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Bethyl Laboratories
CDC123/C10orf7 Polyclonal Antibody
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CDC123/C10orf7 Antibody (A304-943A) in WB
Detection of human and mouse CDC123 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CDC123 antibody (Product # A304-943A) (lot A304-943A-1) used for WB at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A304-943A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 275 to 325 of human Cell division cycle protein 123 homolog.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid. The BCKD complex consists of 3 catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase, and a homodimeric dihydrolipoamide dehydrogenase. E1 is a thiamine pyrophosphate (TPP)-dependent enzyme. The reaction is irreversible and constitutes the first committed step in BCAA oxidation. The BCKDHB gene encodes the beta subunit of E1. The complex also contains 2 regulatory enzymes, a kinase and a phosphorylase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell division cycle 123 homolog; Cell division cycle protein 123 homolog; HT-1080; Protein D123; PZ32; Translation initiation factor eIF2 assembly protein
Gene Aliases: AA959893; C10orf7; CDC123; D123; G431001I09Rik
UniProt ID: (Human) O75794, (Mouse) Q8CII2
Entrez Gene ID: (Human) 8872, (Mouse) 98828
cell cycle
cell division
formation of cytoplasmic translation initiation complex
regulation of translation
cell cycle arrest
regulation of mitotic cell cycle
positive regulation of cell proliferation
positive regulation of translational initiation
eukaryotic translation initiation factor 2 complex assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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