Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
CENPJ Antibody (H00055835-D01P) in WB
Western Blot analysis of CENPJ expression in transfected 293T cell line (H00055835-T01) by CENPJ MaxPab polyclonal antibody.
Lane 1: CENPJ transfected lysate(43.20 KDa).
Lane 2: Non-transfected lysate.
Lane 1: CENPJ transfected lysate(43.20 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00055835-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CENPJ (AAH24209.3, 1 a.a. approximately 372 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MRKLQKERKV FEKYTTAART FPDKKEREEI QTLKQQIADL REDLKRKETK WSSTHSRLRS QIQMLVRENT DLREEIKVME RFRLDAWKRA EAIESSLEVE KKDKLANTSV RFQNSQISSG TQVEKYKKNY LPMQGNPPRR SKSAPPRDLG NLDKGQAASP REPLEPLNFP DPEYKEEEED QDIQGEISHP DGKVEKVYKN GCRVILFPNG TRKEVSADGK TITVTFFNGD VKQVMPDQRV IYYYAAAQTT HTTYPEGLEV LHFSSGQIEK HYPDGRKEIT FPDQTVKNLF PDGQEESIFP DGTIVRVQRD GNKLIEFNNG QRELHTAQFK RREYPDGTVK TVYANGHQET KYRSGRIRVK DKEGNVLMDT EL
Target Information
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: CENP-J; Centromere protein J; Centrosomal P4.1-associated protein; Centrosome assembly and centriole elongation protein; LAG-3-associated protein; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; microcephaly
Gene Aliases: BM032; CENP-J; CENPJ; CPAP; LAP; LIP1; MCPH6; Sas-4; SASS4; SCKL4
UniProt ID: (Human) Q9C067
Entrez Gene ID: (Human) 55835
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support