Product References
Sustained release of therapeutic gene by injectable hydrogel for hepatocellular carcinoma.
International journal of pharmaceutics: X
Xu S,Cai J,Cheng H,Wang W
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Fri Dec 15 00:00:00 UTC 2023
Contribution of Mesenchymal Stem Cells from Obese Adipose Tissue to PD-L1 Over-Expression and Breast Cancer Progression through Pathogenic Th17 Cell Activation.
Cancers
Blangero F,Robert M,Andraud T,Dumontet C,Vidal H,Eljaafari A
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Mon May 29 00:00:00 UTC 2023
P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8+ T-cell Responses, and Aggravates Oral Cancer.
Cancer immunology research
Ren J,Han X,Lohner H,Hoyle RG,Li J,Liang S,Wang H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2023
AR-A014418 regulates intronic polyadenylation and transcription of PD-L1 through inhibiting CDK12 and CDK13 in tumor cells.
Journal for immunotherapy of cancer
Zhang G,Lan B,Zhang X,Lin M,Liu Y,Chen J,Guo F
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Mon May 01 00:00:00 UTC 2023
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nature communications
Linnerbauer M,Beyer T,Nirschl L,Farrenkopf D,Lößlein L,Vandrey O,Peter A,Tsaktanis T,Kebir H,Laplaud D,Oellinger R,Engleitner T,Alvarez JI,Rad R,Korn T,Hemmer B,Quintana FJ,Rothhammer V
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Sat Sep 09 00:00:00 UTC 2023
BRAF D594A mutation defines a unique biological and immuno-modulatory subgroup associated with functional CD8+ T cell infiltration in colorectal cancer.
Journal of translational medicine
Li W,Zhao C,Li W,Gong Y,Ma K,Lu Y,Liu X,Zhang L,Guo F
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Wed Oct 18 00:00:00 UTC 2023
Combined PARP and WEE1 inhibition triggers anti-tumor immune response in BRCA1/2 wildtype triple-negative breast cancer.
NPJ breast cancer
Teo ZL,O'Connor MJ,Versaci S,Clarke KA,Brown ER,Percy LW,Kuykhoven K,Mintoff CP,Savas P,Virassamy B,Luen SJ,Byrne A,Sant S,Lindeman GJ,Darcy PK,Loi S
25-5982-82 was used in Flow cytometry/Cell sorting to identify baseline tumour-infiltrating lymphocyte (TIL) levels as a potential predictive biomarker of response to PARPi, WEE1i and immunotherapies in BRCA1/2 wild-type TNBC.
Tue Aug 15 00:00:00 UTC 2023
Modification of PLAC8 by UFM1 affects tumorous proliferation and immune response by impacting PD-L1 levels in triple-negative breast cancer.
Journal for immunotherapy of cancer
Mao M,Chen Y,Yang J,Cheng Y,Xu L,Ji F,Zhou J,Zhang X,Li Z,Chen C,Ju S,Zhang J,Wang L
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
Heterogeneity of tyrosine-based melanin anabolism regulates pulmonary and cerebral organotropic colonization microenvironment of melanoma cells.
Theranostics
Wang X,Chen Y,Lan B,Wang Y,Lin W,Jiang X,Ye J,Shang B,Feng C,Liu J,Zhai J,Xu M,Li Q,Lin L,Hu M,Zheng F,Chen L,Shao C,Wang Y,Shi Y
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Thu Apr 21 00:00:00 UTC 2022
Isotope tracing reveals distinct substrate preference in murine melanoma subtypes with differing anti-tumor immunity.
Cancer & metabolism
Zhang X,Halberstam AA,Zhu W,Leitner BP,Thakral D,Bosenberg MW,Perry RJ
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia.
Cancers
Ebelt ND,Manuel ER
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Sun Dec 25 00:00:00 UTC 2022
Impact of mouse model tumor implantation site on acquired resistance to anti-PD-1 immune checkpoint therapy.
Frontiers in immunology
Denis M,Mathé D,Micoud M,Choffour PA,Grasselly C,Matera EL,Dumontet C
25-5982-82 was used in flow cytometry to demonstrate several differences between SC and orthotopic models at basal state, which tend to become similar after therapy.
Tue Jan 31 00:00:00 UTC 2023
Non-synergy of PD-1 blockade with T-cell therapy in solid tumors.
Journal for immunotherapy of cancer
Davies JS,Karimipour F,Zhang L,Nagarsheth N,Norberg S,Serna C,Strauss J,Chiou S,Gulley JL,Hinrichs CS
25-5982-82 was used in Flow cytometry/Cell sorting to support the concept that PD-1 blockade acts primarily through endogenous rather than transferred T cells to mediate a non-synergistic antitumor effect in solid tumor cell therapy.
Fri Jul 01 00:00:00 UTC 2022
Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents.
Journal of nanobiotechnology
Hagemans IM,Wierstra PJ,Steuten K,Molkenboer-Kuenen JDM,van Dalen D,Ter Beest M,van der Schoot JMS,Ilina O,Gotthardt M,Figdor CG,Scheeren FA,Heskamp S,Verdoes M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Wed Feb 02 00:00:00 UTC 2022
Mutant APC promotes tumor immune evasion via PD-L1 in colorectal cancer.
Oncogene
Cen B,Wei J,Wang D,Xiong Y,Shay JW,DuBois RN
25-5982-82 was used in Flow cytometry/Cell sorting to demonstrate that mutations in the adenomatous polyposis coli (APC) gene lead to colonic epithelial cell resistance to CD8+ T cell cytotoxicity by induction of PD-L1 expression.
Fri Oct 01 00:00:00 UTC 2021
Radiation-induced abscopal effect and its enhancement by programmed cell death 1 blockade in the hepatocellular carcinoma: A murine model study.
Clinical and molecular hepatology
Yoo GS,Ahn WG,Kim SY,Kang W,Choi C,Park HC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2021
Oncolytic herpes simplex virus HF10 (canerpaturev) promotes accumulation of CD8+ PD-1- tumor-infiltrating T cells in PD-L1-enriched tumor microenvironment.
International journal of cancer
Eissa IR,Mukoyama N,Abdelmoneim M,Naoe Y,Matsumura S,Bustos-Villalobos I,Ichinose T,Miyajima N,Morimoto D,Tanaka M,Fujimoto Y,Sone M,Kodera Y,Kasuya H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Thu Jul 01 00:00:00 UTC 2021
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.
JCI insight
Ferrere G,Tidjani Alou M,Liu P,Goubet AG,Fidelle M,Kepp O,Durand S,Iebba V,Fluckiger A,Daillère R,Thelemaque C,Grajeda-Iglesias C,Alves Costa Silva C,Aprahamian F,Lefevre D,Zhao L,Ryffel B,Colomba E,Arnedos M,Drubay D,Rauber C,Raoult D,Asnicar F,Spector T,Segata N,Derosa L,Kroemer G,Zitvogel L
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Mon Jan 25 00:00:00 UTC 2021
Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer Leading to Reductions in Immunosuppressive Subsets and Tumor Growth.
Cancers
Ebelt ND,Zamloot V,Zuniga E,Passi KB,Sobocinski LJ,Young CA,Blazar BR,Manuel ER
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Fri Jul 16 00:00:00 UTC 2021
USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade.
Nature communications
Yang Z,Xu G,Wang B,Liu Y,Zhang L,Jing T,Tang M,Xu X,Jiao K,Xiang L,Fu Y,Tang D,Zhang X,Jin W,Zhuang G,Zhao X,Liu Y
25-5982-82 was used in Flow Cytometry to show that the deubiquitinase USP12 is commonly downregulated in the KrasG12D-driven mouse lung tumour and human non-small cell lung cancer owing to the activation of AKT-mTOR signalling.
Wed Aug 11 00:00:00 UTC 2021
USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade.
Nature communications
Yang Z,Xu G,Wang B,Liu Y,Zhang L,Jing T,Tang M,Xu X,Jiao K,Xiang L,Fu Y,Tang D,Zhang X,Jin W,Zhuang G,Zhao X,Liu Y
25-5982-82 was used in Flow Cytometry to show that the deubiquitinase USP12 is commonly downregulated in the KrasG12D-driven mouse lung tumour and human non-small cell lung cancer owing to the activation of AKT-mTOR signalling.
Wed Aug 11 00:00:00 UTC 2021
Antigen-Capturing Mesoporous Silica Nanoparticles Enhance the Radiation-Induced Abscopal Effect in Murine Hepatocellular Carcinoma Hepa1-6 Models.
Pharmaceutics
Yang K,Choi C,Cho H,Ahn WG,Kim SY,Shin SW,Kim Y,Jang T,Lee N,Park HC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Fri Oct 29 00:00:00 UTC 2021
Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity.
Cell reports
Wang Y,Song M,Liu M,Zhang G,Zhang X,Li MO,Ma X,Zhang JJ,Huang XY
25-5982-82 was used in Flow Cytometry to investigate the effects of fascin blockade in anti-tumor immune responses in syngeneic mouse models of various cancers.
Tue Apr 06 00:00:00 UTC 2021
Downregulation of PD-L1 via amide analogues of brefelamide: Alternatives to antibody-based cancer immunotherapy.
Experimental and therapeutic medicine
Zhang J,Yamada O,Kida S,Murase S,Hattori T,Oshima Y,Kikuchi H
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
Genetic ablation of adipocyte PD-L1 reduces tumor growth but accentuates obesity-associated inflammation.
Journal for immunotherapy of cancer
Wu B,Chiang HC,Sun X,Yuan B,Mitra P,Hu Y,Curiel TJ,Li R
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Sat Aug 01 00:00:00 UTC 2020
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
Journal for immunotherapy of cancer
Neuwelt AJ,Kimball AK,Johnson AM,Arnold BW,Bullock BL,Kaspar RE,Kleczko EK,Kwak JW,Wu MH,Heasley LE,Doebele RC,Li HY,Nemenoff RA,Clambey ET
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Sun Nov 01 00:00:00 UTC 2020
GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.
Cancer cell
Mondragón L,Mhaidly R,De Donatis GM,Tosolini M,Dao P,Martin AR,Pons C,Chiche J,Jacquin M,Imbert V,Proïcs E,Boyer L,Doye A,Luciano F,Neels JG,Coutant F,Fabien N,Sormani L,Rubio-Patiño C,Bossowski JP,Muller F,Marchetti S,Villa E,Peyron JF,Gaulard P,Lemonnier F,Asnafi V,Genestier L,Benhida R,Fournié JJ,Passeron T,Ricci JE,Verhoeyen E
25-5982-82 was used in Flow Cytometry to suggest the therapeutic potential of targeting NF-κB signaling in AITL and provide a model for future AITL therapeutic investigations.
Mon Sep 16 00:00:00 UTC 2019
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
Molecular oncology
Zhou Z,Chen H,Xie R,Wang H,Li S,Xu Q,Xu N,Cheng Q,Qian Y,Huang R,Shao Z,Xiang M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Mon Apr 01 00:00:00 UTC 2019
PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy.
The Journal of clinical investigation
Zamarin D,Ricca JM,Sadekova S,Oseledchyk A,Yu Y,Blumenschein WM,Wong J,Gigoux M,Merghoub T,Wolchok JD
25-5982 was used in Flow cytometry/Cell sorting to use human tumour histocultures and syngeneic tumour models treated with Newcastle disease virus to identify immune targets upregulated by OV treatment.
Mon Apr 02 00:00:00 UTC 2018
PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy.
The Journal of clinical investigation
Zamarin D,Ricca JM,Sadekova S,Oseledchyk A,Yu Y,Blumenschein WM,Wong J,Gigoux M,Merghoub T,Wolchok JD
25-5982 was used in Flow cytometry/Cell sorting to use human tumour histocultures and syngeneic tumour models treated with Newcastle disease virus to identify immune targets upregulated by OV treatment.
Mon Apr 02 00:00:00 UTC 2018
PD-1/PD-L1 regulates Treg differentiation in pregnancy-induced hypertension.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Jiang L,Tang C,Gong Y,Liu Y,Rao J,Chen S,Qu W,Wu D,Lei L,Chen L
25-5982 was used in Flow cytometry to study the relationship between PD-1/PD-L1 and regulatory T cell differentiation in pregnancy-induced hypertension.
Mon Jun 25 00:00:00 UTC 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Wed Mar 28 00:00:00 UTC 2018
MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity.
JCI insight
Lee-Sherick AB,Jacobsen KM,Henry CJ,Huey MG,Parker RE,Page LS,Hill AA,Wang X,Frye SV,Earp HS,Jordan CT,DeRyckere D,Graham DK
25-5982 was used in Flow cytometry/Cell sorting to demonstrate both the direct therapeutic effects of MERTK inhibition on leukaemia cells and the induction of anti-leukaemia immunity via suppression of the coinhibitory PD-1 axis.
Fri Nov 02 00:00:00 UTC 2018
Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.
Immunity
Coelho MA,de Carné Trécesson S,Rana S,Zecchin D,Moore C,Molina-Arcas M,East P,Spencer-Dene B,Nye E,Barnouin K,Snijders AP,Lai WS,Blackshear PJ,Downward J
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Tue Dec 19 00:00:00 UTC 2017
Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response.
Scientific reports
Soukup K,Halfmann A,Dillinger B,Poyer F,Martin K,Blauensteiner B,Kauer M,Kuttke M,Schabbauer G,Dohnal AM
25-5982 was used in Flow cytometry/Cell sorting to suggest that MAPK-activated protein kinase 2 deletion leads to an expansion of stimulatory CD103+ dendritic cells, mounting a potent CD8+ T cell anti-tumour response in mice.
Mon Sep 18 00:00:00 UTC 2017
Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.
Oncotarget
Peer S,Baier G,Gruber T
25-5982 was used in Flow cytometry/Cell sorting to show that Cblb-/- T cells are less susceptible to PD-L1-mediated suppression of T cell proliferation and IFNγ secretion.
Tue Jun 27 00:00:00 UTC 2017
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Tue May 17 00:00:00 UTC 2016
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation.
Cell stem cell
Zheng J,Umikawa M,Zhang S,Huynh H,Silvany R,Chen BP,Chen L,Zhang CC
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Fri Aug 05 00:00:00 UTC 2011
Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance.
The Journal of pharmacology and experimental therapeutics
Yang W,Yamada M,Tamura Y,Chang K,Mao J,Zou L,Feng Y,Kida K,Scherrer-Crosbie M,Chao W,Ichinose F,Yu YM,Fischman AJ,Tompkins RG,Yao S,Kaneki M
Published figure using CD274 (PD-L1, B7-H1) monoclonal antibody (Product # 25-5982-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2011
A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1.
Cell research
Sheng H,Wang Y,Jin Y,Zhang Q,Zhang Y,Wang L,Shen B,Yin S,Liu W,Cui L,Li N
Fri Aug 01 00:00:00 UTC 2008
