Product References
MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.
Cancer discovery
Sodir NM,Kortlever RM,Barthet VJA,Campos T,Pellegrinet L,Kupczak S,Anastasiou P,Swigart LB,Soucek L,Arends MJ,Littlewood TD,Evan GI
MA1-70098 was used in Immunohistochemistry to demonstrate that this Myc-driven PDAC switch is completely and immediately reversible: Myc deactivation/inhibition triggers meticulous disassembly of advanced PDAC tumor and stroma and concomitant death of tumor cells.
Wed Apr 01 00:00:00 UTC 2020
DNA-PK Is Targeted by Multiple Vaccinia Virus Proteins to Inhibit DNA Sensing.
Cell reports
Scutts SR,Ember SW,Ren H,Ye C,Lovejoy CA,Mazzon M,Veyer DL,Sumner RP,Smith GL
MA1-70098 was used in Flow cytometry/Cell sorting to describe the roles and interactions of vaccinia virus proteins C4 and C16 in inhibiting host DNA-PK during infection.
Tue Nov 13 00:00:00 UTC 2018
Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.
Cell
Kortlever RM,Sodir NM,Wilson CH,Burkhart DL,Pellegrinet L,Brown Swigart L,Littlewood TD,Evan GI
Published figure using CD45R monoclonal antibody (Product # MA1-70098) in Immunohistochemistry
Thu Nov 30 00:00:00 UTC 2017
SMN deficiency negatively impacts red pulp macrophages and spleen development in mouse models of spinal muscular atrophy.
Human molecular genetics
Khairallah MT,Astroski J,Custer SK,Androphy EJ,Franklin CL,Lorson CL
MA1-70098 was used in Immunohistochemistry to analyze the spleen and immunological components in Spinal muscular atrophy (SMA) mice, with a focus on the effects of reduced Survival Motor Neuron (SMN) protein.
Wed Mar 01 00:00:00 UTC 2017
Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment.
Nature immunology
Zhong C,Cui K,Wilhelm C,Hu G,Mao K,Belkaid Y,Zhao K,Zhu J
MA170098 was used in flow cytometry to explore the contributions of GATA3 to the group 3 innate lymphoid cells
Mon Feb 01 00:00:00 UTC 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
MA170098 was used in flow cytometry to study the contribution of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer cell activation and tumor control
Wed Jun 01 00:00:00 UTC 2016
In vitro Differentiation of Murine Innate Lymphoid Cells from Common Lymphoid Progenitor Cells.
Bio-protocol
Seehus C,Kaye J
MA170098 was used in flow cytometry to detail how to obtain innate lymphoid cells from isolated common lymphoid progenitors
Sun Mar 20 00:00:00 UTC 2016
Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23.
Mucosal immunology
Donaldson DS,Bradford BM,Artis D,Mabbott NA
MA1-70098 was used in immunohistochemistry to assess IL-25 and IL-23 and reciprocal regulation of lymphoid tissue development in the large intestine
Fri May 01 00:00:00 UTC 2015
KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice.
PLoS pathogens
Sin SH,Kim Y,Eason A,Dittmer DP
MA1-70098 was used in flow cytometry to study lymphoma in mice driven by Myc cooperating with the KSHV latency locus
Tue Sep 01 00:00:00 UTC 2015
Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation.
PLoS pathogens
Sei JJ,Haskett S,Kaminsky LW,Lin E,Truckenmiller ME,Bellone CJ,Buller RM,Norbury CC
MA170098 was used in immunohistochemistry to parse the relative importance of the direct and indirect antigen presentation pathways in ectromelia virus mouse pox infection.
Mon Jun 01 00:00:00 UTC 2015
The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis.
Journal of virology
Donaldson DS,Else KJ,Mabbott NA
MA1-70098 was used in immunohistochemistry to characterize oral prion disease pathogenesis and gut-associated lymphoid tissues in the small intestine and not the large intestine
Tue Sep 01 00:00:00 UTC 2015
Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice.
Journal of virology
Morales DJ,Monte K,Sun L,Struckhoff JJ,Agapov E,Holtzman MJ,Stappenbeck TS,Lenschow DJ
MA1-70098 was used in flow cytometry to describe the pathogenesis of influenza A virus and Sendai virus in ISG15 knockout mice
Thu Jan 01 00:00:00 UTC 2015
Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans.
Journal of immunology (Baltimore, Md. : 1950)
Schulz AR,Mälzer JN,Domingo C,Jürchott K,Grützkau A,Babel N,Nienen M,Jelinek T,Niedrig M,Thiel A
MA1-70098 was used in flow cytometry to study age-related changes in human immunity during a primary virus infection experimentally induced by immunization with live-attenuated yellow fever vaccine
Sun Nov 15 00:00:00 UTC 2015
Functional classification of memory CD8(+) T cells by CX3CR1 expression.
Nature communications
Böttcher JP,Beyer M,Meissner F,Abdullah Z,Sander J,Höchst B,Eickhoff S,Rieckmann JC,Russo C,Bauer T,Flecken T,Giesen D,Engel D,Jung S,Busch DH,Protzer U,Thimme R,Mann M,Kurts C,Schultze JL,Kastenmüller W,Knolle PA
MA1-70098 was used in immunohistochemistry - frozen section to analyze CX3CR1 expression and functional classification of memory CD8(+) T cells
Fri Sep 25 00:00:00 UTC 2015
The proximal J kappa germline-transcript promoter facilitates receptor editing through control of ordered recombination.
PloS one
Vettermann C,Timblin GA,Lim V,Lai EC,Schlissel MS
MA1-70098 was used in flow cytometry to analyze how ordered recombination occurs through the proximal J kappa germline-transcript promoter facilitating receptor editing
Tue Jan 26 00:00:00 UTC 2016
T cells generated in the absence of a thoracic thymus fail to establish homeostasis.
European journal of immunology
Smolarchuk C,Zhu LF,Chan WF,Anderson CC
MA1-70098 was used in flow cytometry to investigate the role of thoracic thymus in T cell development and homeostasis
Fri Aug 01 00:00:00 UTC 2014
Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response.
Journal of immunology (Baltimore, Md. : 1950)
Hu J,Oda SK,Shotts K,Donovan EE,Strauch P,Pujanauski LM,Victorino F,Al-Shami A,Fujiwara Y,Tigyi G,Oravecz T,Pelanda R,Torres RM
MA1-70098 was used in Flow Cytometry to reveal that alterations in lysophosphatidic acid levels likely influence adaptive humoural immunity.
Tue Jul 01 00:00:00 UTC 2014
Generation of eosinophils from cryopreserved murine bone marrow cells.
PloS one
Schollaert KL,Stephens MR,Gray JK,Fulkerson PC
MA1-70098 was used in flow cytometry to develop a culture system to grow functional eosinophils from bone marrow progenitors
Thu Oct 01 00:00:00 UTC 2015
The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice.
Mucosal immunology
Kobayashi A,Donaldson DS,Erridge C,Kanaya T,Williams IR,Ohno H,Mahajan A,Mabbott NA
MA1-70098 was used in immunohistochemistry - frozen section to report the effects of aging on maturation of M cells
Sun Sep 01 00:00:00 UTC 2013
Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells.
Immunology letters
Fuertbauer E,Zaujec J,Uhrin P,Raab I,Weber M,Schachner H,Bauer M,Schütz GJ,Binder BR,Sixt M,Kerjaschki D,Stockinger H
MA1-70098 was used in flow cytometry to characterize mice deficient in podoplanin and explore the effect of podoplanin modulation on T cell populations.
Mon Jul 14 00:00:00 UTC 2014
Consequences of the combined loss of BOK and BAK or BOK and BAX.
Cell death & disease
Ke F,Bouillet P,Kaufmann T,Strasser A,Kerr J,Voss AK
MA1-70098 was used in flow cytometry to determine if Bok and Bax have any functional redundancy controlling apoptosis using knock out mice.
Thu Jun 06 00:00:00 UTC 2013
CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.
Journal of immunology (Baltimore, Md. : 1950)
Wensveen FM,Unger PP,Kragten NA,Derks IA,ten Brinke A,Arens R,van Lier RA,Eldering E,van Gisbergen KP
MA1-70098 was used in Flow Cytometry to investigate how BIm-dependent apoptosis is initiated in CD8 T cells.
Tue May 01 00:00:00 UTC 2012
Involvement of lymphocyte infiltration in the progression of mouse peritoneal fibrosis model.
Renal failure
Nishino T,Ashida R,Obata Y,Furusu A,Abe K,Miyazaki M,Koji T,Kohno S
MA1-70098 was used in immunohistochemistry (paraffin) to assess the role of lymphocytes in the development of peritoneal fibrosis induced by chlorhexidine gluconate.
Wed Oct 24 00:00:00 UTC 2012
Dominant Role of CD80-CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T Cells.
Frontiers in immunology
Chevrier S,Genton C,Malissen B,Malissen M,Acha-Orbea H
MA1-70098 was used in immunohistochemistry - frozen section to suggest that CD80 and CD86 contribute to polyclonal B cell activation mediated by Lat(Y136F) CD4 positive T cells
Thu Aug 23 00:00:00 UTC 2012
DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice.
The Journal of experimental medicine
Randall KL,Chan SS,Ma CS,Fung I,Mei Y,Yabas M,Tan A,Arkwright PD,Al Suwairi W,Lugo Reyes SO,Yamazaki-Nakashimada MA,Garcia-Cruz Mde L,Smart JM,Picard C,Okada S,Jouanguy E,Casanova JL,Lambe T,Cornall RJ,Russell S,Oliaro J,Tangye SG,Bertram EM,Goodnow CC
MA1-70098 was used in flow cytometry to determine the role for DOCK8 in peripheral CD8 T cell survival and function
Mon Oct 24 00:00:00 UTC 2011
Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome.
The Journal of allergy and clinical immunology
Bosticardo M,Draghici E,Schena F,Sauer AV,Fontana E,Castiello MC,Catucci M,Locci M,Naldini L,Aiuti A,Roncarolo MG,Poliani PL,Traggiai E,Villa A
MA1-70098 was used in immunohistochemistry - paraffin section to test a gene therapy treatment for Wiskott-Aldrich syndrome for clinical efficacy and safety.
Wed Jun 01 00:00:00 UTC 2011
Gfi1 integrates progenitor versus granulocytic transcriptional programming.
Blood
Horman SR,Velu CS,Chaubey A,Bourdeau T,Zhu J,Paul WE,Gebelein B,Grimes HL
MA1-70098 was used in flow cytometry to report that Gfi1 suppresses the HoxA9-Pbx1-Meis1 progenitor program and induces a granulopoietic transcription program
Thu May 28 00:00:00 UTC 2009
Conventional bone marrow-derived dendritic cells contribute to toll-like receptor-independent production of alpha/beta interferon in response to inactivated parapoxvirus ovis.
Journal of virology
Siegemund S,Hartl A,von Buttlar H,Dautel F,Raue R,Freudenberg MA,Fejer G,Büttner M,Köhler G,Kirschning CJ,Sparwasser T,Alber G
MA1-70098 was used in flow cytometry to study the effect of inactivated Parapoxvirus ovis on dendritic cells
Tue Sep 01 00:00:00 UTC 2009
A defect in Marco expression contributes to systemic lupus erythematosus development via failure to clear apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950)
Rogers NJ,Lees MJ,Gabriel L,Maniati E,Rose SJ,Potter PK,Morley BJ
MA1-70098 was used in flow cytometry to describe a role for Marco in the development of disease in BXSB mice
Sun Feb 15 00:00:00 UTC 2009
A gene-dosage effect for interleukin-4 receptor alpha-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis.
The Journal of infectious diseases
Müller U,Stenzel W,Köhler G,Polte T,Blessing M,Mann A,Piehler D,Brombacher F,Alber G
MA1-70098 was used in flow cytometry to determine the role of IL-4Ralpha to pulmonary C. neoformans infection
Mon Dec 01 00:00:00 UTC 2008
Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity.
Journal of immunology (Baltimore, Md. : 1950)
Wells JW,Cowled CJ,Farzaneh F,Noble A
MA1-70098 was used in flow cytometry to identify key signals required for the exponential expansion of specific CD8 positive mouse T cells in vivo
Mon Sep 01 00:00:00 UTC 2008
An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus.
Arthritis and rheumatism
Bahjat FR,Pine PR,Reitsma A,Cassafer G,Baluom M,Grillo S,Chang B,Zhao FF,Payan DG,Grossbard EB,Daikh DI
MA1-70098 was used in immunohistochemistry - frozen section to test if an inhibitor of spleen tyrosine kinase-dependent signaling modulates disease in a mouse model of lupus via inhibition of Fc receptor and B cell receptor signaling
Thu May 01 00:00:00 UTC 2008
In vivo imaging of germinal centres reveals a dynamic open structure.
Nature
Schwickert TA,Lindquist RL,Shakhar G,Livshits G,Skokos D,Kosco-Vilbois MH,Dustin ML,Nussenzweig MC
MA1-70098 was used in immunohistochemistry - frozen section to visualize B cells in lymph node germinal centers in vivo
Thu Mar 01 00:00:00 UTC 2007
B-lymphocyte depletion ameliorates Sjögren's syndrome in Id3 knockout mice.
Immunology
Hayakawa I,Tedder TF,Zhuang Y
MA1-70098 was used in flow cytometry to investigate the role of B cells in Sjogren's syndrome in a mouse model
Sat Sep 01 00:00:00 UTC 2007
Overexpression of IL-21 promotes massive CD8+ memory T cell accumulation.
European journal of immunology
Allard EL,Hardy MP,Leignadier J,Marquis M,Rooney J,Lehoux D,Labrecque N
MA1-70098 was used in flow cytometry to test the influences of IL-21 on cytokine receptor expression
Thu Nov 01 00:00:00 UTC 2007
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950)
Müller U,Stenzel W,Köhler G,Werner C,Polte T,Hansen G,Schütze N,Straubinger RK,Blessing M,McKenzie AN,Brombacher F,Alber G
MA1-70098 was used in flow cytometry to determine the role of the Th2 cytokine IL-13 during pulmonary infection with C. neoformans
Mon Oct 15 00:00:00 UTC 2007
B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity.
Journal of immunology (Baltimore, Md. : 1950)
Yanaba K,Hamaguchi Y,Venturi GM,Steeber DA,St Clair EW,Tedder TF
MA1-70098 was used in flow cytometry determine the roles of B cells in inflammatory arthritis
Sun Jul 15 00:00:00 UTC 2007
Antibody class switching differs among SJL, C57BL/6 and 129 mice.
International immunology
Kaminski DA,Stavnezer J
MA1-70098 was used in flow cytometry to compare Ig class switching in different inbred mice
Sun Apr 01 00:00:00 UTC 2007
IgE enhances specific antibody and T-cell responses in mice overexpressing CD23.
Scandinavian journal of immunology
Carlsson F,Hjelm F,Conrad DH,Heyman B
MA1-70098 was used in flow cytometry and immunohistochemistry to investigate if IgE enhances antibody and T-cell responses in IgE receptor CD23 transgenic animals or if CD23's downregulatory effect precludes IgE-mediated enhancement
Fri Sep 14 00:00:00 UTC 2007
Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase.
Blood
Gupta R,Karpatkin S,Basch RS
MA1-70098 was used in flow cytometry to investigate how peroxide affects hematopoiesis
Wed Mar 01 00:00:00 UTC 2006
Gut ischemia-reperfusion affects gut mucosal immunity: a possible mechanism for infectious complications after severe surgical insults.
Critical care medicine
Fukatsu K,Sakamoto S,Hara E,Ueno C,Maeshima Y,Matsumoto I,Mochizuki H,Hiraide H
MA1-70098 was used in flow cytometry to determine the influence of gut ischemia/reperfusion on gut-associated lymphoid tissue mass and function
Sun Jan 01 00:00:00 UTC 2006
Revisiting the specificity of the MHC class II transactivator CIITA in vivo.
European journal of immunology
Otten LA,Leibundgut-Landmann S,Huarte J,Kos-Braun IC,Lavanchy C,Barras E,Borisch B,Steimle V,Acha-Orbea H,Reith W
MA1-70098 was used in flow cytometry to identify and study CIITA-regulated genes
Thu Jun 01 00:00:00 UTC 2006
TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire.
European journal of immunology
Silver K,Ferry H,Crockford T,Cornall RJ
MA1-70098 was used in flow cytometry to demonstrate that the effects of Toll-like receptors on autoimmunity occur in the established repertoire and not during B cell development
Thu Jun 01 00:00:00 UTC 2006
Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells.
Journal of immunology (Baltimore, Md. : 1950)
Kaminski DA,Stavnezer J
MA1-70098 was used in flow cytometry to investigate IgA production by different B cell subsets
Wed Nov 01 00:00:00 UTC 2006
Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.
Blood
Iwasaki H,Somoza C,Shigematsu H,Duprez EA,Iwasaki-Arai J,Mizuno S,Arinobu Y,Geary K,Zhang P,Dayaram T,Fenyus ML,Elf S,Chan S,Kastner P,Huettner CS,Murray R,Tenen DG,Akashi K
MA1-70098 was used in flow cytometry to investigate the distinct roles that PU.1 plays in hematopoietic development
Thu Sep 01 00:00:00 UTC 2005
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.
Blood
Growney JD,Shigematsu H,Li Z,Lee BH,Adelsperger J,Rowan R,Curley DP,Kutok JL,Akashi K,Williams IR,Speck NA,Gilliland DG
MA1-70098 was used in flow cytometry to use transgenic mice to investigate the contribution of role of Runx1 to hematopoiesis
Fri Jul 15 00:00:00 UTC 2005
Identification of eosinophil lineage-committed progenitors in the murine bone marrow.
The Journal of experimental medicine
Iwasaki H,Mizuno S,Mayfield R,Shigematsu H,Arinobu Y,Seed B,Gurish MF,Takatsu K,Akashi K
MA1-70098 was used in flow cytometry to elucidate the cellular mechanisms by which granulocyte/monocyte progenitors give rise to eosinophils
Mon Jun 20 00:00:00 UTC 2005
Central nervous system pathology caused by autoreactive CD8+ T-cell clones following virus infection.
Journal of virology
Tsunoda I,Kuang LQ,Kobayashi-Warren M,Fujinami RS
MA1-70098 was used in flow cytometry to characterize T cells from mice infected with Theiler's murine encephalomyelitis virus
Thu Dec 01 00:00:00 UTC 2005
The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Lu M,Tayu R,Ikawa T,Masuda K,Matsumoto I,Mugishima H,Kawamoto H,Katsura Y
MA1-70098 was used in flow cytometry to study T cell progenitors in the adult thymus
Tue Nov 01 00:00:00 UTC 2005
The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice.
Journal of immunology (Baltimore, Md. : 1950)
Hamaguchi Y,Uchida J,Cain DW,Venturi GM,Poe JC,Haas KM,Tedder TF
MA1-70098 was used in flow cytometry and immunohistochemistry - frozen section to determine the effect of anti-CD20 immunotherapy on tissue B cells in vivo
Fri Apr 01 00:00:00 UTC 2005
Effect of thermal injury on splenic myelopoiesis.
Shock (Augusta, Ga.)
Noel JG,Guo X,Wells-Byrum D,Schwemberger S,Caldwell CC,Ogle CK
MA1-70098 was used in flow cytometry to measure the number of splenic myeloid progenitors and their progeny after burn injury
Tue Feb 01 00:00:00 UTC 2005
The CD45 isoform B220 identifies select subsets of human B cells and B-cell lymphoproliferative disorders.
Human pathology
Rodig SJ,Shahsafaei A,Li B,Dorfman DM
MA1-70098 was used in flow cytometry and immunohistochemistry (paraffin) to study B220 in human B cell disorders.
Sat Jan 01 00:00:00 UTC 2005
APS, an adaptor molecule containing PH and SH2 domains, has a negative regulatory role in B cell proliferation.
Biochemical and biophysical research communications
Iseki M,Kubo-Akashi C,Kwon SM,Yamaguchi A,Takatsu K,Takaki S
MA1-70098 was used in flow cytometry to use transgenic mice to study the functions of APS in B cell development and activation
Fri May 13 00:00:00 UTC 2005
Dendritic cell expansion occurs in mesenteric lymph nodes of B10.BR mice infected with the murine nematode parasite Trichuris muris.
Parasitology research
Koyama K
MA1-70098 was used in flow cytometry to characterize dendritic cells in mice infected with Trichuris muris
Sat Oct 01 00:00:00 UTC 2005
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C.
Nature cell biology
Yuan Y,Shen H,Franklin DS,Scadden DT,Cheng T
MA1-70098 was used in flow cytometry to demonstrate that deletion p18(INK4C) results in improved long-term engraftment
Sat May 01 00:00:00 UTC 2004
A cell-surface molecule selectively expressed on murine natural interferon-producing cells that blocks secretion of interferon-alpha.
Blood
Blasius A,Vermi W,Krug A,Facchetti F,Cella M,Colonna M
MA1-70098 was used in immunohistochemistry (frozen) to describe a monoclonal antibody that exclusively detects murine interferon-producing cells.
Tue Jun 01 00:00:00 UTC 2004
Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation.
Blood
Chen BJ,Cui X,Sempowski GD,Domen J,Chao NJ
MA1-70098 was used in flow cytometry to test if higher numbers of hematopoietic stem cells correlate with the speed of immune reconstitution in a congenic transplantation mouse model
Tue Jun 01 00:00:00 UTC 2004
CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion.
The Journal of experimental medicine
Herman AE,Freeman GJ,Mathis D,Benoist C
MA1-70098 was used in flow cytometry to investigate the role of ICOS in regulating the function of T regulatory cells present in autoimmune lesions
Mon Jun 07 00:00:00 UTC 2004
Targeting of secretory IgA to Peyer's patch dendritic and T cells after transport by intestinal M cells.
Journal of immunology (Baltimore, Md. : 1950)
Rey J,Garin N,Spertini F,Corthésy B
MA1-70098 was used in immunohistochemistry (frozen) to study secretory IgA sampling.
Mon Mar 01 00:00:00 UTC 2004
Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: high level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow.
Journal of immunology (Baltimore, Md. : 1950)
Lian ZX,Kikuchi K,Yang GX,Ansari AA,Ikehara S,Gershwin ME
MA1-70098 was used in flow cytometry to elucidate the mechanism of hyper-IFN-alpha production using New Zealand Black mice
Fri Oct 15 00:00:00 UTC 2004
Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice.
Journal of immunology (Baltimore, Md. : 1950)
Zheng SJ,Jiang J,Shen H,Chen YH
MA1-70098 was used in flow cytometry to identify a role for TRAIL in apoptosis during listeriosis
Mon Nov 01 00:00:00 UTC 2004
The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis.
International immunology
Ishihara K,Sawa S,Ikushima H,Hirota S,Atsumi T,Kamimura D,Park SJ,Murakami M,Kitamura Y,Iwakura Y,Hirano T
MA1-70098 was used in flow cytometry to characterize a new mouse model of rheumatoid arthritis.
Mon Mar 01 00:00:00 UTC 2004
Increased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domains.
Molecular and cellular biology
Iseki M,Kubo C,Kwon SM,Yamaguchi A,Kataoka Y,Yoshida N,Takatsu K,Takaki S
MA1-70098 was used in flow cytometry to characterize adaptor molecule containing PH and SH2 domains knock out mice
Mon Mar 01 00:00:00 UTC 2004
Pivotal role of granulocyte colony-stimulating factor in the development of progenitors in the common myeloid pathway.
Blood
Richards MK,Liu F,Iwasaki H,Akashi K,Link DC
MA1-70098 was used in flow cytometry to investigate the role of granulocyte colony-stimulating factor on hematopoietic progenitors in vivo.
Sat Nov 15 00:00:00 UTC 2003
TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice.
The Journal of allergy and clinical immunology
Kusunoki T,Sugai M,Katakai T,Omatsu Y,Iyoda T,Inaba K,Nakahata T,Shimizu A,Yokota Y
MA1-70098 was used in flow cytometry to discuss mechanisms that regulate the TH1/TH2 balance.
Wed Jan 01 00:00:00 UTC 2003
Common expression of an unusual CD45 isoform on T cells from patients with large granular lymphocyte leukaemia and autoimmune lymphoproliferative syndrome.
British journal of haematology
Bleesing JJ,Janik JE,Fleisher TA
MA1-70098 was used in flow cytometry to examine CD45 expression on T-cells from large granular lymphocyte leukemia and autoimmune lymphoproliferative syndrome.
Wed Jan 01 00:00:00 UTC 2003
Extensive proliferation of T cell lineage-restricted progenitors in the thymus: an essential process for clonal expression of diverse T cell receptor beta chains.
European journal of immunology
Kawamoto H,Ohmura K,Fujimoto S,Lu M,Ikawa T,Katsura Y
MA1-70098 was used in flow cytometry to assess the proliferative potential of thymic progenitors that are T cell lineage restricted.
Sat Mar 01 00:00:00 UTC 2003
Passive transfer of flt-3L-derived dendritic cells delays diabetes development in NOD mice and associates with early production of interleukin (IL)-4 and IL-10 in the spleen of recipient mice.
Clinical and experimental immunology
Morin J,Faideau B,Gagnerault MC,Lepault F,Boitard C,Boudaly S
MA1-70098 was used in flow cytometry to assess the contribution of DC function in non-obese diabetic mice.
Mon Dec 01 00:00:00 UTC 2003
Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Otten LA,Tacchini-Cottier F,Lohoff M,Annunziato F,Cosmi L,Scarpellino L,Louis J,Steimle V,Reith W,Acha-Orbea H
MA1-70098 was used in flow cytometry to investigate the role of MHC class II transactivator in T cell differentiation.
Sat Feb 01 00:00:00 UTC 2003
Differential c-Myc responsiveness to B cell receptor ligation in B cell-negative selection.
Journal of immunology (Baltimore, Md. : 1950)
Leider N,Melamed D
MA1-70098 was used in flow cytometry to test if differential c-Myc responsiveness to B cell receptor ligation is associated with the mechanism of negative selection in immature B cells.
Mon Sep 01 00:00:00 UTC 2003
A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection.
The Journal of general virology
Reading PC,Smith GL
MA1-70098 was used in flow cytometry to study the early inflammatory response of mice infected with vaccinia virus strain Western Reserve.
Fri Aug 01 00:00:00 UTC 2003
Immunoglobulin and cytokine production from spleen lymphocytes is modulated in C57BL/6J mice by dietary cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid.
The Journal of nutrition
Yamasaki M,Chujo H,Hirao A,Koyanagi N,Okamoto T,Tojo N,Oishi A,Iwata T,Yamauchi-Sato Y,Yamamoto T,Tsutsumi K,Tachibana H,Yamada K
MA1-70098 was used in flow cytometry to study the effect of dietary cis-9, trans- and trans-0, cis-2 conjugated linoleic acid on immunoglobulin and cytokine production from spleen lymphocytes in C57BL/6J mice.
Sat Mar 01 00:00:00 UTC 2003
Granulocyte-dendritic cell unbalance in the non-obese diabetic mice.
Cellular immunology
Morin J,Chimènes A,Boitard C,Berthier R,Boudaly S
MA1-70098 was used in flow cytometry to investigate DCs in non-obese diabetic mice.
Thu May 01 00:00:00 UTC 2003
Development of thymic microenvironments in vitro is oxygen-dependent and requires permanent presence of T-cell progenitors.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Germeraad WT,Kawamoto H,Itoi M,Jiang Y,Amagai T,Katsura Y,van Ewijk W
MA1-70098 was used in flow cytometry to investigate factors that mediate induction and maintenance of the 3D configuration of the epithelial network in fetal thymic lobes in vitro.
Mon Sep 01 00:00:00 UTC 2003
Human B cells express a CD45 isoform that is similar to murine B220 and is downregulated with acquisition of the memory B-cell marker CD27.
Cytometry. Part B, Clinical cytometry
Bleesing JJ,Fleisher TA
MA1-70098 was used in flow cytometry to characterize B220 expression on human B cells.
Wed Jan 01 00:00:00 UTC 2003
A comparison of murine T-cell-depleted adult bone marrow and full-term fetal blood cells in hematopoietic engraftment and immune reconstitution.
Blood
Chen BJ,Cui X,Sempowski GD,Gooding ME,Liu C,Haynes BF,Chao NJ
MA1-70098 was used in flow cytometry to compare myeloid and lymphoid recovery using bone marrow and cord blood as sources of stem cells.
Tue Jan 01 00:00:00 UTC 2002
Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficit.
Journal of immunology (Baltimore, Md. : 1950)
Cabatingan MS,Schmidt MR,Sen R,Woodland RT
MA1-70098 was used in flow cytometry to investigate homeostatic B cell proliferation.
Sun Dec 15 00:00:00 UTC 2002
Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo.
International immunology
Prasad SJ,Goodnow CC
MA1-70098 was used in flow cytometry to characterize the differences in dendritic cell generation in vivo caused by non-MHC NOD genes.
Sat Jun 01 00:00:00 UTC 2002
In vitro and in vivo regulation by macrophage migration inhibitory factor (MIF) of expression of MHC-II, costimulatory, adhesion, receptor, and cytokine molecules.
Cellular immunology
Stavitsky AB,Xianli J
MA1-70098 was used in flow cytometry to investigate how migration inhibitory factor regulates immune responses.
Tue Dec 24 00:00:00 UTC 2002
NK1.1+ cell depletion in vivo fails to prevent protection against infection with the murine nematode parasite Trichuris muris.
Parasite immunology
Koyama K
MA1-70098 was used in flow cytometry to test if NKT cells produce IL-4 in response to T. muris infection and induce an Th2 response.
Tue Jun 03 00:00:00 UTC 2003
Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen.
The Journal of experimental medicine
Schneider P,Takatsuka H,Wilson A,Mackay F,Tardivel A,Lens S,Cachero TG,Finke D,Beermann F,Tschopp J
MA1-70098 was used in immunohistochemistry (frozen) to elucidate the roles of BAFF and APRIL in B cell development.
Mon Dec 03 00:00:00 UTC 2001
Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency.
European journal of immunology
Attinger A,MacDonald HR,Acha-Orbea H
MA1-70098 was used in immunocytochemistry to report that the lymphoid environment limits T cell proliferation in response to high superantigen levels.
Thu Mar 01 00:00:00 UTC 2001
Transgenic expression of CD95 ligand on thyroid follicular cells confers immune privilege upon thyroid allografts.
Journal of immunology (Baltimore, Md. : 1950)
Tourneur L,Malassagne B,Batteux F,Fabre M,Mistou S,Lallemand E,Lores P,Chiocchia G
MA1-70098 was used in flow cytometry to report that ectopic FasL expression prevents thyroid allograft rejection.
Wed Aug 01 00:00:00 UTC 2001
Extrafollicular plasmablast B cells play a key role in carrying retroviral infection to peripheral organs.
Journal of immunology (Baltimore, Md. : 1950)
Finke D,Baribaud F,Diggelmann H,Acha-Orbea H
MA1-70098 was used in flow cytometry to explore the migration properties of B cells after differentiation in murine peripheral lymph node infected with mouse mammary tumor virus.
Tue May 15 00:00:00 UTC 2001
Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independent deletion of superantigen-reactive peripheral T cells.
International immunology
Izeradjene K,Revillard JP,Genestier L
MA1-70098 was used in flow cytometry to assess the effects of folate analogues on superantigen-reactive peripheral T cells in vivo.
Mon Jan 01 00:00:00 UTC 2001
Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity.
International immunology
Shimizu C,Kawamoto H,Yamashita M,Kimura M,Kondou E,Kaneko Y,Okada S,Tokuhisa T,Yokoyama M,Taniguchi M,Katsura Y,Nakayama T
MA1-70098 was used in flow cytometry to study regulation of the lck in T cell lineage commitment.
Mon Jan 01 00:00:00 UTC 2001
Endogenous inhibition of antimycobacterial immunity by IL-10 varies between mycobacterial species.
Scandinavian journal of immunology
Roach DR,Martin E,Bean AG,Rennick DM,Briscoe H,Britton WJ
MA1-70098 was used in flow cytometry to elucidate the role of IL-10 in mycobacterial infections.
Thu Aug 09 00:00:00 UTC 2001
Uptake and presentation of antigen to T cells by primary colonic epithelial cells in normal and diseased states.
Gastroenterology
Telega GW,Baumgart DC,Carding SR
MA1-70098 was used in flow cytometry to determine the immunoregulatory properties of primary colonic epithelial cells.
Fri Dec 01 00:00:00 UTC 2000
Murine pro-B cells require IL-7 and its receptor complex to up-regulate IL-7R alpha, terminal deoxynucleotidyltransferase, and c mu expression.
Journal of immunology (Baltimore, Md. : 1950)
Wei C,Zeff R,Goldschneider I
MA1-70098 was used in flow cytometry to elucidate the role of IL-7 in B cell development.
Tue Feb 15 00:00:00 UTC 2000
Dendritic cells in the induction of protective and nonprotective anticryptococcal cell-mediated immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Bauman SK,Nichols KL,Murphy JW
MA1-70098 was used in flow cytometry to examine the contribution of different DC subsets during infection with Cryptococcus neoformans.
Sat Jul 01 00:00:00 UTC 2000
Preservation of graft-versus-infection effects after suicide gene therapy for prevention of graft-versus-host disease.
Human gene therapy
Cohen JL,Saron MF,Boyer O,Thomas-Vaslin V,Bellier B,Lejeune L,Charlotte F,Klatzmann D
MA1-70098 was used in flow cytometry to assess the recovery of functional antiviral immune responses in ganciclovir-treated mice that express viral thymidine kinase
Sun Dec 10 00:00:00 UTC 2000
Latent herpes simplex virus-1 infection in SCID mice transferred with immune CD4+T cells: a new model for latency.
Archives of virology
Minagawa H,Yanagi Y
MA1-70098 was used in blocking or activating experiment to investigate the role of CD4+T cells in the survival of SCID mice with latent herpes simplex virus-1 infection
Thu Feb 22 00:00:00 UTC 2001
Preferential binding of mouse mammary tumor virus to B lymphocytes.
Journal of virology
Baribaud F,Shaw AV,Scarpellino L,Diggelmann H,Acha-Orbea H
MA1-70098 was used in flow cytometry to determine the distribution of the viral receptors on fresh mouse lymphocytes.
Wed Sep 01 00:00:00 UTC 1999
Emergence of T cell progenitors without B cell or myeloid differentiation potential at the earliest stage of hematopoiesis in the murine fetal liver.
Journal of immunology (Baltimore, Md. : 1950)
Kawamoto H,Ohmura K,Fujimoto S,Katsura Y
MA1-70098 was used in flow cytometry to assess if progenitors colonizing the thymus are T cell lineage restricted.
Mon Mar 01 00:00:00 UTC 1999
Gene therapy of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for Fas ligand.
Journal of immunology (Baltimore, Md. : 1950)
Batteux F,Tourneur L,Trebeden H,Charreire J,Chiocchia G
MA1-70098 was used in flow cytometry to study FasL expression on thyrocytes.
Fri Jan 01 00:00:00 UTC 1999
Persistence of autoreactive T cell drive is required to elicit anti-chromatin antibodies in a murine model of drug-induced lupus.
Journal of immunology (Baltimore, Md. : 1950)
Kretz-Rommel A,Rubin RL
MA1-70098 was used in flow cytometry to study antibody production in a mouse model of drug-induced lupus.
Fri Jan 15 00:00:00 UTC 1999
Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene.
Molecular and cellular biology
Pan L,Sato S,Frederick JP,Sun XH,Zhuang Y
MA1-70098 was used in flow cytometry to investigate the role of Id3 in tissue and embryo development.
Wed Sep 01 00:00:00 UTC 1999
Differential recruitment of T- and IgA B-lymphocytes in the developing mammary gland in relation to homing receptors and vascular addressins.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Tanneau GM,Hibrand-Saint Oyant L,Chevaleyre CC,Salmon HP
MA1-70098 was used in flow cytometry to study T and B cell colonization of the mammary gland.
Wed Dec 01 00:00:00 UTC 1999
Generation of B lymphoma cell lines from knockout mice by transformation in vivo with an Emu-myc transgene.
Journal of immunological methods
Corcoran LM,Tawfilis S,Barlow LJ
MA1-70098 was used in flow cytometry to describe a protocol for the efficient derivation of mutant B lymphoma cell lines.
Tue Aug 31 00:00:00 UTC 1999
Suppression of hematopoietic activity in tenascin-C-deficient mice.
Blood
Ohta M,Sakai T,Saga Y,Aizawa S,Saito M
MA1-70098 was used in flow cytometry to determine if Tenascin-C plays role in hematopoiesis.
Mon Jun 01 00:00:00 UTC 1998
Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice.
Journal of immunology (Baltimore, Md. : 1950)
Contractor NV,Bassiri H,Reya T,Park AY,Baumgart DC,Wasik MA,Emerson SG,Carding SR
MA1-70098 was used in flow cytometry to determine if the microbiota contributes to autoimmunity in IL-2 deficient mice.
Thu Jan 01 00:00:00 UTC 1998
A functional B cell receptor transgene allows efficient IL-7-independent maturation of B cell precursors.
Journal of immunology (Baltimore, Md. : 1950)
Melamed D,Kench JA,Grabstein K,Rolink A,Nemazee D
MA1-70098 was used in flow cytometry to elucidate the IL-7 inhibitory effects on B cell development and maturation.
Fri Aug 01 00:00:00 UTC 1997
oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function.
Journal of immunology (Baltimore, Md. : 1950)
Humbert PO,Corcoran LM
MA1-70098 was used in flow cytometry to report that Oct-2 is required for normal humoral responses upon immunization with T cell-dependent and -independent antigens.
Mon Dec 01 00:00:00 UTC 1997
Mechanism of concordant corneal xenograft rejection in mice: synergistic effects of anti-leukocyte function-associated antigen-1 monoclonal antibody and FK506.
Transplantation
Yamagami S,Isobe M,Yamagami H,Hori J,Tsuru T
MA1-70098 was used in immunocytochemistry to elucidate mechanisms of corneal xenogeneic immunoreaction.
Tue Jul 15 00:00:00 UTC 1997
Continued differentiation during B lymphopoiesis requires signals in addition to cell survival.
International immunology
Tarlinton DM,Corcoran LM,Strasser A
MA1-70098 was used in flow cytometry to study the contribution of Ig heavy chain-containing receptors on B cell development.
Wed Oct 01 00:00:00 UTC 1997
Contact hypersensitivity to disodium hexachloroplatinate in mice.
Toxicology letters
Schuppe HC,Kulig J,Lerchenmüller C,Becker D,Gleichmann E,Kind P
MA1-70098 was used in flow cytometry to characterize skin irritation and induction of contact hypersensitivity by halide platinum salts.
Mon Dec 01 00:00:00 UTC 1997
Interleukin-12 (IL-12) and IL-18 synergistically induce the fungicidal activity of murine peritoneal exudate cells against Cryptococcus neoformans through production of gamma interferon by natural killer cells.
Infection and immunity
Zhang T,Kawakami K,Qureshi MH,Okamura H,Kurimoto M,Saito A
MA1-70098 was used in flow cytometry to identify the IFN-gamma-producing peritoneal cells after stimulation with IL-12 and IL-18.
Mon Sep 01 00:00:00 UTC 1997
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.
The Journal of experimental medicine
Goodell MA,Brose K,Paradis G,Conner AS,Mulligan RC
MA1-70098 was used in immunoprecipitation to use Hoechst 33342 to characterize hematopoietic stem cells.
Mon Apr 01 00:00:00 UTC 1996
Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells.
The Journal of experimental medicine
Hattori N,Kawamoto H,Katsura Y
MA1-70098 was used in flow cytometry to report that FcR is a useful marker to isolate the most immature population of murine fetal thymic cells.
Fri Nov 01 00:00:00 UTC 1996
A vascular smooth muscle-specific CD4+ T cell line that induces pulmonary vasculitis in MRL-+/+ mice.
Clinical and experimental immunology
Sumita S,Ozaki S,Okazaki T,Sobajima J,Nakao K
MA1-70098 was used in flow cytometry to develop and characterize a MV1-induced vasculitis model.
Mon Jul 01 00:00:00 UTC 1996
Reduced development of CD4-8-B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules.
European journal of immunology
Ohteki T,Iwamoto M,Izui S,MacDonald HR
MA1-70098 was used in flow cytometry to examine the origin of double negative T cells using Ipr mice.
Sun Jan 01 00:00:00 UTC 1995
Lack of L-selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel-14 antibody treatment.
European journal of immunology
Lepault F,Gagnerault MC,Faveeuw C,Bazin H,Boitard C
MA1-70098 was used in flow cytometry to assess the role of L-selectin in the pathogenesis of autoimmune diabetes.
Thu Jun 01 00:00:00 UTC 1995
Conditional ablation of dendritic cells in transgenic mice.
Journal of immunology (Baltimore, Md. : 1950)
Salomon B,Lorès P,Pioche C,Racz P,Jami J,Klatzmann D
MA1-70098 was used in flow cytometry to generate and characterize a DC deficient mouse using HIV.
Sat Jan 15 00:00:00 UTC 1994
Biologic activities of the murine beta-chemokine TCA3.
Journal of immunology (Baltimore, Md. : 1950)
Luo Y,Laning J,Devi S,Mak J,Schall TJ,Dorf ME
MA1-70098 was used in flow cytometry to study the murine beta-chemokine TCA3 in vivo and in vitro.
Tue Nov 15 00:00:00 UTC 1994
A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells.
Molecular and cellular biology
Longmore GD,Pharr PN,Lodish HF
MA1-70098 was used in flow cytometry to identify the sites and effects of proviral integration in cells infected with spleen focus-forming virus.
Fri Apr 01 00:00:00 UTC 1994
Administration of anti-CD45 mAb specific for a B cell-restricted epitope abrogates the B cell response to a T-dependent antigen in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Domiati-Saad R,Ogle EW,Justement LB
MA1-70098 was used in blocking or activating experiment to determine the role of CD45 in B cell activation and differentiation in response to T-dependent antigen
Wed Dec 01 00:00:00 UTC 1993
CD10/NEP is expressed on Thy-1low B220+ murine B-cell progenitors and functions to regulate stromal cell-dependent lymphopoiesis.
Blood
Salles G,Chen CY,Reinherz EL,Shipp MA
MA1-70098 was used in flow cytometry to study the function of the common acute lymphoblastic leukemia antigen in early lymphoid development.
Thu Oct 15 00:00:00 UTC 1992
Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells.
The Journal of experimental medicine
Ishida H,Hastings R,Kearney J,Howard M
MA1-70098 was used in immunocytochemistry to investigate the effects of IL-10 on Ly-1 B cells.
Fri May 01 00:00:00 UTC 1992
Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen.
The Journal of experimental medicine
Brink R,Goodnow CC,Crosbie J,Adams E,Eris J,Mason DY,Hartley SB,Basten A
MA1-70098 was used in flow cytometry to determine the functional contributions of IgM and IgD receptors on cellular development and responses to specific antigen.
Thu Oct 01 00:00:00 UTC 1992
