Proteintech

CENPJ Polyclonal Antibody

CENPJ Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 5

CENPJ Antibody (11517-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using 11517-1-AP (CENPJ antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

Product Image Gallery

Product Details

11517-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 19 publications 19 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:10-1:100

View 38 publications 38 publications

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat, Zebrafish

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CENPJ Fusion Protein Ag2078 (1033-1338 aa encoded by BC024209)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.45 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: RENTDLREE IKVMERFRLD AWKRAEAIES SLEVEKKDKL ANTSVRFQNS QISSGTQVEK YKKNYLPMQG NPPRRSKSAP PRDLGNLDKG QAASPREPLE PLNFPDPEYK EEEEDQDIQG EISHPDGKVE KVYKNGCRVI LFPNGTRKEV SADGKTITVT FFNGDVKQVM PDQRVIYYYA AAQTTHTTYP EGLEVLHFSS GQIEKHYPDG RKEITFPDQT VKNLFPDGQE ESIFPDGTIV RVQRDGNKLI EFNNGQRELH TAQFKRREYP DGTVKTVYAN GHQETKYRSG RIRVKDKEGN VLMDTEL (1033-1338 aa encoded by BC024209)

Target Information

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Microcephaly gene Cenpj regulates axonal growth in cortical neurons through microtubule destabilization.

Journal of neurochemistry

Meneses Iack P,Rayêe D,Lent R,Ribeiro-Resende VT,Garcez PP

Sun May 01 00:00:00 UTC 2022

KIF24 depletion induces clustering of supernumerary centrosomes in PDAC cells.

Life science alliance

Mashima Y,Nohira H,Sugihara H,Dynlacht BD,Kobayashi T,Itoh H

Tue Nov 01 00:00:00 UTC 2022

Cartwheel disassembly regulated by CDK1-cyclin B kinase allows human centriole disengagement and licensing.

The Journal of biological chemistry

Huang F,Xu X,Xin G,Zhang B,Jiang Q,Zhang C

Thu Dec 01 00:00:00 UTC 2022

Centromere protein J is overexpressed in human glioblastoma and promotes cell proliferation and migration.

Journal of neurochemistry

de Freitas GPA,Geraldo LHM,Faria BM,Alves-Leon SV,de Souza JM,Moura-Neto V,Pontes B,Romão LF,Garcez PP

Thu Sep 01 00:00:00 UTC 2022

Centromere protein J is overexpressed in human glioblastoma and promotes cell proliferation and migration.

Journal of neurochemistry

de Freitas GPA,Geraldo LHM,Faria BM,Alves-Leon SV,de Souza JM,Moura-Neto V,Pontes B,Romão LF,Garcez PP

Thu Sep 01 00:00:00 UTC 2022

ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis.

EMBO reports

Song T,Yang Y,Zhou P,Ran J,Zhang L,Wu X,Xie W,Zhong T,Liu H,Liu M,Li D,Zhao H,Zhou J

Wed May 04 00:00:00 UTC 2022

The mechanism of acentrosomal spindle assembly in human oocytes.

Science (New York, N.Y.)

Wu T,Dong J,Fu J,Kuang Y,Chen B,Gu H,Luo Y,Gu R,Zhang M,Li W,Dong X,Sun X,Sang Q,Wang L

Fri Nov 18 00:00:00 UTC 2022

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.

Oncotarget

Gudi RR,Janakiraman H,Howe PH,Palanisamy V,Vasu C

Tue Apr 13 00:00:00 UTC 2021

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.

Oncotarget

Gudi RR,Janakiraman H,Howe PH,Palanisamy V,Vasu C

Tue Apr 13 00:00:00 UTC 2021

Modifier Genes in Microcephaly: A Report on WDR62, CEP63, RAD50 and PCNT Variants Exacerbating Disease Caused by Biallelic Mutations of ASPM and CENPJ.

Genes

Makhdoom EUH,Waseem SS,Iqbal M,Abdullah U,Hussain G,Asif M,Budde B,Höhne W,Tinschert S,Saadi SM,Yousaf H,Ali Z,Fatima A,Kaygusuz E,Khan A,Jameel M,Khan S,Tariq M,Anjum I,Altmüller J,Thiele H,Höning S,Baig SM,Nürnberg P,Hussain MS

Thu May 13 00:00:00 UTC 2021

Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly.

The Journal of cell biology

Chinen T,Yamazaki K,Hashimoto K,Fujii K,Watanabe K,Takeda Y,Yamamoto S,Nozaki Y,Tsuchiya Y,Takao D,Kitagawa D

Mon Feb 01 00:00:00 UTC 2021

Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR.

Scientific reports

Gudi R,Palanisamy V,Vasu C

Wed Jun 16 00:00:00 UTC 2021

The SON RNA splicing factor is required for intracellular trafficking structures that promote centriole assembly and ciliogenesis.

Molecular biology of the cell

Stemm-Wolf AJ,O'Toole ET,Sheridan RM,Morgan JT,Pearson CG

Fri Oct 01 00:00:00 UTC 2021

Sorting Nexin 27 Enables MTOC and Secretory Machinery Translocation to the Immune Synapse.

Frontiers in immunology

González-Mancha N,Rodríguez-Rodríguez C,Alcover A,Merida I

Mon Mar 07 00:00:00 UTC 2022

Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice.

Science China. Life sciences

Ding W,Zhang C,Wang B,Zhou X,Sun L,Zhong S,Liu J,Zhang J,Wang X,Wu Q

Mon Mar 01 00:00:00 UTC 2021

TRIM37 controls cancer-specific vulnerability to PLK4 inhibition.

Nature

Meitinger F,Ohta M,Lee KY,Watanabe S,Davis RL,Anzola JV,Kabeche R,Jenkins DA,Shiau AK,Desai A,Oegema K

Tue Sep 01 00:00:00 UTC 2020

The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development.

Human molecular genetics

Shohayeb B,Ho U,Yeap YY,Parton RG,Millard SS,Xu Z,Piper M,Ng DCH

Wed Jan 15 00:00:00 UTC 2020

The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development.

Human molecular genetics

Shohayeb B,Ho U,Yeap YY,Parton RG,Millard SS,Xu Z,Piper M,Ng DCH

Wed Jan 15 00:00:00 UTC 2020

Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ding W,Wu Q,Sun L,Pan NC,Wang X

Wed Mar 13 00:00:00 UTC 2019

Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ding W,Wu Q,Sun L,Pan NC,Wang X

Wed Mar 13 00:00:00 UTC 2019

Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ding W,Wu Q,Sun L,Pan NC,Wang X

Wed Mar 13 00:00:00 UTC 2019

Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ding W,Wu Q,Sun L,Pan NC,Wang X

Wed Mar 13 00:00:00 UTC 2019

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.

Nature communications

Holdgaard SG,Cianfanelli V,Pupo E,Lambrughi M,Lubas M,Nielsen JC,Eibes S,Maiani E,Harder LM,Wesch N,Foged MM,Maeda K,Nazio F,de la Ballina LR,Dötsch V,Brech A,Frankel LB,Jäättelä M,Locatelli F,Barisic M,Andersen JS,Bekker-Jensen S,Lund AH,Rogov VV,Papaleo E,Lanzetti L,De Zio D,Cecconi F

Fri Sep 13 00:00:00 UTC 2019

CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells.

Molecular biology of the cell

Ganapathi Sankaran D,Stemm-Wolf AJ,Pearson CG

Wed May 01 00:00:00 UTC 2019

Centrobin controls primary ciliogenesis in vertebrates.

The Journal of cell biology

Ogungbenro YA,Tena TC,Gaboriau D,Lalor P,Dockery P,Philipp M,Morrison CG

Mon Apr 02 00:00:00 UTC 2018

Centrobin controls primary ciliogenesis in vertebrates.

The Journal of cell biology

Ogungbenro YA,Tena TC,Gaboriau D,Lalor P,Dockery P,Philipp M,Morrison CG

Mon Apr 02 00:00:00 UTC 2018

Albatross/FBF1 contributes to both centriole duplication and centrosome separation.

Genes to cells : devoted to molecular & cellular mechanisms

Inoko A,Yano T,Miyamoto T,Matsuura S,Kiyono T,Goshima N,Inagaki M,Hayashi Y

Sat Dec 01 00:00:00 UTC 2018

Albatross/FBF1 contributes to both centriole duplication and centrosome separation.

Genes to cells : devoted to molecular & cellular mechanisms

Inoko A,Yano T,Miyamoto T,Matsuura S,Kiyono T,Goshima N,Inagaki M,Hayashi Y

Sat Dec 01 00:00:00 UTC 2018

PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN.

eLife

Sydor AM,Coyaud E,Rovelli C,Laurent E,Liu H,Raught B,Mennella V

Fri Aug 31 00:00:00 UTC 2018

PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN.

eLife

Sydor AM,Coyaud E,Rovelli C,Laurent E,Liu H,Raught B,Mennella V

Fri Aug 31 00:00:00 UTC 2018

NEK7 is required for G1 progression and procentriole formation.

Molecular biology of the cell

Gupta A,Tsuchiya Y,Ohta M,Shiratsuchi G,Kitagawa D

Sat Jul 15 00:00:00 UTC 2017

NEK7 is required for G1 progression and procentriole formation.

Molecular biology of the cell

Gupta A,Tsuchiya Y,Ohta M,Shiratsuchi G,Kitagawa D

Sat Jul 15 00:00:00 UTC 2017

NEK7 is required for G1 progression and procentriole formation.

Molecular biology of the cell

Gupta A,Tsuchiya Y,Ohta M,Shiratsuchi G,Kitagawa D

Sat Jul 15 00:00:00 UTC 2017

NEK7 is required for G1 progression and procentriole formation.

Molecular biology of the cell

Gupta A,Tsuchiya Y,Ohta M,Shiratsuchi G,Kitagawa D

Sat Jul 15 00:00:00 UTC 2017

Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.

Neuron

Jayaraman D,Kodani A,Gonzalez DM,Mancias JD,Mochida GH,Vagnoni C,Johnson J,Krogan N,Harper JW,Reiter JF,Yu TW,Bae BI,Walsh CA

Wed Nov 23 00:00:00 UTC 2016

Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.

Neuron

Jayaraman D,Kodani A,Gonzalez DM,Mancias JD,Mochida GH,Vagnoni C,Johnson J,Krogan N,Harper JW,Reiter JF,Yu TW,Bae BI,Walsh CA

Wed Nov 23 00:00:00 UTC 2016

Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.

Neuron

Jayaraman D,Kodani A,Gonzalez DM,Mancias JD,Mochida GH,Vagnoni C,Johnson J,Krogan N,Harper JW,Reiter JF,Yu TW,Bae BI,Walsh CA

Wed Nov 23 00:00:00 UTC 2016

Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.

Neuron

Jayaraman D,Kodani A,Gonzalez DM,Mancias JD,Mochida GH,Vagnoni C,Johnson J,Krogan N,Harper JW,Reiter JF,Yu TW,Bae BI,Walsh CA

Wed Nov 23 00:00:00 UTC 2016

53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration.

The Journal of cell biology

Meitinger F,Anzola JV,Kaulich M,Richardson A,Stender JD,Benner C,Glass CK,Dowdy SF,Desai A,Shiau AK,Oegema K

Mon Jul 18 00:00:00 UTC 2016

53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration.

The Journal of cell biology

Meitinger F,Anzola JV,Kaulich M,Richardson A,Stender JD,Benner C,Glass CK,Dowdy SF,Desai A,Shiau AK,Oegema K

Mon Jul 18 00:00:00 UTC 2016

Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole.

Nature communications

Tsuchiya Y,Yoshiba S,Gupta A,Watanabe K,Kitagawa D

Fri Aug 26 00:00:00 UTC 2016

Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole.

Nature communications

Tsuchiya Y,Yoshiba S,Gupta A,Watanabe K,Kitagawa D

Fri Aug 26 00:00:00 UTC 2016

Autophagy controls centrosome number by degrading Cep63.

Nature communications

Watanabe Y,Honda S,Konishi A,Arakawa S,Murohashi M,Yamaguchi H,Torii S,Tanabe M,Tanaka S,Warabi E,Shimizu S

Mon Nov 21 00:00:00 UTC 2016

Autophagy controls centrosome number by degrading Cep63.

Nature communications

Watanabe Y,Honda S,Konishi A,Arakawa S,Murohashi M,Yamaguchi H,Torii S,Tanabe M,Tanaka S,Warabi E,Shimizu S

Mon Nov 21 00:00:00 UTC 2016

Role for the IFT-A Complex in Selective Transport to the Primary Cilium.

Cell reports

Fu W,Wang L,Kim S,Li J,Dynlacht BD

Tue Nov 01 00:00:00 UTC 2016

Role for the IFT-A Complex in Selective Transport to the Primary Cilium.

Cell reports

Fu W,Wang L,Kim S,Li J,Dynlacht BD

Tue Nov 01 00:00:00 UTC 2016

Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis.

Cell reports

Kim M,O'Rourke BP,Soni RK,Jallepalli PV,Hendrickson RC,Tsou MB

Tue Aug 02 00:00:00 UTC 2016

Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis.

Cell reports

Kim M,O'Rourke BP,Soni RK,Jallepalli PV,Hendrickson RC,Tsou MB

Tue Aug 02 00:00:00 UTC 2016

Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation.

Biochimica et biophysica acta

Kim JH,Ki SM,Joung JG,Scott E,Heynen-Genel S,Aza-Blanc P,Kwon CH,Kim J,Gleeson JG,Lee JE

Wed Jun 01 00:00:00 UTC 2016

Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation.

Biochimica et biophysica acta

Kim JH,Ki SM,Joung JG,Scott E,Heynen-Genel S,Aza-Blanc P,Kwon CH,Kim J,Gleeson JG,Lee JE

Wed Jun 01 00:00:00 UTC 2016

Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.

Science (New York, N.Y.)

Wong YL,Anzola JV,Davis RL,Yoon M,Motamedi A,Kroll A,Seo CP,Hsia JE,Kim SK,Mitchell JW,Mitchell BJ,Desai A,Gahman TC,Shiau AK,Oegema K

Fri Jun 05 00:00:00 UTC 2015

Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4.

Science (New York, N.Y.)

Wong YL,Anzola JV,Davis RL,Yoon M,Motamedi A,Kroll A,Seo CP,Hsia JE,Kim SK,Mitchell JW,Mitchell BJ,Desai A,Gahman TC,Shiau AK,Oegema K

Fri Jun 05 00:00:00 UTC 2015

RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity.

The EMBO journal

Shiratsuchi G,Takaoka K,Ashikawa T,Hamada H,Kitagawa D

Fri Jan 02 00:00:00 UTC 2015

RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity.

The EMBO journal

Shiratsuchi G,Takaoka K,Ashikawa T,Hamada H,Kitagawa D

Fri Jan 02 00:00:00 UTC 2015

RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity.

The EMBO journal

Shiratsuchi G,Takaoka K,Ashikawa T,Hamada H,Kitagawa D

Fri Jan 02 00:00:00 UTC 2015

RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity.

The EMBO journal

Shiratsuchi G,Takaoka K,Ashikawa T,Hamada H,Kitagawa D

Fri Jan 02 00:00:00 UTC 2015

A Short CEP135 Splice Isoform Controls Centriole Duplication.

Current biology : CB

Dahl KD,Sankaran DG,Bayless BA,Pinter ME,Galati DF,Heasley LR,Giddings TH,Pearson CG

Mon Oct 05 00:00:00 UTC 2015

A Short CEP135 Splice Isoform Controls Centriole Duplication.

Current biology : CB

Dahl KD,Sankaran DG,Bayless BA,Pinter ME,Galati DF,Heasley LR,Giddings TH,Pearson CG

Mon Oct 05 00:00:00 UTC 2015

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication.

Molecular biology of the cell

Van de Mark D,Kong D,Loncarek J,Stearns T

Sun Nov 01 00:00:00 UTC 2015

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication.

Molecular biology of the cell

Van de Mark D,Kong D,Loncarek J,Stearns T

Sun Nov 01 00:00:00 UTC 2015

Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1.

Nature communications

Garcez PP,Diaz-Alonso J,Crespo-Enriquez I,Castro D,Bell D,Guillemot F

Tue Mar 10 00:00:00 UTC 2015

Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1.

Nature communications

Garcez PP,Diaz-Alonso J,Crespo-Enriquez I,Castro D,Bell D,Guillemot F

Tue Mar 10 00:00:00 UTC 2015

Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1.

Nature communications

Garcez PP,Diaz-Alonso J,Crespo-Enriquez I,Castro D,Bell D,Guillemot F

Tue Mar 10 00:00:00 UTC 2015

Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1.

Nature communications

Garcez PP,Diaz-Alonso J,Crespo-Enriquez I,Castro D,Bell D,Guillemot F

Tue Mar 10 00:00:00 UTC 2015

De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly.

eLife

Wang WJ,Acehan D,Kao CH,Jane WN,Uryu K,Tsou MF

Thu Nov 26 00:00:00 UTC 2015

De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly.

eLife

Wang WJ,Acehan D,Kao CH,Jane WN,Uryu K,Tsou MF

Thu Nov 26 00:00:00 UTC 2015

Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation.

Nature communications

Shukla A,Kong D,Sharma M,Magidson V,Loncarek J

Fri Aug 21 00:00:00 UTC 2015

Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation.

Nature communications

Shukla A,Kong D,Sharma M,Magidson V,Loncarek J

Fri Aug 21 00:00:00 UTC 2015

Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation.

Nature communications

Shukla A,Kong D,Sharma M,Magidson V,Loncarek J

Fri Aug 21 00:00:00 UTC 2015

Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation.

Nature communications

Shukla A,Kong D,Sharma M,Magidson V,Loncarek J

Fri Aug 21 00:00:00 UTC 2015

Centrobin-mediated regulation of the centrosomal protein 4.1-associated protein (CPAP) level limits centriole length during elongation stage.

The Journal of biological chemistry

Gudi R,Haycraft CJ,Bell PD,Li Z,Vasu C

Fri Mar 13 00:00:00 UTC 2015

SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplication.

Developmental cell

Fong CS,Kim M,Yang TT,Liao JC,Tsou MF

Mon Jul 28 00:00:00 UTC 2014

SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplication.

Developmental cell

Fong CS,Kim M,Yang TT,Liao JC,Tsou MF

Mon Jul 28 00:00:00 UTC 2014

PIPKIγ targets to the centrosome and restrains centriole duplication.

Journal of cell science

Xu Q,Zhang Y,Xiong X,Huang Y,Salisbury JL,Hu J,Ling K

Sat Mar 15 00:00:00 UTC 2014

PIPKIγ targets to the centrosome and restrains centriole duplication.

Journal of cell science

Xu Q,Zhang Y,Xiong X,Huang Y,Salisbury JL,Hu J,Ling K

Sat Mar 15 00:00:00 UTC 2014

PIPKIγ targets to the centrosome and restrains centriole duplication.

Journal of cell science

Xu Q,Zhang Y,Xiong X,Huang Y,Salisbury JL,Hu J,Ling K

Sat Mar 15 00:00:00 UTC 2014

PIPKIγ targets to the centrosome and restrains centriole duplication.

Journal of cell science

Xu Q,Zhang Y,Xiong X,Huang Y,Salisbury JL,Hu J,Ling K

Sat Mar 15 00:00:00 UTC 2014

Centrobin-centrosomal protein 4.1-associated protein (CPAP) interaction promotes CPAP localization to the centrioles during centriole duplication.

The Journal of biological chemistry

Gudi R,Zou C,Dhar J,Gao Q,Vasu C

Fri May 30 00:00:00 UTC 2014

Centrobin-centrosomal protein 4.1-associated protein (CPAP) interaction promotes CPAP localization to the centrioles during centriole duplication.

The Journal of biological chemistry

Gudi R,Zou C,Dhar J,Gao Q,Vasu C

Fri May 30 00:00:00 UTC 2014

Centrobin-centrosomal protein 4.1-associated protein (CPAP) interaction promotes CPAP localization to the centrioles during centriole duplication.

The Journal of biological chemistry

Gudi R,Zou C,Dhar J,Gao Q,Vasu C

Fri May 30 00:00:00 UTC 2014

Centrobin-centrosomal protein 4.1-associated protein (CPAP) interaction promotes CPAP localization to the centrioles during centriole duplication.

The Journal of biological chemistry

Gudi R,Zou C,Dhar J,Gao Q,Vasu C

Fri May 30 00:00:00 UTC 2014

Stabilization of cartwheel-less centrioles for duplication requires CEP295-mediated centriole-to-centrosome conversion.

Cell reports

Izquierdo D,Wang WJ,Uryu K,Tsou MF

Thu Aug 21 00:00:00 UTC 2014

Stabilization of cartwheel-less centrioles for duplication requires CEP295-mediated centriole-to-centrosome conversion.

Cell reports

Izquierdo D,Wang WJ,Uryu K,Tsou MF

Thu Aug 21 00:00:00 UTC 2014

The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis.

Nature cell biology

Zhao H,Zhu L,Zhu Y,Cao J,Li S,Huang Q,Xu T,Huang X,Yan X,Zhu X

Sun Dec 01 00:00:00 UTC 2013

The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis.

Nature cell biology

Zhao H,Zhu L,Zhu Y,Cao J,Li S,Huang Q,Xu T,Huang X,Yan X,Zhu X

Sun Dec 01 00:00:00 UTC 2013

The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis.

Nature cell biology

Zhao H,Zhu L,Zhu Y,Cao J,Li S,Huang Q,Xu T,Huang X,Yan X,Zhu X

Sun Dec 01 00:00:00 UTC 2013

The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis.

Nature cell biology

Zhao H,Zhu L,Zhu Y,Cao J,Li S,Huang Q,Xu T,Huang X,Yan X,Zhu X

Sun Dec 01 00:00:00 UTC 2013

A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

Cancer research

Lau T,Chan E,Callow M,Waaler J,Boggs J,Blake RA,Magnuson S,Sambrone A,Schutten M,Firestein R,Machon O,Korinek V,Choo E,Diaz D,Merchant M,Polakis P,Holsworth DD,Krauss S,Costa M

Wed May 15 00:00:00 UTC 2013

A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

Cancer research

Lau T,Chan E,Callow M,Waaler J,Boggs J,Blake RA,Magnuson S,Sambrone A,Schutten M,Firestein R,Machon O,Korinek V,Choo E,Diaz D,Merchant M,Polakis P,Holsworth DD,Krauss S,Costa M

Wed May 15 00:00:00 UTC 2013

CEP120 and SPICE1 cooperate with CPAP in centriole elongation.

Current biology : CB

Comartin D,Gupta GD,Fussner E,Coyaud É,Hasegan M,Archinti M,Cheung SW,Pinchev D,Lawo S,Raught B,Bazett-Jones DP,Lüders J,Pelletier L

Mon Jul 22 00:00:00 UTC 2013

CEP120 and SPICE1 cooperate with CPAP in centriole elongation.

Current biology : CB

Comartin D,Gupta GD,Fussner E,Coyaud É,Hasegan M,Archinti M,Cheung SW,Pinchev D,Lawo S,Raught B,Bazett-Jones DP,Lüders J,Pelletier L

Mon Jul 22 00:00:00 UTC 2013

CEP120 and SPICE1 cooperate with CPAP in centriole elongation.

Current biology : CB

Comartin D,Gupta GD,Fussner E,Coyaud É,Hasegan M,Archinti M,Cheung SW,Pinchev D,Lawo S,Raught B,Bazett-Jones DP,Lüders J,Pelletier L

Mon Jul 22 00:00:00 UTC 2013

CEP120 and SPICE1 cooperate with CPAP in centriole elongation.

Current biology : CB

Comartin D,Gupta GD,Fussner E,Coyaud É,Hasegan M,Archinti M,Cheung SW,Pinchev D,Lawo S,Raught B,Bazett-Jones DP,Lüders J,Pelletier L

Mon Jul 22 00:00:00 UTC 2013

Tankyrase 1 regulates centrosome function by controlling CPAP stability.

EMBO reports

Kim MK,Dudognon C,Smith S

Wed Aug 01 00:00:00 UTC 2012

Tankyrase 1 regulates centrosome function by controlling CPAP stability.

EMBO reports

Kim MK,Dudognon C,Smith S

Wed Aug 01 00:00:00 UTC 2012

Tankyrase 1 regulates centrosome function by controlling CPAP stability.

EMBO reports

Kim MK,Dudognon C,Smith S

Wed Aug 01 00:00:00 UTC 2012

Tankyrase 1 regulates centrosome function by controlling CPAP stability.

EMBO reports

Kim MK,Dudognon C,Smith S

Wed Aug 01 00:00:00 UTC 2012

Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture.

Molecular & cellular proteomics : MCP

Al-Hakim AK,Bashkurov M,Gingras AC,Durocher D,Pelletier L

Fri Jun 01 00:00:00 UTC 2012

Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture.

Molecular & cellular proteomics : MCP

Al-Hakim AK,Bashkurov M,Gingras AC,Durocher D,Pelletier L

Fri Jun 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: CENP-J; Centromere protein J; Centrosomal P4.1-associated protein; Centrosome assembly and centriole elongation protein; LAG-3-associated protein; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; microcephaly

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Gene Aliases: 4932437H03Rik; BM032; CENP-J; CENPJ; CPAP; Gm81; LAP; LIP1; MCPH6; Sas-4; Sas4; SASS4; SCKL4

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UniProt ID: (Human) Q9C067, (Mouse) Q569L8

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Entrez Gene ID: (Human) 55835, (Rat) 305909, (Mouse) 219103

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Function(s)

protein binding tubulin binding protein kinase binding protein domain specific binding transcription coactivator activity gamma-tubulin binding

Process(es)

G2/M transition of mitotic cell cycle DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest microtubule nucleation centriole replication regulation of centriole replication microtubule polymerization cell division centriole elongation astral microtubule nucleation positive regulation of JAK-STAT cascade regulation of nucleic acid-templated transcription

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CENPJ Polyclonal Antibody

CENPJ Antibody (11517-1-AP) in ICC/IF

Product Details

11517-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

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Bioinformatics

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