo Y,Ren S

Wed Jan 01 00:00:00 UTC 2020

Autophagy plays a positive role in induction of epidermal proliferation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Wang J,Kaplan N,Wang S,Yang W,Wang L,He C,Peng H

Sat Aug 01 00:00:00 UTC 2020

Deletion of atypical chemokine receptor 3 (ACKR3) increases immune cells at the fetal-maternal interface.

Placenta

Quinn KE,Matson BC,Caron KM

Mon Jun 01 00:00:00 UTC 2020

CD11c(+) dendritic cells coexpressing thymic stromal lymphopoietin receptor in animal model of eosinophilic otitis media.

Asia Pacific allergy

Hara R,Kudo N,Suzuki S,Miura T,Matsubara A

Thu Oct 01 00:00:00 UTC 2020

CD11c(+) dendritic cells coexpressing thymic stromal lymphopoietin receptor in animal model of eosinophilic otitis media.

Asia Pacific allergy

Hara R,Kudo N,Suzuki S,Miura T,Matsubara A

Thu Oct 01 00:00:00 UTC 2020

PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.

Journal of cellular and molecular medicine

Li Y,Zhou H,Li Y,Han L,Song M,Chen F,Shang G,Wang D,Wang Z,Zhang W,Zhong M

Sat Jun 01 00:00:00 UTC 2019

PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.

Journal of cellular and molecular medicine

Li Y,Zhou H,Li Y,Han L,Song M,Chen F,Shang G,Wang D,Wang Z,Zhang W,Zhong M

Sat Jun 01 00:00:00 UTC 2019

Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme.

Frontiers in immunology

Zhang Y,Feng J,Fu H,Liu C,Yu Z,Sun Y,She X,Li P,Zhao C,Liu Y,Liu T,Liu Q,Liu Q,Li G,Wu M

Wed Jun 17 00:00:00 UTC 2020

Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme.

Frontiers in immunology

Zhang Y,Feng J,Fu H,Liu C,Yu Z,Sun Y,She X,Li P,Zhao C,Liu Y,Liu T,Liu Q,Liu Q,Li G,Wu M

Wed Jun 17 00:00:00 UTC 2020

Protective Effects of Live Combined B. subtilis and E. faecium in Polymicrobial Sepsis Through Modulating Activation and Transformation of Macrophages and Mast Cells.

Frontiers in pharmacology

Guo L,Meng M,Wei Y,Lin F,Jiang Y,Cui X,Wang G,Wang C,Guo X

Thu Oct 01 00:00:00 UTC 2020

(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway.

International immunopharmacology

Zhang X,Xu F,Liu L,Feng L,Wu X,Shen Y,Sun Y,Wu X,Xu Q

Fri Dec 01 00:00:00 UTC 2017

(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway.

International immunopharmacology

Zhang X,Xu F,Liu L,Feng L,Wu X,Shen Y,Sun Y,Wu X,Xu Q

Fri Dec 01 00:00:00 UTC 2017

Obesity enhances carcinogen 7, 12-Dimethylbenz [a] anthracene -induced tumorigenesis in vitro and in vivo.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Hsieh CC,Peng SH,Chou MJ

Fri Dec 01 00:00:00 UTC 2017

Obesity enhances carcinogen 7, 12-Dimethylbenz [a] anthracene -induced tumorigenesis in vitro and in vivo.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Hsieh CC,Peng SH,Chou MJ

Fri Dec 01 00:00:00 UTC 2017

An injectable, low-toxicity phospholipid-based phase separation gel that induces strong and persistent immune responses in mice.

Biomaterials

Han L,Xue J,Wang L,Peng K,Zhang Z,Gong T,Sun X

Sat Oct 01 00:00:00 UTC 2016

An injectable, low-toxicity phospholipid-based phase separation gel that induces strong and persistent immune responses in mice.

Biomaterials

Han L,Xue J,Wang L,Peng K,Zhang Z,Gong T,Sun X

Sat Oct 01 00:00:00 UTC 2016

Epicardial adipocyte hypertrophy: Association with M1-polarization and toll-like receptor pathways in coronary artery disease patients.

Nutrition, metabolism, and cardiovascular diseases : NMCD

Vianello E,Dozio E,Arnaboldi F,Marazzi MG,Martinelli C,Lamont J,Tacchini L,Sigrüner A,Schmitz G,Corsi Romanelli MM

Tue Mar 01 00:00:00 UTC 2016

Epicardial adipocyte hypertrophy: Association with M1-polarization and toll-like receptor pathways in coronary artery disease patients.

Nutrition, metabolism, and cardiovascular diseases : NMCD

Vianello E,Dozio E,Arnaboldi F,Marazzi MG,Martinelli C,Lamont J,Tacchini L,Sigrüner A,Schmitz G,Corsi Romanelli MM

Tue Mar 01 00:00:00 UTC 2016

Indoleamine 2,3-dioxygenase expression in human inflammatory bowel disease.

European journal of gastroenterology & hepatology

Zhou L,Chen H,Wen Q,Zhang Y

Fri Jun 01 00:00:00 UTC 2012

Indoleamine 2,3-dioxygenase expression in human inflammatory bowel disease.

European journal of gastroenterology & hepatology

Zhou L,Chen H,Wen Q,Zhang Y

Fri Jun 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: CD11 antigen-like family member C; CD11c; complement component 3 receptor 4 subunit; integrin alpha X; Integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Leu M5; leu M5, alpha subunit; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain

View more View less

Gene Aliases: CD11C; ITGAX; SLEB6

View more View less

UniProt ID: (Human) P20702

View more View less

Entrez Gene ID: (Human) 3687

View more View less

Function(s)

receptor activity protein binding metal ion binding

Process(es)

cell adhesion integrin-mediated signaling pathway organ morphogenesis extracellular matrix organization heterotypic cell-cell adhesion leukocyte migration positive regulation of protein targeting to mitochondrion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

CD11c/Integrin alpha X Polyclonal Antibody

CD11c/Integrin alpha X Antibody (17342-1-AP) in IHC (P)

Product Details

17342-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Miscellaneous PubMed (MISC)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!