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Mouse anti Sheep CD41/CD61 antibody, clone CO.35E4 recognizes ruminant CD41/CD61, also known as GpIIb/IIIa. CD41/CD61 is a calcium-complex dependent heterodimer and is expressed almost exclusively on platelets and on their precursors, the megakaryocytes.
CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD61 non-covalently associates with CD41.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glycoprotein GPIIb; glycoprotein GPIIIa; glycoprotein IIb; glycoprotein IIIa; integrin alpha 2b; Integrin alpha-2b; integrin alpha-IIb; integrin beta-3; integrin beta-3 subunit; integrin beta3; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); platelet glycoprotein IIb; platelet glycoprotein IIIa integrin subunit beta 3
Gene Aliases: BOS_19272; BOS_19317; GPIIB; GPIIIA; INTB3; Itgb3
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