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Search Thermo Fisher Scientific
Invitrogen
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Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human CD5 (Met1-Pro372) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Protein Aliases: CD antigen CD5; CD5; CD5 antigen (p56 62); CD5 antigen (p56-62); CD5 antigen p56-62; fCD5; Ly12; LyA; Lymphocyte antigen T1/Leu-1; Pan T cell; T-cell surface glycoprotein CD5
Gene Aliases: CD5; LEU1; T1
UniProt ID: (Human) P06127
Entrez Gene ID: (Human) 921
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