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Product Details
25612-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CEBPZ Fusion Protein Ag11003 (705-1054 aa encoded by BC034475)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FCGAENTSL WELKKLSVHF HPSVALFAKT ILQGNYIQYS GDPLQDFTLM RFLDRFVYRN PKPHKGKENT DSVVMQPKRK HFIKDIRHLP VNSKEFLAKE ESQIPVDEVF FHRYYKKVAV KEKQKRDADE ESIEDVDDEE FEELIDTFED DNCFSSGKDD MDFAGNVKKR TKGAKDNTLD EDSEGSDDEL GNLDDDEVSL GSMDDEEFAE VDEDGGTFMD VLDDESESVP ELEVHSKVST KKSKRKGTDD FDFAGSFQGP RKKKRNLNDS SLFVSAEEFG HLLDENMGSK FDNIGMNAMA NKDNASLKQL RWEAERDDWL HNRDAKSIIK KKKHFKKKRI KTTQKTKKQR K (705-1054 aa encoded by BC034475)
Target Information
This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurrence of acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C EBP; C/EBP zeta; CBF; CCAAT-binding factor; CCAAT-box-binding transcription factor; CCAAT/enhancer binding protein (C/EBP), zeta; CCAAT/enhancer binding protein alpha (C/EBP) related sequence 1; CCAAT/enhancer binding protein cebp family zeta; CCAAT/enhancer-binding protein zeta; CEBP zeta; CTF2; HSPCBF
Gene Aliases: AI848081; CBF; CBF2; Cebpa-rs1; CEBPZ; HSP-CBF; NOC1
UniProt ID: (Human) Q03701, (Mouse) P53569
Entrez Gene ID: (Human) 10153, (Mouse) 12607
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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