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MA1-70088 detects CD147 in mouse samples.
MA1-70088 has been successfully used in flow cytometry, Western blot and immunohistochemistry procedures.
The MA1-70088 immunogen is recombinant md0-2rCD4d3+4.
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5A11/Basigin; Basic immunoglobulin superfamily; Basigin; CD147; gp 42; HT7 antigen; Membrane glycoprotein gp42; neurothelin
Gene Aliases: AI115436; AI325119; Bsg; CD147; EMMPRIN; HT-7
UniProt ID: (Mouse) P18572
Entrez Gene ID: (Mouse) 12215
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