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          • Primary Antibodies ›
          • CDC14A Antibodies

          Proteintech

          CDC14A Polyclonal Antibody

          1 Reference
          View all (7) CDC14A antibodies

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          Cite CDC14A Polyclonal Antibody

          • Antibody Testing Data (4)
          CDC14A Antibody in Western Blot (WB)
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          CDC14A Antibody in Western Blot (WB)
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          FIGURE: 1 / 4

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          CDC14A Antibody (13660-1-AP) in WB

          Human brain tissue were subjected to SDS PAGE followed by western blot with 13660-1-AP (CDC14A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CDC14A Antibody in Western Blot (WB)
          CDC14A Antibody in Western Blot (WB)
          CDC14A Antibody in Western Blot (WB)
          CDC14A Antibody in Western Blot (WB)

          Product Details

          13660-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CDC14A Fusion Protein Ag4556 (1-191 aa encoded by BC038979)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MAAESGELI GACEFMKDRL YFATLRNRPK STVNTHYFSI DEELVYENFY ADFGPLNLAM VYRYCCKLNK KLKSYSLSRK KIVHYTCFDQ RKRANAAFLI GAYAVIYLKK TPEEAYRALL SGSNPPYLPF RDASFGNCTY NLTILDCLQG IRKGLQHGFF DFETFDVDEY EHYEVILFTP LKPTFLISKS IM (1-191 aa encoded by BC038979)

          Target Information

          The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CDC10 (cell division cycle 10, S. cerevisiae, homolog); CDC14 cell division cycle 14 homolog A; Dual specificity protein phosphatase CDC14A

          View more View less

          Gene Aliases: A830059A17Rik; Cdc14; CDC14A; CDC14a1; CDC14A2; DFNB105; hCDC14

          View more View less

          UniProt ID: (Human) Q9UNH5, (Mouse) Q6GQT0

          View more View less

          Entrez Gene ID: (Human) 8556, (Rat) 310806, (Mouse) 229776

          View more View less

          Function(s)
          phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein binding protein tyrosine/serine/threonine phosphatase activity molecular_function hydrolase activity phosphatase activity
          Process(es)
          biological_process peptidyl-tyrosine dephosphorylation protein dephosphorylation cell cycle dephosphorylation cell division regulation of exit from mitosis cell proliferation cilium assembly mitotic spindle midzone assembly mitotic cell cycle arrest
          It has to be done as per old AB suggested Products section.
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