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Immunogen sequence: DPDFQARLT RSNSKCQGQL EVYLKDGWHM VCSQSWGRSS KQWEDPSQAS KVCQRLNCGV PLSLGPFLVT YTPQSSIICY GQLGSFSNCS HSRNDMCHSL GLTCLEPQKT TPPTTRPPPT TTPEPTAPPR LQLVAQSGGQ HCAGVVEFYS GSLGGTISYE AQDKTQDLEN FLCNNLQCGS FLKHLPETEA GRAQDPGEPR EHQPLPIQWK IQNSSCTSLE HCFRKIKPQK SGRVLALLCS GFQPKVQSRL VGGSSICEGT VEVRQGAQWA ALCDSSSARS SLRWEEVCRE QQCGSVNSYR VLDAGDPTSR GLFCPHQKLS QCHELWERNS YCKKVFVTCQ DPNPAGLAAG (30-378 aa encoded by BC027901)
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD antigen CD5; CD5; CD5 antigen (p56 62); CD5 antigen (p56-62); CD5 antigen p56-62; fCD5; Ly-1; Ly12; LyA; Lymphocyte antigen 1; Lymphocyte antigen T1/Leu-1; Pan T cell; T-cell surface glycoprotein CD5
Gene Aliases: CD5; LEU1; Ly-1; Ly-12; Ly-A; Lyt-1; T1
UniProt ID: (Human) P06127, (Mouse) P13379
Entrez Gene ID: (Human) 921, (Mouse) 12507
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