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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chymotrypsin-like elastase family member 2A; Elastase 2, pancreatic; elastase 2A; Elastase-2; Elastase-2A; neutrophilic elastase
Gene Aliases: Cela2a; Ela-2; Ela2; Ela2a; ELAII; Elaii1
UniProt ID: (Mouse) P05208, (Rat) P00774
Entrez Gene ID: (Mouse) 13706, (Rat) 24332
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