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Invitrogen
CD13 Recombinant Rabbit Monoclonal Antibody (SC70-01)
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Product Details
MA5-32226
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SC70-01
Immunogen
Synthetic peptide within Human CD13 aa 409-442
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809512
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alanyl (membrane) aminopeptidase; Alanyl aminopeptidase; Aminopeptidase M; Aminopeptidase N; aminopeptidase N/CD13; AP-M; AP-N; CD13; cluster of differentiation antigen 13 (CD13); gp150; h AP-N; hAPN; kidney aminopeptidase M; Kidney Zn peptidase; KZP; leucine arylaminopeptidase 1; membrane alanine aminopeptidase; membrane alanyl aminopeptidase; Membrane protein p161; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13
Gene Aliases: ANPEP; AP-M; AP-N; Apm; APN; CD13; GP150; KZP; Lap-1; LAP1; P150; PEPN; rAPN
UniProt ID: (Human) P15144, (Mouse) P97449, (Rat) P15684
Entrez Gene ID: (Human) 290, (Mouse) 16790, (Rat) 81641
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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