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CD8b Antibody (MA5-28441) in Flow
Flow cytometry of CD8b in red cell lysed porcine blood. Sample was incubated with CD8b monoclonal antibody (Product # MA5-28441) and gated on lymphocytes. Figures are arranged as follows: A) RPE conjugated mouse anti porcine CD45RA and FITC conjugated mouse IgG1 isotype control. B) RPE conjugated mouse anti porcine CD45RA and FITC conjugated mouse anti porcine CD8b.
Product Details
MA5-28441
Product Specifications
Species Reactivity
Pig
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
PPT23
Immunogen
Porcine thymus membrane lysate
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Lyophilized
Purification
Protein A
Storage buffer
PBS with 5% sucrose, 1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745403
Product Specific Information
This antibody recognizes a different epitope of on the CD8 beta chain to clone PPT22.
Reconstitute with 1 mL distilled water
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD8; CD8 antigen beta polypeptide; CD8a; CD8alpha; CD8beta; Leu-2; MAL; p32; T-cell surface glycoprotein CD8 beta chain
Entrez Gene ID: (Pig) 396636
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