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CERK has 2 isoforms with the molecular weight of 60 and 38 kDa.
Immunogen sequence: AVLVPSSLR IGIIPAGSTD CVCYSTVGTS DAETSALHIV VGDSLAMDVS SVHHNSTLLR YSVSLLGYGF YGDIIKDSEK KRWLGLARYD FSGLKTFLSH HCYEGTVSFL PAQHTVGSPR DRKPCRAGCF VCRQSKQQLE EEQKKALYGL EAAEDVEEWQ VVCGKFLAIN ATNMSCACRR SPRGLSPAAH LGDGSSDLIL IRKCSRFNFL RFLIRHTNQQ DQFDFTFVEV YRVKKFQFTS KHMEDEDSDL KEGGKKRFGH ICSSHPSCCC TVSNSSWNCD GEVLHSPAIE VRVHCQLVRL FARGIEENPK PDSHS (224-537 aa encoded by BC126940)
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acylsphingosine kinase; Ceramide kinase; CERK antibody; hCERK; Lipid kinase 4; lipid kinase LK4; LK4; mCERK
Gene Aliases: AI848610; CERK; D330016D08Rik; dA59H18.2; dA59H18.3; hCERK; KIAA1646; LK4; mKIAA1646
UniProt ID: (Human) Q8TCT0, (Mouse) Q8K4Q7
Entrez Gene ID: (Human) 64781, (Mouse) 223753
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