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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD68 Antibodies

          Proteintech

          CD68 Polyclonal Antibody

          82 References
          View all (176) CD68 antibodies

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          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite CD68 Polyclonal Antibody

          • Antibody Testing Data (6)
          CD68 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CD68 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          CD68 Antibody (25747-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded Human liver tissue slide using (Product # 25747-1-AP) CD68 antibody at dilution of 1:4,000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CD68 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CD68 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CD68 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          CD68 Antibody in Flow Cytometry (Flow)
          CD68 Antibody in Flow Cytometry (Flow)
          CD68 Antibody in Immunoprecipitation (IP)

          Product Details

          25747-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          View 11 publications 11 publications

          Immunohistochemistry (IHC)

          -
          View 35 publications 35 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:4,000
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:200
          -

          Immunocytochemistry (ICC/IF)

          -
          View 30 publications 30 publications

          Flow Cytometry (Flow)

          0.2 µg/1x10^6 cells
          View 2 publications 2 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -

          Miscellaneous PubMed (MISC)

          -
          View 2 publications 2 publications

          Not applicable (N/A)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human, Mouse, Pig

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CD68 Fusion Protein Ag22815 (29-319 aa encoded by BC015557)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.4 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: SATLLPSFT VTPTVTESTG TTSHRTTKSH KTTTHRTTTT GTTSHGPTTA THNPTTTSHG NVTVHPTSNS TATSQGPSTA THSPATTSHG NATVHPTSNS TATSPGFTSS AHPEPPPPSP SPSPTSKETI GDYTWTNGSQ PCVHLQAQIQ IRVMYTTQGG GEAWGISVLN PNKTKVQGSC EGAHPHLLLS FPYGHLSFGF MQDLQQKVVY LSYMAVEYNV SFPHAAQWTF SAQNASLRDL QAPLGQSFSC SNSSIILSPA VHLDLLSLRL QAAQLPHTGV FGQSFSCPSD RS (29-319 aa encoded by BC015557)

          Target Information

          CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CD68; CD68 antigen; Gp110; macrophage antigen CD68; Macrosialin; scavenger receptor class D, member 1

          View more View less

          Gene Aliases: CD68; GP110; LAMP4; SCARD1

          View more View less

          UniProt ID: (Human) P34810, (Mouse) P31996

          View more View less

          Entrez Gene ID: (Human) 968, (Mouse) 12514

          View more View less

          Process(es)
          cellular response to organic substance
          It has to be done as per old AB suggested Products section.
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