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Positive Control: PC-3M cell lysate, SHSY5Y cell lysate, A549 cell lysate, rat bladder tissue, human breast cancer tissue, mouse liver tissue, mouse stomach tissue, SHSY5Y.
Subcellular Location: Cell membrane, Cell projection, Membrane, Secreted.
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activated leukocyte cell adhesion molecule; BEN; CD166; CD166 antigen; FLJ38514; HB2; KG-CAM; MGC71733; Protein DM-GRASP; Protein MEMD; SB-10 antigen
Gene Aliases: AI853494; ALCAM; BEN; CD166; DM-GRASP; MEMD; MuSC; SC1
UniProt ID: (Human) Q13740, (Rat) O35112, (Mouse) Q61490
Entrez Gene ID: (Human) 214, (Rat) 79559, (Mouse) 11658
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