Invitrogen

CD34 Monoclonal Antibody (4H11), Biotin, eBioscience™

55 Published Figures

46 References

View all (163) CD34 antibodies

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Protocols

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Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)
Published Figures (55)

FIGURE: 1 / 56

CD34 Antibody (13-0349-82) in Flow

Staining of normal human peripheral blood cells with Anti-Human CD45 APC (Product # 17-0459-42) and 0.25 µg of Mouse IgG1 K Isotype Control Biotin (Product # 13-4714-85) (left) or 0.25 µg of Anti-Human CD34 Biotin (right) followed by Streptavidin PE (Product # 12-4317-87). Cells in the lymphocyte gate were used for analysis.

CD34 Antibody in Immunocytochemistry (ICC/IF)

Product Image Gallery

Product Details

13-0349-82

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.5 µg/test

View 42 publications 42 publications

Miscellaneous PubMed (MISC)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Recommended Isotype Control

Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Biotin, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

4H11

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4°C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_10668008

Product Specific Information

Description: The 4H11 monoclonal antibody reacts with human CD34, also known as mucosialin. CD34 belongs to a protein family which also includes endoglycan and podocalyxin. Members of this family are single pass transmembrane proteins with a heavily glycosylated extracellular and N-terminal mucin domain. CD34 was first identified as an antigen expressed on hematopoietic progenitors, and has since been extensively used as a marker to isolate cells capable of hematopoietic cell engraftment. In spite of this, the function of CD34 remains unresolved. In addition to expression on hematopoietic progenitors, CD34 is expressed on some populations of mesenchymal stem cells, tumor cell lines, and by vascular endothelia in the adult. Epitopes of CD34 have been assigned to three classes (class I, II or III) based on their differential sensitivity to enzymatic cleavage by neuraminidase, chymopapain, or O-glycoprotease. According to this analysis, the 4H11 antibody belongs to class III, indicating that it reacts with a protein epitope.

Applications Reported: This 4H11 (APG) antibody has been reported for use in flow cytometric analysis.

Applications Tested: This 4H11 (APG) antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD34 is a highly glycosylated monomeric with a molecular weight range of 111-115 kDa surface protein that is present on many stem cell populations. CD34 is a stem cell marker although its expression on human hematopoietic stem cells is reversible. CD34 may serve as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. CD34 is possibly an adhesion molecule with a putative role for mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Further, CD34 could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Exercise combined with administration of adipose-derived stem cells ameliorates neuropathic pain after spinal cord injury.

Neural regeneration research

Cheng X,Mao GP,Hu WJ,Yu ZR,Xu YY,Chen W,Li X,Zeng XL,Zhang WW,Chen JW,Wan Y,Wang L

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Aug 01 00:00:00 UTC 2023

Celecoxib induces adipogenic differentiation of hemangioma-derived mesenchymal stem cells through the PPAR-γ pathway in vitro and in vivo.

Experimental and therapeutic medicine

Wang Y,Kong L,Sun B,Cui J,Shen W

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed Jun 01 00:00:00 UTC 2022

Angiogenic stem cell delivery platform to augment post-infarction neovasculature and reverse ventricular remodeling.

Scientific reports

Shin HS,Thakore A,Tada Y,Pedroza AJ,Ikeda G,Chen IY,Chan D,Jaatinen KJ,Yajima S,Pfrender EM,Kawamura M,Yang PC,Wu JC,Appel EA,Fischbein MP,Woo Y,Shudo Y

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Thu Oct 20 00:00:00 UTC 2022

Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seq.

Cell discovery

Wang B,Wang C,Wan Y,Gao J,Ma Y,Zhang Y,Tong J,Zhang Y,Liu J,Chang L,Xu C,Shen B,Chen Y,Jiang E,Kurita R,Nakamura Y,Lim KC,Engel JD,Zhou J,Cheng T,Zhu X,Zhu P,Shi L

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue May 10 00:00:00 UTC 2022

Mitochondrial oxidative phosphorylation is dispensable for survival of CD34⁺ chronic myeloid leukemia stem and progenitor cells.

Cell death & disease

Yan JS,Yang MY,Zhang XH,Luo CH,Du CK,Jiang Y,Dong XJ,Wang ZM,Yang LX,Li YD,Xia L,Lu Y

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed Apr 20 00:00:00 UTC 2022

Human placental mesenchymal stem cells regulate inflammation via the NF‑κB signaling pathway.

Experimental and therapeutic medicine

Liu Y,Zhang X,Hu Y,Kang M,Wu Y,Wang Y,Deng C

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Nov 01 00:00:00 UTC 2022

LIM Mineralization Protein-1 Enhances the Committed Differentiation of Dental Pulp Stem Cells through the ERK1/2 and p38 MAPK Pathways and BMP Signaling.

International journal of medical sciences

Mu R,Chen B,Bi B,Yu H,Liu J,Li J,He M,Rong L,Liu B,Liu K,Zhu L,Shi X,Shuai Y,Jin L

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Mon Aug 08 00:00:00 UTC 2022

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.

The Journal of experimental medicine

Louka E,Povinelli B,Rodriguez-Meira A,Buck G,Wen WX,Wang G,Sousos N,Ashley N,Hamblin A,Booth CAG,Roy A,Elliott N,Iskander D,de la Fuente J,Fordham N,O'Byrne S,Inglott S,Norfo R,Salio M,Thongjuea S,Rao A,Roberts I,Mead AJ

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Mon Feb 01 00:00:00 UTC 2021

VAP-PLGA microspheres (VAP-PLGA) promote adipose-derived stem cells (ADSCs)-induced wound healing in chronic skin ulcers in mice via PI3K/Akt/HIF-1α pathway.

Bioengineered

Jiang W,Zhang J,Zhang X,Fan C,Huang J

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed Dec 01 00:00:00 UTC 2021

Endothelial GABBR2 Regulates Post-ischemic Angiogenesis by Inhibiting the Glycolysis Pathway.

Frontiers in cardiovascular medicine

Zhang H,Zhou H,Yuan J,Nan Y,Liu J

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Aug 24 00:00:00 UTC 2021

Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease.

Kidney research and clinical practice

Kim KW,Shin YJ,Kim BM,Cui S,Ko EJ,Lim SW,Yang CW,Chung BH

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Immunocytochemistry

Wed Dec 01 00:00:00 UTC 2021

Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.

NPJ precision oncology

Sugita M,Wilkes DC,Bareja R,Eng KW,Nataraj S,Jimenez-Flores RA,Yan L,De Leon JP,Croyle JA,Kaner J,Merugu S,Sharma S,MacDonald TY,Noorzad Z,Panchal P,Pancirer D,Cheng S,Xiang JZ,Olson L,Van Besien K,Rickman DS,Mathew S,Tam W,Rubin MA,Beltran H,Sboner A,Hassane DC,Chiosis G,Elemento O,Roboz GJ,Mosquera JM,Guzman ML

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed May 26 00:00:00 UTC 2021

TRPA1 triggers hyperalgesia and inflammation after tooth bleaching.

Scientific reports

Chen C,Huang X,Zhu W,Ding C,Huang P,Li R

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Aug 31 00:00:00 UTC 2021

Development, characterization, and hematopoietic differentiation of Griscelli syndrome type 2 induced pluripotent stem cells.

Stem cell research & therapy

Güney-Esken G,Erol ÖD,Pervin B,Gürhan Sevinç G,Önder T,Bilgiç E,Korkusuz P,Günel-Özcan A,Uçkan-Çetinkaya D,Aerts-Kaya F

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Thu May 13 00:00:00 UTC 2021

Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis.

Scientific reports

Køster D,Egedal JH,Lomholt S,Hvid M,Jakobsen MR,Müller-Ladner U,Eibel H,Deleuran B,Kragstrup TW,Neumann E,Nielsen MA

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Fri Nov 12 00:00:00 UTC 2021

Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.

Stem cells international

Zhao AG,Shah K,Freitag J,Cromer B,Sumer H

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Oct 06 00:00:00 UTC 2020

Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.

Molecular medicine reports

Yuan J,Wang X,Ma D,Gao H,Zheng D,Zhang J

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Fri May 01 00:00:00 UTC 2020

Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.

Stem cell research & therapy

Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Fri Nov 27 00:00:00 UTC 2020

Genome-Wide Transcriptional Regulation of the Long Non-coding RNA Steroid Receptor RNA Activator in Human Erythroblasts.

Frontiers in genetics

Sawaengdee W,Cui K,Zhao K,Hongeng S,Fucharoen S,Wongtrakoongate P

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Fri Mar 29 00:00:00 UTC 2024

Chemerin enhances the adhesion and migration of human endothelial progenitor cells and increases lipid accumulation in mice with atherosclerosis.

Lipids in health and disease

Jia J,Yu F,Xiong Y,Wei W,Ma H,Nisi F,Song X,Yang L,Wang D,Yuan G,Zhou H

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Sun Sep 20 00:00:00 UTC 2020

The downregulated membrane expression of CD18 in CD34⁺ cells defines a primitive population of human hematopoietic stem cells.

Stem cell research & therapy

Mesa-Núñez C,Leon-Rico D,Aldea M,Damián C,Sanchez-Baltasar R,Sanchez R,Alberquilla O,Segovia JC,Bueren JA,Almarza E

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Apr 28 00:00:00 UTC 2020

Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.

Stem cells international

Sun B,Luo X,Yang C,Liu P,Yang Y,Dong X,Yang Z,Xu J,Zhang Y,Li L

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Thu May 13 00:00:00 UTC 2021

TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production.

Molecular medicine reports

Fan C,Ji Q,Zhang C,Xu S,Sun H,Li Z

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Oct 01 00:00:00 UTC 2019

Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis.

Nature communications

Kidoya H,Muramatsu F,Shimamura T,Jia W,Satoh T,Hayashi Y,Naito H,Kunisaki Y,Arai F,Seki M,Suzuki Y,Osawa T,Akira S,Takakura N

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed Mar 06 00:00:00 UTC 2019

Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer.

Cancers

Huang JY,Wang YY,Lo S,Tseng LM,Chen DR,Wu YC,Hou MF,Yuan SF

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Fri Dec 20 00:00:00 UTC 2019

Efficient gene transfer into T lymphocytes by fiber-modified human adenovirus 5.

BMC biotechnology

Lv Y,Xiao FJ,Wang Y,Zou XH,Wang H,Wang HY,Wang LS,Lu ZZ

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed Apr 24 00:00:00 UTC 2019

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.

Developmental cell

Böiers C,Richardson SE,Laycock E,Zriwil A,Turati VA,Brown J,Wray JP,Wang D,James C,Herrero J,Sitnicka E,Karlsson S,Smith AJH,Jacobsen SEW,Enver T

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Mon Feb 05 00:00:00 UTC 2018

Human umbilical cord-derived mesenchymal stem cells ameliorate the enteropathy of food allergies in mice.

Experimental and therapeutic medicine

Yan N,Xu J,Zhao C,Wu Y,Gao F,Li C,Zhou W,Xiao T,Zhou X,Shao Q,Xia S

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Sat Dec 01 00:00:00 UTC 2018

Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome.

Stem cell research & therapy

Liu FD,Tam K,Pishesha N,Poon Z,Van Vliet KJ

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed Oct 24 00:00:00 UTC 2018

Combined inhibition of β-catenin and Bcr-Abl synergistically targets tyrosine kinase inhibitor-resistant blast crisis chronic myeloid leukemia blasts and progenitors in vitro and in vivo.

Leukemia

Zhou H,Mak PY,Mu H,Mak DH,Zeng Z,Cortes J,Liu Q,Andreeff M,Carter BZ

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Miscellaneous

Sun Oct 01 00:00:00 UTC 2017

Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells.

Stem cells (Dayton, Ohio)

Yang CT,Ma R,Axton RA,Jackson M,Taylor AH,Fidanza A,Marenah L,Frayne J,Mountford JC,Forrester LM

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Sat Apr 01 00:00:00 UTC 2017

A high-yield isolation and enrichment strategy for human lung microvascular endothelial cells.

Pulmonary circulation

Gaskill C,Majka SM

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed Mar 01 00:00:00 UTC 2017

Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism.

Stem cell research & therapy

Li J,Mao Q,He J,She H,Zhang Z,Yin C

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Thu Mar 09 00:00:00 UTC 2017

Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages.

Stem cell reports

Buchrieser J,James W,Moore MD

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Feb 14 00:00:00 UTC 2017

Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats.

Stem cell research & therapy

Yang H,Wu S,Feng R,Huang J,Liu L,Liu F,Chen Y

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Nov 21 00:00:00 UTC 2017

Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.

Stem cells translational medicine

Jackson M,Ma R,Taylor AH,Axton RA,Easterbrook J,Kydonaki M,Olivier E,Marenah L,Stanley EG,Elefanty AG,Mountford JC,Forrester LM

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Mon Aug 01 00:00:00 UTC 2016

A Member of the Nuclear Receptor Superfamily, Designated as NR2F2, Supports the Self-Renewal Capacity and Pluripotency of Human Bone Marrow-Derived Mesenchymal Stem Cells.

Stem cells international

Zhu N,Wang H,Wang B,Wei J,Shan W,Feng J,Huang H

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Jan 19 00:00:00 UTC 2016

CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa.

NPJ Regenerative medicine

Webber BR,Osborn MJ,McElroy AN,Twaroski K,Lonetree CL,DeFeo AP,Xia L,Eide C,Lees CJ,McElmurry RT,Riddle MJ,Kim CJ,Patel DD,Blazar BR,Tolar J

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Wed Sep 30 00:00:00 UTC 2020

A Simplified Method for the Aspiration of Bone Marrow from Patients Undergoing Hip and Knee Joint Replacement for Isolating Mesenchymal Stem Cells and In Vitro Chondrogenesis.

Bone marrow research

Juneja SC,Viswanathan S,Ganguly M,Veillette C

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Fri Apr 08 00:00:00 UTC 2016

Microvesicles from Mesenchymal Stromal Cells Are Involved in HPC-Microenvironment Crosstalk in Myelodysplastic Patients.

PloS one

Muntión S,Ramos TL,Diez-Campelo M,Rosón B,Sánchez-Abarca LI,Misiewicz-Krzeminska I,Preciado S,Sarasquete ME,de Las Rivas J,González M,Sánchez-Guijo F,Del Cañizo MC

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Jul 12 00:00:00 UTC 2016

Microvesicles from Mesenchymal Stromal Cells Are Involved in HPC-Microenvironment Crosstalk in Myelodysplastic Patients.

PloS one

Muntión S,Ramos TL,Diez-Campelo M,Rosón B,Sánchez-Abarca LI,Misiewicz-Krzeminska I,Preciado S,Sarasquete ME,de Las Rivas J,González M,Sánchez-Guijo F,Del Cañizo MC

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Jul 12 00:00:00 UTC 2016

Functional plasticity of the N-methyl-d-aspartate receptor in differentiating human erythroid precursor cells.

American journal of physiology. Cell physiology

Hänggi P,Telezhkin V,Kemp PJ,Schmugge M,Gassmann M,Goede JS,Speer O,Bogdanova A

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Mon Jun 15 00:00:00 UTC 2015

Differences in the Osteogenic Differentiation Capacity of Omental Adipose-Derived Stem Cells in Obese Patients With and Without Metabolic Syndrome.

Endocrinology

Oliva-Olivera W,Leiva Gea A,Lhamyani S,Coín-Aragüez L,Alcaide Torres J,Bernal-López MR,García-Luna PP,Morales Conde S,Fernández-Veledo S,El Bekay R,Tinahones FJ

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Tue Dec 01 00:00:00 UTC 2015

Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells.

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Han L,Qiu P,Zeng Z,Jorgensen JL,Mak DH,Burks JK,Schober W,McQueen TJ,Cortes J,Tanner SD,Roboz GJ,Kantarjian HM,Kornblau SM,Guzman ML,Andreeff M,Konopleva M

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Miscellaneous

Wed Apr 01 00:00:00 UTC 2015

Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.

Nature

Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Thu Jul 17 00:00:00 UTC 2014

JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo.

Blood

Gallipoli P,Cook A,Rhodes S,Hopcroft L,Wheadon H,Whetton AD,Jørgensen HG,Bhatia R,Holyoake TL

Published figure using CD34 monoclonal antibody (Product # 13-0349-82) in Flow Cytometry

Thu Aug 28 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: CD34; CD34 antigen; Hematopoietic progenitor cell antigen CD34; Mucosialin; RP11-328D5.2

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Gene Aliases: CD34

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UniProt ID: (Human) P28906

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Entrez Gene ID: (Human) 947

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Function(s)

transcription factor binding carbohydrate binding sulfate binding

Process(es)

tissue homeostasis endothelial cell proliferation glomerular filtration endothelium development cell-matrix adhesion signal transduction regulation of blood pressure cell proliferation positive regulation of gene expression negative regulation of gene expression single organismal cell-cell adhesion hemopoiesis negative regulation of blood coagulation negative regulation of tumor necrosis factor production positive regulation of interleukin-10 production mesangial cell-matrix adhesion paracrine signaling positive regulation of odontogenesis negative regulation of nitric oxide biosynthetic process positive regulation of angiogenesis cell motility regulation of immune response leukocyte migration transdifferentiation vascular wound healing hematopoietic stem cell proliferation positive regulation of transforming growth factor beta production positive regulation of granulocyte colony-stimulating factor production extracellular exosome assembly glomerular endothelium development stem cell proliferation metanephric glomerular mesangial cell differentiation negative regulation of cellular response to heat negative regulation of cellular response to hypoxia negative regulation of interleukin-2 secretion positive regulation of glial cell-derived neurotrophic factor secretion negative regulation of neuron death positive regulation of vasculogenesis

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CD34 Monoclonal Antibody (4H11), Biotin, eBioscience™

CD34 Antibody (13-0349-82) in Flow

Product Details

13-0349-82

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Miscellaneous PubMed (MISC)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

Class

Type

Clone

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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