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Invitrogen
CDX2 Recombinant Rabbit Monoclonal Antibody (9E0K5)
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FIGURE: 1 / 10
CDX2 Antibody (MA5-35215) in ICC/IF
Immunofluorescence analysis of CDX2 was performed using 70% confluent log phase LoVo cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with CDX2 Recombinant Rabbit Monoclonal Antibody (ARC0450) (Product # MA5-35215) at 5 µg/mL in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus... View More
Product Details
MA5-35215
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
9E0K5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDX2 (Q99626)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849119
Product Specific Information
Immunogen sequence: MYVSYLLDKD VSMYPSSVRH SGGLNLAPQN FVSPPQYPDY GGYHVAAAAA AAANLDSAQS PGPSWPAAYG APLREDWNGY APGGAAAAAN AVAHGLNGGS
Target Information
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; HGNC:1806; Homeobox protein CDX-2; homeobox protein miniCDX2
Gene Aliases: Cdx-2; CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626, (Mouse) P43241
Entrez Gene ID: (Human) 1045, (Mouse) 12591, (Rat) 66019
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
DNA binding
double-stranded DNA binding
protein binding
sequence-specific DNA binding
negative regulation of transcription from RNA polymerase II promoter
blood vessel development
blastocyst development
trophectodermal cell differentiation
placenta development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
pattern specification process
positive regulation of cell proliferation
endosome to lysosome transport
anterior/posterior pattern specification
cell differentiation
somatic stem cell population maintenance
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of cell differentiation
positive regulation of transcription, DNA-templated
labyrinthine layer development
organ morphogenesis
anterior/posterior axis specification
regulation of somitogenesis
intestinal epithelial cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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