Invitrogen

CD41/CD61 Monoclonal Antibody (IVA30)

View all (9) CD41/CD61 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

MA1-19303

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

Assay-dependent
-

Flow Cytometry (Flow)

1-4 µg/mL
-

ELISA (ELISA)

Assay-dependent
-

Immunoprecipitation (IP)

Assay-dependent
-
Product Specifications

Species Reactivity

Bovine, Human

Host/Isotype

Mouse / IgG2

Class

Monoclonal

Type

Antibody

Clone

IVA30

Immunogen

Bovine trombocytes.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.0 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2291529

Product Specific Information

This antibody reacts with human platelets.

Target Information

CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD61 non-covalently associates with CD41.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: alphaIIb protein; antigen CD61; CD41; CD61; GPalpha IIb; GPIIb; GPIIIa; integrin alpha 2b; Integrin alpha-2b; Integrin alpha-IIb; integrin beta 3; Integrin beta-3; integrin beta-3 subunit; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet membrane glycoprotein IIIa; platelet-specific antigen BAK; protein phosphatase 1, regulatory subunit 93

View more View less

Gene Aliases: BDPLT16; BDPLT2; BOS_19272; BOS_19317; CD41; CD41B; CD61; GP2B; GP3A; GPIIb; GPIIIa; GT; GTA; HPA3; INTB3; ITGA2B; ITGAB; ITGB3; PPP1R93

View more View less

UniProt ID: (Human) P08514, (Human) P05106

View more View less

Entrez Gene ID: (Human) 3674, (Bovine) 515011, (Human) 3690, (Bovine) 282642

View more View less

Function(s)
protein binding identical protein binding metal ion binding extracellular matrix binding fibrinogen binding virus receptor activity fibronectin binding protease binding protein disulfide isomerase activity platelet-derived growth factor receptor binding coreceptor activity fibroblast growth factor binding enzyme binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding vascular endothelial growth factor receptor 2 binding cell adhesion molecule binding
Process(es)
platelet degranulation positive regulation of leukocyte migration cell adhesion cell-matrix adhesion integrin-mediated signaling pathway extracellular matrix organization platelet aggregation positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation cell-substrate junction assembly blood coagulation positive regulation of endothelial cell migration negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage smooth muscle cell migration cell growth cell migration platelet activation positive regulation of vascular endothelial growth factor receptor signaling pathway cell-substrate adhesion activation of protein kinase activity negative regulation of lipid transport heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading tube development apolipoprotein A-I-mediated signaling pathway wound healing regulation of bone resorption negative regulation of low-density lipoprotein particle receptor biosynthetic process viral entry into host cell vascular endothelial growth factor receptor signaling pathway mesodermal cell differentiation positive regulation of peptidyl-tyrosine phosphorylation negative regulation of lipoprotein metabolic process leukocyte migration negative chemotaxis angiogenesis involved in wound healing
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support