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CD11c/Integrin alpha X Monoclonal Antibody (2F1C10)

CD11c/Integrin alpha X Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CD11c/Integrin alpha X Antibody (60258-1-IG) in IHC (P)

Immunohistochemical analysis of paraffin-embedded Human tonsillitis tissue slide using (Product # 60258-1-Ig) CD11c/Integrin Alpha X antibody at dilution of 1:20,000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CD11c/Integrin alpha X Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

CD11c/Integrin alpha X Antibody in Western Blot (WB)

Product Image Gallery

Product Details

60258-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:800-1:3200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:20,000

Immunocytochemistry (ICC/IF)

View 10 publications 10 publications

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

2F1C10

Immunogen

CD11c/Integrin alpha X Fusion Protein Ag11350 (21-352 aa encoded by BC038237)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: NLDTEELTA FRVDSAGFGD SVVQYANSWV VVGAPQKITA ANQTGGLYQC GYSTGACEPI GLQVPPEAVN MSLGLSLAST TSPSQLLACG PTVHHECGRN MYLTGLCFLL GPTQLTQRLP VSRQECPRQE QDIVFLIDGS GSISSRNFAT MMNFVRAVIS QFQRPSTQFS LMQFSNKFQT HFTFEEFRRS SNPLSLLASV HQLQGFTYTA TAIQNVVHRL FHASYGARRD AAKILIVITD GKKEGDSLDY KDVIPMADAA GIIRYAIGVG LAFQNRNSWK ELNDIASKPS QEHIFKVEDF DALKDIQNQL KEKIFAIEGT ETTSSSSFEL EMA (21-352 aa encoded by BC038237)

Target Information

CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Opposing Roles of Sphingosine 1-Phosphate Receptors 1 and 2 in Fat Deposition and Glucose Tolerance in Obese Male Mice.

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Tissue-resident FOLR2⁺ macrophages associate with CD8⁺ T cell infiltration in human breast cancer.

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The Journal of experimental medicine

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Tumor β-catenin expression is associated with immune evasion in non-small cell lung cancer with high tumor mutation burden.

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Mon Mar 01 00:00:00 UTC 2021

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Experimental cell research

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Experimental cell research

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Bioinformatics

Protein Aliases: CD11 antigen-like family member C; CD11c; complement component 3 receptor 4 subunit; integrin alpha X; Integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); Leu M5; leu M5, alpha subunit; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain

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Gene Aliases: CD11C; ITGAX; SLEB6

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UniProt ID: (Human) P20702

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Entrez Gene ID: (Human) 3687

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Function(s)

receptor activity protein binding metal ion binding

Process(es)

cell adhesion integrin-mediated signaling pathway organ morphogenesis extracellular matrix organization heterotypic cell-cell adhesion leukocyte migration positive regulation of protein targeting to mitochondrion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CD11c/Integrin alpha X Monoclonal Antibody (2F1C10)

CD11c/Integrin alpha X Antibody (60258-1-IG) in IHC (P)

Product Details

60258-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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