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Invitrogen
CDC14B/CDC14C Polyclonal Antibody
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CDC14B/CDC14C Antibody (PA5-99828) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded CDC14B/CDC14C in human kidney tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with CDC14B/CDC14C polyclonal antibody (Product # PA5-99828) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-99828
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CDC14B(Accession O60729), corresponding to amino acid residues A14-R64.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818761
Product Specific Information
Antibody detects endogenous levels of total CDC14B/C.
Target Information
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC14 cell division cycle 14 homolog B; Dual specificity protein phosphatase CDC14B
Gene Aliases: 2810432N10Rik; A530086E13Rik; AA472821; CDC14B; Cdc14B1; Cdc14B2; CDC14B3; hCDC14B
UniProt ID: (Human) O60729, (Mouse) Q6PFY9
Entrez Gene ID: (Human) 8555, (Mouse) 218294
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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