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Invitrogen
CDK1-A Monoclonal Antibody (3E1.1)
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Product Details
MA1-91598
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Xenopus
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3E1.1
Immunogen
C terminal fragment, starting from methionine 85 of Xenopus Cdc2 .
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Purification
IgG fraction
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1955501
Product Specific Information
MA1-91598 detects CDC2 from Xenopus laevis samples.
Target Information
CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ABL1; CDK1-A; Cell division control protein 2 homolog 1; Cell division control protein 2-A; cell division cycle 2 like; Cell division protein kinase 1-A; Cyclin-dependent kinase 1-A; DKFZp686L20222; KCIP-1; maturation-promoting factor; MGC111195; MGC53829; OTTHUMP00000019660; P34 CDK1; P34 MGC111195; p34 protein kinase 1; Protein 1054
Gene Aliases: cdc-2; cdc2; cdc2-a; cdc28a; cdc2x1.1; cdk1-a; cdk1-b; MPF; p34cdc2; PSTAIR; xcdc2; XELAEV_18036802mg
UniProt ID: (Xenopus) P35567
Entrez Gene ID: (Xenopus) 380246
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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