Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Sequence of this protein is as follows: MTAQSRSPTT PTFPGPSQRT PLTPCPVQTP RLGKALIHCW TDPGQPLGEQ QRVRRQRTET SEPTMRLHRL RARLSAVACG LLLLLVRGQG QDSASPIRTT HTGQVLGSLV HVKGANAGVQ TFLGIPFAKP PLGPLRFAPP EPPESWSGVR DGTTHPAMCL QDLTAVESEF LSQFNMTFPS DSMSEDCLYL SIYTPAHSHE GSNLPVMVWI HGGALVFGMA SLYDGSMLAA LENVVVVIIQ YRLGVLGFFS TGDKHATGNW GYLDQVAALR WVQQNIAHFG GNPDRVTIFG ESAGGTSVSS LVVSPISQGL FHGAIMESGV ALLPGLIASS ADVISTVVAN LSACDQVDSE ALVGCLRGKS KEEILAINKP FKMIPGVVDG VFLPRHPQEL LASADFQPVP SIVGVNNNEF GWLIPKVMRI YDTQKEMDRE ASQAALQKML TLLMLPPTFG DLLREEYIGD NGDPQTLQAQ FQEMMADSMF VIPALQVAHF QCSRAPVYFY EFQHQPSWLK NIRPPHMKAD HGDELPFVFR SFFGGNYIKF TEEEEQLSRK MMKYWANFAR NGNPNGEGLP HWPLFDQEEQ YLQLNLQPAV GRALKAHRLQ FWKKALPQKI QELEEPEERH TEL
CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Carboxylesterase 2; carboxylesterase 2 (intestine, liver); CE-2; CES-2; Cocaine esterase; hCE-2; intestinal carboxylesterase; liver carboxylesterase-2; Methylumbelliferyl-acetate deacetylase 2; P iCE
Gene Aliases: CE-2; CES2; CES2A1; ICE; PCE-2
UniProt ID: (Human) O00748
Entrez Gene ID: (Human) 8824
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