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CD155 Antibody (17-1551-82) in Flow
Staining of C57BL/6 thymocytes with Anti-Mouse CD4, Anti-Mouse CD8a and 0.5 µg of Rat IgG2a kappa Isotype Control APC (Product # 17-4321-81) (blue histogram) or 0.5 µg of Anti-Mouse CD155 APC (purple histogram). Double-positive (CD4+CD8+) cells were used for analysis.
Product Details
17-1551-82
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Recommended Isotype Control
Class
Monoclonal
Type
Antibody
Clone
TX56
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Concentration
0.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1603205
Product Specific Information
Description: This TX56 monoclonal antibody reacts with mouse CD155 (also known as poliovirus receptor or PVR), a member of the Ig superfamily of nectins and nectin-like proteins. CD155 is expressed on thymocytes (e.g. CD4+CD8+ and CD4+ cells), peripheral T and B lymphocytes (e.g. regulatory T cells, activated T cells, marginal zone B cells, and plasma cells), natural killer (NK) cells, dendritic cells (e.g. mature and activated), and monocytes. CD155 interacts with other nectins, including Nectin-3 and the extraceullar matrix protein vitronectin, the adhesion molecule CD226/DNAM-1, and the NK cell receptor CD96. CD155 plays a role in cell-cell adhesion, including formation of adherens junctions, cell migration, polarization, and NK-mediated cytotoxicity. In humans, but not in mice, CD155 is the receptor for poliovirus.
Applications Reported: This TX56 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This TX56 antibody has been tested by flow cytometric analysis on mouse thymocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ25946; nectin-like 5; poliovirus receptor; sCD112; soluble CD112; tumor-associated antigen 1
Gene Aliases: 3830421F03Rik; CD155; D7Ertd458e; HVED; mE4; necl-5; PVS; Taa1; Tage4
Entrez Gene ID: (Mouse) 52118
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