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CDC25C Antibody (H00000995-D01P) in WB
Western Blot analysis of CDC25C expression in transfected 293T cell line (H00000995-T01) by CDC25C MaxPab polyclonal antibody.
Lane 1: CDC25C transfected lysate(53.30 KDa).
Lane 2: Non-transfected lysate.
Lane 1: CDC25C transfected lysate(53.30 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00000995-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CDC25C (AAH19089.1, 1 a.a. approximately 473 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MSTELFSSTR EEGSSGSGPS FRSNQRKMLN LLLERDTSFT VCPDVPRTPV GKFLGDSANL SILSGGTPKC CLDLSNLSSG EITATQLTTS ADLDETGHLD SSGLQEVHLA GMNHDQHLMK CSPAQLLCST PNGLDRGHRK RDAMCSSSAN KENDNGNLVD SEMKYLGSPI TTVPKLDKNP NLGEDQAEEI SDELMEFSLK DQEAKVSRSG LYRSPSMPEN LNRPRLKQVE KFKDNTIPDK VKKKYFSGQG KLRKGLCLKK TVSLCDITIT QMLEEDSNQG HLIGDFSKVC ALPTVSGKHQ DLKYVNPETV AALLSGKFQG LIEKFYVIDC RYPYEYLGGH IQGALNLYSQ EELFNFFLKK PIVPLDTQKR IIIVFHCEFS SERGPRMCRC LREEDRSLNQ YPALYYPELY ILKGGYRDFF PEYMELCEPQ SYCPMHHQDH KTELLRCRSQ SKVQEGERQL REQIALLVKD MSP
Target Information
M-phase inducer phosphatase 3is an enzyme that in humans is encoded by theCDC25Cgene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dual specificity phosphatase Cdc25C; EC 3.1.3.48; M-phase inducer phosphatase 3; mitosis inducer CDC25; MPIP3; OTTHUMP00000159490; OTTHUMP00000224012; OTTHUMP00000224013; OTTHUMP00000224016; phosphotyrosine phosphatase; protein phosphatase 1, regulatory subunit 60
Gene Aliases: CDC25; CDC25C; PPP1R60
UniProt ID: (Human) Q9H2E8
Entrez Gene ID: (Human) 995
regulation of cyclin-dependent protein serine/threonine kinase activity
G2/M transition of mitotic cell cycle
DNA replication
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic nuclear division
regulation of mitotic nuclear division
spermatogenesis
cell proliferation
viral process
peptidyl-tyrosine dephosphorylation
cell division
regulation of cell cycle
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