Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Mar 01 00:00:00 UTC 2024
Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects.
Bioactive materials
Li S,Zhang L,Liu C,Kim J,Su K,Chen T,Zhao L,Lu X,Zhang H,Cui Y,Cui X,Yuan F,Pan H
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon May 01 00:00:00 UTC 2023
Traumatic brain injury stimulates sympathetic tone-mediated bone marrow myelopoiesis to favor fracture healing.
Signal transduction and targeted therapy
Liu W,Chen W,Xie M,Chen C,Shao Z,Zhang Y,Zhao H,Song Q,Hu H,Xing X,Cai X,Deng X,Li X,Wang P,Liu G,Xiong L,Lv X,Zhang Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Wed Jul 05 00:00:00 UTC 2023
Hydrochlorothiazide-induced glucose metabolism disorder is mediated by the gut microbiota via LPS-TLR4-related macrophage polarization.
iScience
Luo JQ,Ren H,Chen MY,Zhao Q,Yang N,Liu Q,Gao YC,Zhou HH,Huang WH,Zhang W
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Jul 21 00:00:00 UTC 2023
TREM2 expression promotes liver and peritoneal M2 macrophage polarization in mice infected with Schistosoma japonicum.
Journal of cellular and molecular medicine
Zhu D,Huang M,Shen P,Zhang B,Chen G,Chen J,Duan L,Duan Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Tue Aug 01 00:00:00 UTC 2023
A pref-1-controlled non-inflammatory mechanism of insulin resistance.
iScience
Huang Y,Cui D,Chen L,Tong H,Wu H,Muller GK,Qi Y,Wang S,Xu J,Gao X,Fifield KE,Wang L,Xia Z,Vanderluit JL,Liu S,Leng L,Sun G,McGuire J,Young LH,Bucala R,Qi D
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Jun 16 00:00:00 UTC 2023
High-Dose Acetaminophen with N-acetylcysteine Rescue Inhibits M2 Polarization of Tumor-Associated Macrophages.
Cancers
Bryan A,Pingali P,Joslyn M,Li H,Bernas T,Koblinski J,Landry J,Lee WS,Patel B,Neuwelt A
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Sep 28 00:00:00 UTC 2023
Dipeptidyl peptidase 4 inhibitor reduces tumor-associated macrophages and enhances anti-PD-L1-mediated tumor suppression in non-small cell lung cancer.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Zuo B,Li T,Liu X,Wang S,Cheng J,Liu X,Cui W,Shi H,Ling C
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Wed Nov 01 00:00:00 UTC 2023
MIR222HG attenuates macrophage M2 polarization and allergic inflammation in allergic rhinitis by targeting the miR146a-5p/TRAF6/NF-κB axis.
Frontiers in immunology
Wen S,Li F,Tang Y,Dong L,He Y,Deng Y,Tao Z
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri May 26 00:00:00 UTC 2023
Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.
Materials today. Bio
Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2023
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization.
NPJ Regenerative medicine
Wang J,Xue Y,Wang Y,Liu C,Hu S,Zhao H,Gu Q,Yang H,Huang L,Zhou X,Shi Q
12-2061-82 was used in Flow Cytometry to suggest that BMP2pp may be a potential option for treating prosthetic loosening induced by wear debris from prostheses.
Thu Feb 09 00:00:00 UTC 2023
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization.
NPJ Regenerative medicine
Wang J,Xue Y,Wang Y,Liu C,Hu S,Zhao H,Gu Q,Yang H,Huang L,Zhou X,Shi Q
12-2061-82 was used in Flow Cytometry to suggest that BMP2pp may be a potential option for treating prosthetic loosening induced by wear debris from prostheses.
Thu Feb 09 00:00:00 UTC 2023
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Veterinary research
Feng L,Luo G,Li Y,Zhang C,Liu Y,Liu Y,Chen H,He D,Zhu Y,Gan L
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Tue Mar 14 00:00:00 UTC 2023
L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis.
Journal of applied microbiology
Zhu Q,Zai H,Zhang K,Zhang X,Luo N,Li X,Hu Y,Wu Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2022
G9a promotes inflammation in Streptococcus pneumoniae induced pneumonia mice by stimulating M1 macrophage polarization and H3K9me2 methylation in FOXP1 promoter region.
Annals of translational medicine
Li Y,Li G,Zhang L,Li Y,Zhao Z
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sun May 01 00:00:00 UTC 2022
Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury.
International journal of biological sciences
Qian Z,Chen H,Xia M,Chang J,Li X,Ye S,Wu S,Jiang S,Bao J,Wang B,Kong R,Zhang S,Zheng S,Cao X,Hong X
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Apr 15 00:00:00 UTC 2022
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
Journal of nanobiotechnology
Li K,Yan G,Huang H,Zheng M,Ma K,Cui X,Lu D,Zheng L,Zhu B,Cheng J,Zhao J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Jan 20 00:00:00 UTC 2022
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy.
JCI insight
Howard ZM,Gomatam CK,Rabolli CP,Lowe J,Piepho AB,Bansal SS,Accornero F,Rafael-Fortney JA
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Oct 10 00:00:00 UTC 2022
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Cancer immunology research
Wu Q,Huang Q,Jiang Y,Sun F,Liang B,Wang J,Hu X,Sun M,Ma Z,Shi Y,Liang Y,Tan Y,Zeng D,Yao F,Xu X,Yao Z,Li S,Rong X,Huang N,Sun L,Liao W,Shi M
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Tue Feb 01 00:00:00 UTC 2022
TIM3 Expression in Anaplastic-Thyroid-Cancer-Infiltrating Macrophages: An Emerging Immunotherapeutic Target.
Biology
Palacios LM,Peyret V,Viano ME,Geysels RC,Chocobar YA,Volpini X,Pellizas CG,Nicola JP,Motran CC,Rodriguez-Galan MC,Fozzatti L
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Nov 03 00:00:00 UTC 2022
EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis.
Cell death & disease
Zhang X,Chen C,Ling C,Luo S,Xiong Z,Liu X,Liao C,Xie P,Liu Y,Zhang L,Chen Z,Liu Z,Tang J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Nov 07 00:00:00 UTC 2022
Anti-CD52 antibody treatment in murine experimental autoimmune encephalomyelitis induces dynamic and differential modulation of innate immune cells in peripheral immune and central nervous systems.
Immunology
Barbour M,Wood R,Harte T,Bushell TJ,Jiang HR
12-2061-82 was used in Flow Cytometry to support the CNS-specific beneficial effect of alemtuzumab treatment on inhibiting neuroinflammation in multiple sclerosis patients.
Tue Mar 01 00:00:00 UTC 2022
Local and systemic inflammation triggers different outcomes of tumor growth related to infiltration of anti-tumor or pro-tumor macrophages.
Chinese medical journal
Liu X,Jiang Q,Shen S,Hou Y
12-2061-82 was used in Flow cytometry/Cell sorting to suggest that the different outcomes of tumor growth might be attributed to the infiltration of anti-tumor or pro-tumor immune cells, especially M1 or M2 type macrophages into tumor microenvironment.
Fri Aug 05 00:00:00 UTC 2022
The cephalic phase of insulin release is modulated by IL-1β.
Cell metabolism
Wiedemann SJ,Trimigliozzi K,Dror E,Meier DT,Molina-Tijeras JA,Rachid L,Le Foll C,Magnan C,Schulze F,Stawiski M,Häuselmann SP,Méreau H,Böni-Schnetzler M,Donath MY
12-2061-82 was used in Flow cytometry/Cell sorting to describe that this incretin-like effect of IL-1β involves neuronal transmission.
Tue Jul 05 00:00:00 UTC 2022
Glutamine is essential for overcoming the immunosuppressive microenvironment in malignant salivary gland tumors.
Theranostics
Cao S,Hung YW,Wang YC,Chung Y,Qi Y,Ouyang C,Zhong X,Hu W,Coblentz A,Maghami E,Sun Z,Lin HH,Ann DK
12-2061-82 was used in Flow cytometry/Cell sorting to determine if attenuated host autophagy is sufficient to induce tumor rejection through reinforced adaptive immunity and whether dietary glutamine supplementation, mimicking attenuated host autophagy, is capable of promoting antitumor immunity.
Tue Aug 16 00:00:00 UTC 2022
A Novel Selective Axl/Mer/CSF1R Kinase Inhibitor as a Cancer Immunotherapeutic Agent Targeting Both Immune and Tumor Cells in the Tumor Microenvironment.
Cancers
Jeon Y,Kang H,Yang Y,Park D,Choi B,Kim J,Kim J,Nam K
12-2061-82 was used in Flow Cytometry to present Q702, a selective, potent small molecule inhibitor targeting Axl, Mer, and CSF1R, for oral administration.
Sun Oct 02 00:00:00 UTC 2022
Pirfenidone modulates macrophage polarization and ameliorates radiation-induced lung fibrosis by inhibiting the TGF-β1/Smad3 pathway.
Journal of cellular and molecular medicine
Ying H,Fang M,Hang QQ,Chen Y,Qian X,Chen M
12-2061-82 was used in Flow cytometry/Cell sorting to investigate the use of pirfenidone in treating radiation-induced lung injury in mouse models.
Wed Sep 01 00:00:00 UTC 2021
Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.
Cells
Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Nov 15 00:00:00 UTC 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Jan 24 00:00:00 UTC 2022
Resolving macrophage polarization through distinct Ca2+ entry channel that maintains intracellular signaling and mitochondrial bioenergetics.
iScience
Nascimento Da Conceicao V,Sun Y,Ramachandran K,Chauhan A,Raveendran A,Venkatesan M,DeKumar B,Maity S,Vishnu N,Kotsakis GA,Worley PF,Gill DL,Mishra BB,Madesh M,Singh BB
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Nov 19 00:00:00 UTC 2021
Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage polarization.
Stem cell research & therapy
Dong B,Wang C,Zhang J,Zhang J,Gu Y,Guo X,Zuo X,Pan H,Hsu AC,Wang G,Wang F
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Wed Mar 24 00:00:00 UTC 2021
PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway.
Frontiers in immunology
Kong F,Sun K,Zhu J,Li F,Lin F,Sun X,Luo X,Ren C,Lu L,Zhao S,Sun J,Wang Y,Shi J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Nov 01 00:00:00 UTC 2021
Azithromycin alleviates systemic lupus erythematosus via the promotion of M2 polarisation in lupus mice.
Cell death discovery
Wang J,Chen Q,Zhang Z,Wang S,Wang Y,Xiang M,Liang J,Xu J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Fri Apr 16 00:00:00 UTC 2021
Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice.
Frontiers in pharmacology
Han H,Peng G,Meister M,Yao H,Yang JJ,Zou MH,Liu ZR,Ji X
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sat Apr 02 00:00:00 UTC 2022
Thymopentin treatment of murine premature ovarian failure via attenuation of immune cell activity and promotion of the BMP4/Smad9 signalling pathway.
International journal of medical sciences
Zhu X,Liu J,Pan H,Geng Z,Huang W,Liu T,Zhang B
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Immunocytochemistry
Tue Mar 15 00:00:00 UTC 2022
Thymopentin treatment of murine premature ovarian failure via attenuation of immune cell activity and promotion of the BMP4/Smad9 signalling pathway.
International journal of medical sciences
Zhu X,Liu J,Pan H,Geng Z,Huang W,Liu T,Zhang B
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Immunocytochemistry
Tue Mar 15 00:00:00 UTC 2022
Macrophage-derived EDA-A2 inhibits intestinal stem cells by targeting miR-494/EDA2R/β-catenin signaling in mice.
Communications biology
Song L,Chang R,Sun X,Lu L,Gao H,Lu H,Lin R,Xu X,Liu Z,Zhan L
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Tue Feb 16 00:00:00 UTC 2021
Hyperoside Suppresses Renal Inflammation by Regulating Macrophage Polarization in Mice With Type 2 Diabetes Mellitus.
Frontiers in immunology
Liu J,Zhang Y,Sheng H,Liang C,Liu H,Moran Guerrero JA,Lu Z,Mao W,Dai Z,Liu X,Zhang L
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Feb 10 00:00:00 UTC 2022
Adrenomedullin 2 improves bone regeneration in type 1 diabetic rats by restoring imbalanced macrophage polarization and impaired osteogenesis.
Stem cell research & therapy
Wang F,Kong L,Wang W,Shi L,Wang M,Chai Y,Xu J,Kang Q
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu May 13 00:00:00 UTC 2021
Ferumoxytol-β-glucan Inhibits Melanoma Growth via Interacting with Dectin-1 to Polarize Macrophages into M1 Phenotype.
International journal of medical sciences
Liu X,Xu Y,Li Y,Pan Y,Zhao S,Hou Y
12-2061-82 was used in Flow cytometry/Cell sorting to create a nanocomposite of Ferumoxytol (FMT) surface-coated with β-glucan (FMT-β-glucan), which effectively suppressed melanoma growth by promoting the polarization of M1 macrophages in the tumor microenvironment, enhancing the antitumor effect both in vivo and in vitro, likely through the upregulation of Dectin-1 and activation of MAPK and NF-κB signaling pathways in macrophages.
Mon Jan 10 00:00:00 UTC 2022
Oxygen-Enriched Metal-Phenolic X-Ray Nanoprocessor for Cancer Radio-Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sang W,Xie L,Wang G,Li J,Zhang Z,Li B,Guo S,Deng CX,Dai Y
12-2061 was used in Flow cytometry/Cell sorting to presents a multifunctional metal-phenolic nanoplatform for efficient X-ray mediated RT-RDT in combination with immunotherapy and may provide a new therapeutic option for cancer treatment.
Mon Feb 01 00:00:00 UTC 2021
Requirement of direct contact between chondrocytes and macrophages for the maturation of regenerative cartilage.
Scientific reports
Kanda K,Asawa Y,Inaki R,Fujihara Y,Hoshi K,Hikita A
12-2061-82 was used in Flow Cytometry to provide insights for establishing a method of in vitro cartilage regeneration.
Thu Nov 18 00:00:00 UTC 2021
BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functions.
Cell death & disease
Zhang D,Huang J,Wang F,Ding H,Cui Y,Yang Y,Xu J,Luo H,Gao Y,Pan L,Wu Y,Gong Y,Xie L,Liu Z,Qu Y,Zhang L,Liu W,Zhang W,Zhao S,Yi Q,Niu T,Zheng Y
12-2061-82 was used in Flow Cytometry to demonstrate the role of the polycomb-group protein, BMI1, in the modulation of pro-myeloma macrophages.
Sat May 15 00:00:00 UTC 2021
Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus.
Journal of neuroinflammation
Chen KE,Lainez NM,Nair MG,Coss D
12-2061-82 was used in Flow Cytometry to demonstrate a new connection between the adipose tissue and the hypothalamus in obesity that contributes to neuroinflammation and hypothalamic pathologies.
Mon Jun 21 00:00:00 UTC 2021
The FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ.
Experimental & molecular medicine
Lee YS,Song SJ,Hong HK,Oh BY,Lee WY,Cho YB
12-2061 was used in Flow cytometry/Cell sorting to suggest that macrophage PI3Kγ may be a promising target for immunotherapy in colon cancer.
Fri May 01 00:00:00 UTC 2020
The FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ.
Experimental & molecular medicine
Lee YS,Song SJ,Hong HK,Oh BY,Lee WY,Cho YB
12-2061 was used in Flow cytometry/Cell sorting to suggest that macrophage PI3Kγ may be a promising target for immunotherapy in colon cancer.
Fri May 01 00:00:00 UTC 2020
Macrophage polarization plays roles in bone formation instructed by calcium phosphate ceramics.
Journal of materials chemistry. B
Li M,Guo X,Qi W,Wu Z,de Bruijn JD,Xiao Y,Bao C,Yuan H
12-2061 was used in Flow cytometry/Cell sorting to investigate the roles of macrophages in material-instructed bone formation.
Wed Mar 04 00:00:00 UTC 2020
Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-β1 up-regulate miR-132 and promote mouse M2 macrophage polarization.
Journal of cellular and molecular medicine
Wang Y,Han B,Wang Y,Wang C,Zhang H,Xue J,Wang X,Niu T,Niu Z,Chen Y
12-2061 was used in Flow cytometry/Cell sorting to provide evidence reporting that MSC-secreted EVs carry TGF-β1 to promote M2 polarization of macrophages via modulation of the miR-132/Mycbp2/TSC2 axis.
Sun Nov 01 00:00:00 UTC 2020
Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-β1 up-regulate miR-132 and promote mouse M2 macrophage polarization.
Journal of cellular and molecular medicine
Wang Y,Han B,Wang Y,Wang C,Zhang H,Xue J,Wang X,Niu T,Niu Z,Chen Y
12-2061 was used in Flow cytometry/Cell sorting to provide evidence reporting that MSC-secreted EVs carry TGF-β1 to promote M2 polarization of macrophages via modulation of the miR-132/Mycbp2/TSC2 axis.
Sun Nov 01 00:00:00 UTC 2020
Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury.
Journal of neuroinflammation
Kong FQ,Zhao SJ,Sun P,Liu H,Jie J,Xu T,Xu AD,Yang YQ,Zhu Y,Chen J,Zhou Z,Qian DF,Gu CJ,Chen Q,Yin GY,Zhang HW,Fan J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Mon Feb 17 00:00:00 UTC 2020
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage.
Nature communications
Chen J,Wang L,Xu H,Xing L,Zhuang Z,Zheng Y,Li X,Wang C,Chen S,Guo Z,Liang Q,Wang Y
12-2061 was used in Flow cytometry/Cell sorting to demonstrate that the meningeal lymphatics drain extravasated erythrocytes from CSF into CLNs after SAH, while suggesting that modulating this draining may offer therapeutic approaches to alleviate SAH severity.
Mon Jun 22 00:00:00 UTC 2020
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage.
Nature communications
Chen J,Wang L,Xu H,Xing L,Zhuang Z,Zheng Y,Li X,Wang C,Chen S,Guo Z,Liang Q,Wang Y
12-2061 was used in Flow cytometry/Cell sorting to demonstrate that the meningeal lymphatics drain extravasated erythrocytes from CSF into CLNs after SAH, while suggesting that modulating this draining may offer therapeutic approaches to alleviate SAH severity.
Mon Jun 22 00:00:00 UTC 2020
Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammation.
JCI insight
Lee HJ,Ko JH,Kim HJ,Jeong HJ,Oh JY
12-2061 was used in Flow cytometry/Cell sorting to reveal that suppression of prostaglandin E2 (PGE2) and HGF secretion in MSCs by siRNA transfection partially reversed the effects of MSCs on MDSC differentiation.
Thu Jun 18 00:00:00 UTC 2020
Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress.
PloS one
Wan YM,Li ZQ,Liu C,He YF,Wang MJ,Wu XN,Zhang Y,Li YH
12-2061-82 was used in Flow Cytometry to investigate whether MSCs are effective in treating mice with alcoholic hepatitis (AH) and its underlying mechanism.
Thu May 07 00:00:00 UTC 2020
Low-Dose Apatinib Optimizes Tumor Microenvironment and Potentiates Antitumor Effect of PD-1/PD-L1 Blockade in Lung Cancer.
Cancer immunology research
Zhao S,Ren S,Jiang T,Zhu B,Li X,Zhao C,Jia Y,Shi J,Zhang L,Liu X,Qiao M,Chen X,Su C,Yu H,Zhou C,Zhang J,Camidge DR,Hirsch FR
12-2061 was used in Flow cytometry/Cell sorting to analyze the impact of apatinib, a smallmolecule VEGFR2-TKI, on the TME in murine Lewis lung carcinoma (LLC) models at different doses alone and in combination with an anti–PD-L1.
Mon Apr 01 00:00:00 UTC 2019
Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models.
Breast cancer research : BCR
Sabol RA,Bowles AC,Côté A,Wise R,O'Donnell B,Matossian MD,Hossain FM,Burks HE,Del Valle L,Miele L,Collins-Burow BM,Burow ME,Bunnell BA
12-2061 was used in Flow cytometry/Cell sorting to study the mechanisms by which obesity promotes tumour progression.
Wed May 22 00:00:00 UTC 2019
Rosiglitazone polarizes microglia and protects against pilocarpine-induced status epilepticus.
CNS neuroscience & therapeutics
Peng J,Wang K,Xiang W,Li Y,Hao Y,Guan Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Sun Dec 01 00:00:00 UTC 2019
Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1.
Frontiers in endocrinology
Loiola RA,Wickstead ES,Solito E,McArthur S
12-2061-82 was used in Flow Cytometry to investigate the role of estrogen following brain tissue injury.
Tue Feb 25 00:00:00 UTC 2020
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Journal for immunotherapy of cancer
Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Nov 28 00:00:00 UTC 2019
Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model.
Translational neurodegeneration
Costa-Marques L,Arnold K,Pardon MC,Leovsky C,Swarbrick S,Fabian C,Stolzing A
12-2061-82 was used in Flow cytometry/Cell sorting to investigate early hallmarks of putative therapeutic effects following systemic transplantation of bone marrow derived macrophages in APP/PS1 transgenic mice.
Mon Apr 11 00:00:00 UTC 2022
Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone.
Journal of neuroinflammation
Yin X,Feng L,Ma D,Yin P,Wang X,Hou S,Hao Y,Zhang J,Xin M,Feng J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Tue Mar 27 00:00:00 UTC 2018
Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE-/- Mice by Skewing Macrophages to the M2 Phenotype.
Frontiers in pharmacology
Guo M,Xiao J,Sheng X,Zhang X,Tie Y,Wang L,Zhao L,Ji X
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2061-82) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2020
Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
JCI insight
Gyori D,Lim EL,Grant FM,Spensberger D,Roychoudhuri R,Shuttleworth SJ,Okkenhaug K,Stephens LR,Hawkins PT
12-2061 was used in Flow cytometry/Cell sorting to study the role of CSF1R dependent TAMs on the immunosuppressive tumour microenvironment.
Thu Jun 07 00:00:00 UTC 2018
PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy.
Scientific reports
Gao S,Li C,Zhu Y,Wang Y,Sui A,Zhong Y,Xie B,Shen X
12-2061 was used in Western Blotting to investigate the protective role of PEDF against retinal neovascularization by regulating macrophage recruitment and polarization.
Fri Feb 17 00:00:00 UTC 2017
PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy.
Scientific reports
Gao S,Li C,Zhu Y,Wang Y,Sui A,Zhong Y,Xie B,Shen X
12-2061 was used in Western Blotting to investigate the protective role of PEDF against retinal neovascularization by regulating macrophage recruitment and polarization.
Fri Feb 17 00:00:00 UTC 2017
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-Flow-20170216130641.jpg?time=20250104?time=20250104 "CD206 (MMR) Antibody (12-2061-82) in Flow")
