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Product Details
H00008941-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CDK5R2 (AAH41771.1, 1 a.a. approximately 367 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGTVLSLSPA SSAKGRRPGG LPEEKKKAPP AGDEALGGYG APPVGKGGKG ESRLKRPSVL ISALTWRRLV AASAKKKKGS KKVTPKPAST GPDPLVQQRN RENLLRKGRD PPDGGGTAKP LAVPVPTVPA AAATCEPPSG GSAAAQPPGS GGGKPPPPPP PAPQVAPPVP GGSPRRVIVQ ASTGELLRCL GDFVCRRCYR LKELSPGELV GWFRGVDRSL LLQGWQDQAF ITPANLVFVY LLCRESLRGD ELASAAELQA AFLTCLYLAY SYMGNEISYP LKPFLVEPDK ERFWQRCLRL IQRLSPQMLR LNADPHFFTQ VFQDLKNEGE AAASGGGPPS GGAPAASSAA RDSCAAGTKH WTMNLDR
Target Information
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDK5 activator 2; Cyclin-dependent kinase 5 activator 2; cyclin-dependent kinase 5 activator isoform p39i; Cyclin-dependent kinase 5 regulatory subunit 2; cyclin-dependent kinase 5, regulatory subunit 2 (p39); neuronal CDK5 activator isoform; p39; p39I
Gene Aliases: CDK5R2; NCK5AI; P39; p39nck5ai
UniProt ID: (Human) Q13319
Entrez Gene ID: (Human) 8941
regulation of cyclin-dependent protein serine/threonine kinase activity
neuron migration
cerebellum development
superior olivary nucleus maturation
hippocampus development
layer formation in cerebral cortex
positive regulation of calcium ion-dependent exocytosis
positive regulation of protein serine/threonine kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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