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Immunogen sequence: LVIGKDHESK NSQLFAASQK FRKNTAPSLS SRKNMDLAKS GIKILVPKSP VKSRTAVDGF QSESPEKLDP VEQGQEDTVA PEVAAEKPVG ALLGPGAERA RMGSRPRI
Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDY-like; CDY-like, autosomal; Chromodomain Y-like protein; Crotonyl-CoA hydratase; DKFZp586C1622; MGC131936; testis-specific chromodomain Y-like protein
Gene Aliases: CDYL; CDYL1
UniProt ID: (Human) Q9Y232
Entrez Gene ID: (Human) 9425
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