Product References
L1CAM immunocapture generates a unique extracellular vesicle population with a reproducible miRNA fingerprint.
RNA biology
Dunlop RA,Banack SA,Cox PA
13-1719-82 was used in Immunocapture to conclude that L1CAM immunocapture generates a unique fraction of EVs that consistently and robustly replicates a miRNA fingerprint which differentiates ALS patients from controls.
Sun Jan 01 00:00:00 UTC 2023
Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial.
Scientific reports
Burrows K,Figueroa-Hall LK,Kuplicki R,Stewart JL,Alarbi AM,Ramesh R,Savitz JB,Teague TK,Risbrough VB,Paulus MP
13-1719-82 was used in Western Blot, Flow Cytometry to demonstrate that miR-27b could be an important messaging molecule that is associated with regulating the processing of positive or negative valenced information.
Mon Jan 17 00:00:00 UTC 2022
Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial.
Scientific reports
Burrows K,Figueroa-Hall LK,Kuplicki R,Stewart JL,Alarbi AM,Ramesh R,Savitz JB,Teague TK,Risbrough VB,Paulus MP
13-1719-82 was used in Western Blot, Flow Cytometry to demonstrate that miR-27b could be an important messaging molecule that is associated with regulating the processing of positive or negative valenced information.
Mon Jan 17 00:00:00 UTC 2022
Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain.
Journal of extracellular vesicles
You Y,Muraoka S,Jedrychowski MP,Hu J,McQuade AK,Young-Pearse T,Aslebagh R,Shaffer SA,Gygi SP,Blurton-Jones M,Poon WW,Ikezu T
Published figure using CD171 monoclonal antibody (Product # 13-1719-82) in Western Blot
Sat Jan 01 00:00:00 UTC 2022
Evaluation of blood-based, extracellular vesicles as biomarkers for aging-related TDP-43 pathology.
Alzheimer's & dementia (Amsterdam, Netherlands)
Winston CN,Sukreet S,Lynch H,Lee VM,Wilcock DM,Nelson PT,Rissman RA
13-1719-82 was used in Flow cytometry/Cell sorting to evaluate TDP-43 in plasma ADEVs derived from autopsy confirmed LATE-NC subjects, with or without comorbid Alzheimer's disease pathology.
Mon Sep 09 00:00:00 UTC 2024
Evaluation of blood-based, extracellular vesicles as biomarkers for aging-related TDP-43 pathology.
Alzheimer's & dementia (Amsterdam, Netherlands)
Winston CN,Sukreet S,Lynch H,Lee VM,Wilcock DM,Nelson PT,Rissman RA
13-1719-82 was used in Flow cytometry/Cell sorting to evaluate TDP-43 in plasma ADEVs derived from autopsy confirmed LATE-NC subjects, with or without comorbid Alzheimer's disease pathology.
Mon Sep 09 00:00:00 UTC 2024
Abnormal levels of mitochondrial Ca2+ channel proteins in plasma neuron-derived extracellular vesicles of early schizophrenia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Goetzl EJ,Srihari VH,Mustapic M,Kapogiannis D,Heninger GR
13-1719-82 was used in Affinity Purification to assess levels of functionally prominent mitochondrial calcium ion channel proteins in plasma neuron-derived extracellular vesicles (NDEVs) of living patients with first episodes of psychosis (FP) and matched controls (Cs).
Mon Aug 01 00:00:00 UTC 2022
Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance.
Molecular psychiatry
Nasca C,Dobbin J,Bigio B,Watson K,de Angelis P,Kautz M,Cochran A,Mathé AA,Kocsis JH,Lee FS,Murrough JW,McEwen BS,Rasgon N
Published figure using CD171 monoclonal antibody (Product # 13-1719-82) in Western Blot
Wed Sep 01 00:00:00 UTC 2021
Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance.
Molecular psychiatry
Nasca C,Dobbin J,Bigio B,Watson K,de Angelis P,Kautz M,Cochran A,Mathé AA,Kocsis JH,Lee FS,Murrough JW,McEwen BS,Rasgon N
Published figure using CD171 monoclonal antibody (Product # 13-1719-82) in Western Blot
Wed Sep 01 00:00:00 UTC 2021
Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease.
Cells
Delgado-Peraza F,Nogueras-Ortiz CJ,Volpert O,Liu D,Goetzl EJ,Mattson MP,Greig NH,Eitan E,Kapogiannis D
Published figure using CD171 monoclonal antibody (Product # 13-1719-82) in Western Blot
Fri Apr 23 00:00:00 UTC 2021
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations.
Cells
Sun B,Tang N,Peluso MJ,Iyer NS,Torres L,Donatelli JL,Munter SE,Nixon CC,Rutishauser RL,Rodriguez-Barraquer I,Greenhouse B,Kelly JD,Martin JN,Deeks SG,Henrich TJ,Pulliam L
13-1719 was used in Immunopurification to investigate the mechanisms to explain long-term neurological sequelae following COVID-19 recovery.
Sat Feb 13 00:00:00 UTC 2021
Plasma Levels of Neuron- and Astrocyte-Derived Exosomal Amyloid Beta1-42, Amyloid Beta1-40, and Phosphorylated Tau Levels in Schizophrenia Patients and Non-psychiatric Comparison Subjects: Relationships With Cognitive Functioning and Psychopathology.
Frontiers in psychiatry
Lee EE,Winston-Gray C,Barlow JW,Rissman RA,Jeste DV
13-1719 was used in Flow cytometry/Cell sorting to study exosomal amyloid and tau protein levels in people with schizophrenia.
Sat Mar 27 00:00:00 UTC 2021
Plasma Levels of Neuron- and Astrocyte-Derived Exosomal Amyloid Beta1-42, Amyloid Beta1-40, and Phosphorylated Tau Levels in Schizophrenia Patients and Non-psychiatric Comparison Subjects: Relationships With Cognitive Functioning and Psychopathology.
Frontiers in psychiatry
Lee EE,Winston-Gray C,Barlow JW,Rissman RA,Jeste DV
13-1719 was used in Flow cytometry/Cell sorting to study exosomal amyloid and tau protein levels in people with schizophrenia.
Sat Mar 27 00:00:00 UTC 2021
An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron disease.
Open biology
Banack SA,Dunlop RA,Cox PA
13-1719 was used in Western Blotting to report eight miRNA sequences which significantly distinguish ALS/MND patients from controls in a replicated experiment using a second cohort of patients and controls.
Mon Jun 01 00:00:00 UTC 2020
Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity.
Frontiers in neuroscience
Winston CN,Romero HK,Ellisman M,Nauss S,Julovich DA,Conger T,Hall JR,Campana W,O'Bryant SE,Nievergelt CM,Baker DG,Risbrough VB,Rissman RA
13-1719-82 was used in Flow Cytometry to examine the potential of neuronally-derived (NDE) and astrocytic-derived (ADE) exosome cargo proteins as biomarkers of chronic mTBI in younger adults by examing plasma exosomes from a prospective longitudinal study of combat-related risk and resilience, marine resiliency study II (MRSII).
Sun Jul 21 00:00:00 UTC 2024
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization.
Nature cell biology
Er EE,Valiente M,Ganesh K,Zou Y,Agrawal S,Hu J,Griscom B,Rosenblum M,Boire A,Brogi E,Giancotti FG,Schachner M,Malladi S,Massagué J
Published figure using CD171 monoclonal antibody (Product # 13-1719-82) in Immunohistochemistry (PFA fixed)
Wed Aug 01 00:00:00 UTC 2018
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization.
Nature cell biology
Er EE,Valiente M,Ganesh K,Zou Y,Agrawal S,Hu J,Griscom B,Rosenblum M,Boire A,Brogi E,Giancotti FG,Schachner M,Malladi S,Massagué J
Published figure using CD171 monoclonal antibody (Product # 13-1719-82) in Immunohistochemistry (PFA fixed)
Wed Aug 01 00:00:00 UTC 2018
Increased DJ-1 and α-Synuclein in Plasma Neural-Derived Exosomes as Potential Markers for Parkinson's Disease.
Frontiers in aging neuroscience
Zhao ZH,Chen ZT,Zhou RL,Zhang X,Ye QY,Wang YZ
13-1719 was used in Immunoprecipitation to show that DJ-1 in plasma neural-derived exosomes may be used as a potential biomarker as α-synuclein in PD and they might participate in the mechanism of PD together.
Thu Oct 01 00:00:00 UTC 2020
Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles.
International journal of molecular sciences
Guix FX,Corbett GT,Cha DJ,Mustapic M,Liu W,Mengel D,Chen Z,Aikawa E,Young-Pearse T,Kapogiannis D,Selkoe DJ,Walsh DM
13-1719-82 was used in Affinity Purification to demonstrate the presence of minute amounts of free-floating and exosome-contained full-length tau in human biofluids.
Tue Feb 27 00:00:00 UTC 2018
Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease.
Human brain mapping
Mullins RJ,Mustapic M,Goetzl EJ,Kapogiannis D
13-1719 was used in Immunoprecipitation to characterise exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease.
Sat Apr 01 00:00:00 UTC 2017
Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes.
Frontiers in neuroscience
Mustapic M,Eitan E,Werner JK,Berkowitz ST,Lazaropoulos MP,Tran J,Goetzl EJ,Kapogiannis D
13-1719 was used in Immunoprecipitation to utilise harvested extracellular vesicles enriched for neuronal origin, from peripheral blood as a biomarker discovery platform for neurological disorders.
Wed Jul 17 00:00:00 UTC 2024
Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging.
Annals of clinical and translational neurology
Abner EL,Jicha GA,Shaw LM,Trojanowski JQ,Goetzl EJ
13-1719 was used in an ELISA assay to define changes in levels of plasma neuronal exosomal proteins associated with normal ageing in cognitively intact subjects.
Sun May 01 00:00:00 UTC 2016
Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile.
Alzheimer's & dementia (Amsterdam, Netherlands)
Winston CN,Goetzl EJ,Akers JC,Carter BS,Rockenstein EM,Galasko D,Masliah E,Rissman RA
13-1719 was used in in vitro experiments to conclude that plasma NDEs from demented patients seeded tau aggregation and induced AD-like neuropathology in normal mouse CNS.
Wed Jul 13 00:00:00 UTC 2016
Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease.
Neurology
Goetzl EJ,Boxer A,Schwartz JB,Abner EL,Petersen RC,Miller BL,Kapogiannis D
13-1719 was used in an ELISA assay to confirm early neuronal lysosomal dysfunction in Alzheimer disease patients, and suggest that these proteins may be useful biomarkers in large prospective studies.
Tue Jul 07 00:00:00 UTC 2015
Low neural exosomal levels of cellular survival factors in Alzheimer's disease.
Annals of clinical and translational neurology
Goetzl EJ,Boxer A,Schwartz JB,Abner EL,Petersen RC,Miller BL,Carlson OD,Mustapic M,Kapogiannis D
13-1719 was used in an ELISA assay to quantify transcription factors that mediate neuronal defenses against stress in plasma neural-derived exosomes of Alzheimer's disease or frontotemporal dementia patients and matched controls.
Wed Jul 01 00:00:00 UTC 2015
Serpins promote cancer cell survival and vascular co-option in brain metastasis.
Cell
Valiente M,Obenauf AC,Jin X,Chen Q,Zhang XH,Lee DJ,Chaft JE,Kris MG,Huse JT,Brogi E,Massagué J
Published figure using CD171 monoclonal antibody (Product # 13-1719-82) in Western Blot
Thu Feb 27 00:00:00 UTC 2014
