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Invitrogen
CD123 Polyclonal Antibody
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FIGURE: 1 / 2
CD123 Antibody (PA5-86838) in WB
Western blot analysis of CD123 in Lane 1: A549 whole cell lysate (40 µg), Lane 2: HeLa whole cell lysate (40 µg), Lane 3: PC12 whole cell lysate (40 µg), Lane 4: MEF whole cell lysate (40 µg). Samples were incubated with CD123 polyclonal antibody (Product # PA5-86838) at a dilution of 1:500.
Product Details
PA5-86838
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to residues in Human IL3RA
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2803597
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD123; CD123 antigen; cytokine receptor-like protein CYRL; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; Interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha
Gene Aliases: CD123; CDw123; Cyrl; hIL-3Ra; IL3R; IL3RA; IL3RAY; IL3RX; IL3RY; SUT-1
UniProt ID: (Human) P26951, (Mouse) P26952
Entrez Gene ID: (Human) 3563, (Rat) 246144, (Mouse) 16188
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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