Product References
Ependymal polarity defects coupled with disorganized ciliary beating drive abnormal cerebrospinal fluid flow and spine curvature in zebrafish.
PLoS biology
Xie H,Kang Y,Liu J,Huang M,Dai Z,Shi J,Wang S,Li L,Li Y,Zheng P,Sun Y,Han Q,Zhang J,Zhu Z,Xu L,Yelick PC,Cao M,Zhao C
Wed Mar 01 00:00:00 UTC 2023
SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.
Cell
Wu CT,Lidsky PV,Xiao Y,Cheng R,Lee IT,Nakayama T,Jiang S,He W,Demeter J,Knight MG,Turn RE,Rojas-Hernandez LS,Ye C,Chiem K,Shon J,Martinez-Sobrido L,Bertozzi CR,Nolan GP,Nayak JV,Milla C,Andino R,Jackson PK
Thu Jan 05 00:00:00 UTC 2023
CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis.
The Journal of cell biology
Lee M,Nagashima K,Yoon J,Sun J,Wang Z,Carpenter C,Lee HK,Hwang YS,Westlake CJ,Daar IO
Mon Jan 03 00:00:00 UTC 2022
Terminally differentiated osteoclasts organize centrosomes into large clusters for microtubule nucleation and bone resorption.
Molecular biology of the cell
Philip R,Fiorino C,Harrison RE
Fri Jul 01 00:00:00 UTC 2022
Arih2 regulates Hedgehog signaling through smoothened ubiquitylation and ER-associated degradation.
Journal of cell science
Lv B,Zhang XO,Pazour GJ
Mon Aug 15 00:00:00 UTC 2022
Multiple ciliary localization signals control INPP5E ciliary targeting.
eLife
Cilleros-Rodriguez D,Martin-Morales R,Barbeito P,Deb Roy A,Loukil A,Sierra-Rodero B,Herranz G,Pampliega O,Redrejo-Rodriguez M,Goetz SC,Izquierdo M,Inoue T,Garcia-Gonzalo FR
Mon Sep 05 00:00:00 UTC 2022
Evolutionary conservation of centriole rotational asymmetry in the human centrosome.
eLife
Gaudin N,Martin Gil P,Boumendjel M,Ershov D,Pioche-Durieu C,Bouix M,Delobelle Q,Maniscalco L,Phan TBN,Heyer V,Reina-San-Martin B,Azimzadeh J
Wed Mar 23 00:00:00 UTC 2022
ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis.
EMBO reports
Song T,Yang Y,Zhou P,Ran J,Zhang L,Wu X,Xie W,Zhong T,Liu H,Liu M,Li D,Zhao H,Zhou J
Wed May 04 00:00:00 UTC 2022
The evolutionary conserved proteins CEP90, FOPNL, and OFD1 recruit centriolar distal appendage proteins to initiate their assembly.
PLoS biology
Le Borgne P,Greibill L,Laporte MH,Lemullois M,Bouhouche K,Temagoult M,Rosnet O,Le Guennec M,Lignières L,Chevreux G,Koll F,Hamel V,Guichard P,Tassin AM
Thu Sep 01 00:00:00 UTC 2022
The mechanism of acentrosomal spindle assembly in human oocytes.
Science (New York, N.Y.)
Wu T,Dong J,Fu J,Kuang Y,Chen B,Gu H,Luo Y,Gu R,Zhang M,Li W,Dong X,Sun X,Sang Q,Wang L
Fri Nov 18 00:00:00 UTC 2022
Cell cycle arrest induced by trichoplein depletion is independent of cilia assembly.
Journal of cellular physiology
Huang M,Kong X,Tang Z,Lin Z,He R,Cao M,Zhang X
Wed Jun 01 00:00:00 UTC 2022
Human SFI1 and Centrin form a complex critical for centriole architecture and ciliogenesis.
The EMBO journal
Laporte MH,Bouhlel IB,Bertiaux E,Morrison CG,Giroud A,Borgers S,Azimzadeh J,Bornens M,Guichard P,Paoletti A,Hamel V
Wed Nov 02 00:00:00 UTC 2022
ANKRD26 recruits PIDD1 to centriolar distal appendages to activate the PIDDosome following centrosome amplification.
The EMBO journal
Evans LT,Anglen T,Scott P,Lukasik K,Loncarek J,Holland AJ
Mon Feb 15 00:00:00 UTC 2021
Analyzing Centrioles and Cilia by Expansion Microscopy.
Methods in molecular biology (Clifton, N.J.)
Kong D,Loncarek J
Tue Aug 24 00:00:00 UTC 2021
OCRL regulates lysosome positioning and mTORC1 activity through SSX2IP-mediated microtubule anchoring.
EMBO reports
Wang B,He W,Prosseda PP,Li L,Kowal TJ,Alvarado JA,Wang Q,Hu Y,Sun Y
Mon Jul 05 00:00:00 UTC 2021
Rab34 is necessary for early stages of intracellular ciliogenesis.
Current biology : CB
Stuck MW,Chong WM,Liao JC,Pazour GJ
Mon Jul 12 00:00:00 UTC 2021
TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity.
The Journal of cell biology
Meitinger F,Kong D,Ohta M,Desai A,Oegema K,Loncarek J
Mon Jul 05 00:00:00 UTC 2021
The SON RNA splicing factor is required for intracellular trafficking structures that promote centriole assembly and ciliogenesis.
Molecular biology of the cell
Stemm-Wolf AJ,O'Toole ET,Sheridan RM,Morgan JT,Pearson CG
Fri Oct 01 00:00:00 UTC 2021
Exocyst complex mediates recycling of internal cilia.
Current biology : CB
Rivera-Molina FE,Xi Z,Reales E,Wang B,Toomre D
Mon Dec 20 00:00:00 UTC 2021
Disrupted intraflagellar transport due to IFT74 variants causes Joubert syndrome.
Genetics in medicine : official journal of the American College of Medical Genetics
Luo M,Lin Z,Zhu T,Jin M,Meng D,He R,Cao Z,Shen Y,Lu C,Cai R,Zhao Y,Wang X,Li H,Wu S,Zou X,Luo G,Cao L,Huang M,Jiao H,Gao H,Sui R,Zhao C,Ma X,Cao M
Tue Jun 01 00:00:00 UTC 2021
Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development.
EMBO reports
Xiao C,Grzonka M,Meyer-Gerards C,Mack M,Figge R,Bazzi H
Wed Feb 03 00:00:00 UTC 2021
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Cell research
Liu M,Zhang W,Li M,Feng J,Kuang W,Chen X,Yang F,Sun Q,Xu Z,Hua J,Yang C,Liu W,Shu Q,Yang Y,Zhou T,Xie S
Mon Nov 01 00:00:00 UTC 2021
WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity.
eLife
Steib E,Laporte MH,Gambarotto D,Olieric N,Zheng C,Borgers S,Olieric V,Le Guennec M,Koll F,Tassin AM,Steinmetz MO,Guichard P,Hamel V
Fri Sep 18 00:00:00 UTC 2020
Prolonged mitosis results in structurally aberrant and over-elongated centrioles.
The Journal of cell biology
Kong D,Sahabandu N,Sullenberger C,Vásquez-Limeta A,Luvsanjav D,Lukasik K,Loncarek J
Mon Jun 01 00:00:00 UTC 2020
Ciliogenesis and Hedgehog signalling are suppressed downstream of KRAS during acinar-ductal metaplasia in mouse.
Disease models & mechanisms
Bangs FK,Miller P,O'Neill E
Thu Jul 30 00:00:00 UTC 2020
Cep128 associates with Odf2 to form the subdistal appendage of the centriole.
Genes to cells : devoted to molecular & cellular mechanisms
Kashihara H,Chiba S,Kanno SI,Suzuki K,Yano T,Tsukita S
Fri Mar 01 00:00:00 UTC 2019
Cep128 associates with Odf2 to form the subdistal appendage of the centriole.
Genes to cells : devoted to molecular & cellular mechanisms
Kashihara H,Chiba S,Kanno SI,Suzuki K,Yano T,Tsukita S
Fri Mar 01 00:00:00 UTC 2019
RABL2 positively controls localization of GPCRs in mammalian primary cilia.
Journal of cell science
Dateyama I,Sugihara Y,Chiba S,Ota R,Nakagawa R,Kobayashi T,Itoh H
Wed Jan 16 00:00:00 UTC 2019
Expansion microscopy for the analysis of centrioles and cilia.
Journal of microscopy
Sahabandu N,Kong D,Magidson V,Nanjundappa R,Sullenberger C,Mahjoub MR,Loncarek J
Sun Dec 01 00:00:00 UTC 2019
The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis.
The Journal of biological chemistry
Cuenca A,Insinna C,Zhao H,John P,Weiss MA,Lu Q,Walia V,Specht S,Manivannan S,Stauffer J,Peden AA,Westlake CJ
Fri Oct 18 00:00:00 UTC 2019
Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation.
EMBO reports
Odabasi E,Gul S,Kavakli IH,Firat-Karalar EN
Sat Jun 01 00:00:00 UTC 2019
NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.
Scientific reports
Martin-Hurtado A,Martin-Morales R,Robledinos-Antón N,Blanco R,Palacios-Blanco I,Lastres-Becker I,Cuadrado A,Garcia-Gonzalo FR
Wed Sep 25 00:00:00 UTC 2019
High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy.
Nature communications
Bowler M,Kong D,Sun S,Nanjundappa R,Evans L,Farmer V,Holland A,Mahjoub MR,Sui H,Loncarek J
Fri Mar 01 00:00:00 UTC 2019
Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.
EMBO reports
Jeong AL,Ka HI,Han S,Lee S,Lee EW,Soh SJ,Joo HJ,Sumiyasuren B,Park JY,Lim JS,Park JH,Lee MS,Yang Y
Tue May 01 00:00:00 UTC 2018
Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.
EMBO reports
Jeong AL,Ka HI,Han S,Lee S,Lee EW,Soh SJ,Joo HJ,Sumiyasuren B,Park JY,Lim JS,Park JH,Lee MS,Yang Y
Tue May 01 00:00:00 UTC 2018
Glucose deprivation induces primary cilium formation through mTORC1 inactivation.
Journal of cell science
Takahashi K,Nagai T,Chiba S,Nakayama K,Mizuno K
Mon Jan 08 00:00:00 UTC 2018
Glucose deprivation induces primary cilium formation through mTORC1 inactivation.
Journal of cell science
Takahashi K,Nagai T,Chiba S,Nakayama K,Mizuno K
Mon Jan 08 00:00:00 UTC 2018
VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis.
Scientific reports
Ott C,Nachmias D,Adar S,Jarnik M,Sherman S,Birnbaum RY,Lippincott-Schwartz J,Elia N
Tue Feb 20 00:00:00 UTC 2018
VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis.
Scientific reports
Ott C,Nachmias D,Adar S,Jarnik M,Sherman S,Birnbaum RY,Lippincott-Schwartz J,Elia N
Tue Feb 20 00:00:00 UTC 2018
M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole.
Nature communications
Huang N,Zhang D,Li F,Chai P,Wang S,Teng J,Chen J
Tue Oct 30 00:00:00 UTC 2018
The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.
Developmental cell
Kanie T,Abbott KL,Mooney NA,Plowey ED,Demeter J,Jackson PK
Mon Jul 10 00:00:00 UTC 2017
Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis.
Current biology : CB
Hamel V,Steib E,Hamelin R,Armand F,Borgers S,Flückiger I,Busso C,Olieric N,Sorzano COS,Steinmetz MO,Guichard P,Gönczy P
Mon Aug 21 00:00:00 UTC 2017
Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis.
Current biology : CB
Hamel V,Steib E,Hamelin R,Armand F,Borgers S,Flückiger I,Busso C,Olieric N,Sorzano COS,Steinmetz MO,Guichard P,Gönczy P
Mon Aug 21 00:00:00 UTC 2017
DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6.
Nature communications
Xu X,Huang S,Zhang B,Huang F,Chi W,Fu J,Wang G,Li S,Jiang Q,Zhang C
Thu Apr 27 00:00:00 UTC 2017
DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6.
Nature communications
Xu X,Huang S,Zhang B,Huang F,Chi W,Fu J,Wang G,Li S,Jiang Q,Zhang C
Thu Apr 27 00:00:00 UTC 2017
Genetic link between renal birth defects and congenital heart disease.
Nature communications
San Agustin JT,Klena N,Granath K,Panigrahy A,Stewart E,Devine W,Strittmatter L,Jonassen JA,Liu X,Lo CW,Pazour GJ
Tue Mar 22 00:00:00 UTC 2016
Genetic link between renal birth defects and congenital heart disease.
Nature communications
San Agustin JT,Klena N,Granath K,Panigrahy A,Stewart E,Devine W,Strittmatter L,Jonassen JA,Liu X,Lo CW,Pazour GJ
Tue Mar 22 00:00:00 UTC 2016
TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23).
eLife
Stephen LA,Tawamie H,Davis GM,Tebbe L,Nürnberg P,Nürnberg G,Thiele H,Thoenes M,Boltshauser E,Uebe S,Rompel O,Reis A,Ekici AB,McTeir L,Fraser AM,Hall EA,Mill P,Daudet N,Cross C,Wolfrum U,Jamra RA,Davey MG,Bolz HJ
Sat Sep 19 00:00:00 UTC 2015
TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23).
eLife
Stephen LA,Tawamie H,Davis GM,Tebbe L,Nürnberg P,Nürnberg G,Thiele H,Thoenes M,Boltshauser E,Uebe S,Rompel O,Reis A,Ekici AB,McTeir L,Fraser AM,Hall EA,Mill P,Daudet N,Cross C,Wolfrum U,Jamra RA,Davey MG,Bolz HJ
Sat Sep 19 00:00:00 UTC 2015
