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Invitrogen
CELSR2 Polyclonal Antibody
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Product Details
PA5-33423
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from C-terminus of human CELSR2 / EGFL2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550803
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Elephant, Panda, Horse, Rabbit (100%) Opossum (94%).
Target Information
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adhesion G protein-coupled receptor C2; cadherin EGF LAG seven-pas G-type receptor 2; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); EGF-like protein 2; EGF-like-domain, multiple 2; epidermal growth factor-like 2; Epidermal growth factor-like protein 2; Flamingo homolog; Flamingo homolog 3; flamingo-like protein celsr2; Flamingo1; FLJ34118; FLJ42737; FLJ45143; FLJ45845; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; Multiple epidermal growth factor-like domains protein 3; seven-pass transmembrane cadherin
Gene Aliases: ADGRC2; BOS_3201; CDHF10; CELSR2; EGFL2; flamingo; Flamingo1; I79_019398; KIAA0279; MEGF3; mfmi1; mKIAA0279
UniProt ID: (Human) Q9HCU4, (Mouse) Q9R0M0
Entrez Gene ID: (Human) 1952, (Bovine) 538194, (Dog) 479916, (Chinese hamster) 100751011, (Mouse) 53883, (Rat) 83465
neuron migration
cilium movement
regulation of transcription, DNA-templated
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
multicellular organism development
Wnt signaling pathway
ventricular system development
neural plate anterior/posterior regionalization
regulation of cell-cell adhesion
regulation of protein localization
cerebrospinal fluid secretion
cilium assembly
dendrite morphogenesis
spermatogenesis
Wnt signaling pathway, planar cell polarity pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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