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Immunogen sequence: SKSDQLLIVV SILEGRHFPK RPKHMLVVEA KFDGEQLATD PVDHTDQPEF ATELAWEIDR KALHQHRLQR TPIKLQCFAL DPVTSAKETI GYIVLDLRTA QETKQAPKWY QLLSNKYTKF KSEIQISIAL ETDTKPPVD
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 94%.
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: centrosomal protein 120kDa; Centrosomal protein of 120 kDa; Cep120; Coiled-coil domain-containing protein 100
Gene Aliases: CCDC100; CEP120; SRTD13
UniProt ID: (Human) Q8N960
Entrez Gene ID: (Human) 153241
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