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Invitrogen
CD68 Monoclonal Antibody (ED1), FITC
FIGURE: 1 / 2
CD68 Antibody (MA5-28262) in Flow
Journal of inflammation research 2022 -
Figure 3 Changes in the proportion of immune cells in myocardial tissue were analysed via flow cytometry. ( A ) The proportion of CD45 + cells in each group was detected by flow cytometry. ( B ) The proportion of CD45 + CD11b + cells in each group was detected by flow cytometry. ( C ) The proportion of CD68 + CD86 + cells in each group was detected by flow cytometry. ( D ) Pulmonary hypertension and LPS cau... View More
Product Details
MA5-28262
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Published species
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
ED1
Immunogen
Rat spleen cells
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Purification
Protein A
Storage buffer
PBS with 1% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745225
Product Specific Information
Mouse anti rat CD68, clone ED1 recognizes the rat ED1 antigen, a heavily glycosylated protein of approximately 90 -110 KDa, also known as rat CD68 (Dijkstra et al. 1985).
Target Information
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
Bioinformatics
Protein Aliases: CD68 antigen; macrosialin
Entrez Gene ID: (Rat) 287435
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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