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Invitrogen
CF106 Polyclonal Antibody
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Product Details
PA5-56950
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CF106. Recombinant protein control fragment (Product #RP-104251).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2639715
Product Specific Information
Immunogen sequence: DVTIGEGESI PPDTQFVKTW RIQNSGAEAW PPGVCLKYVG GDQFGHVNMV MVRSLEPQEI ADVSVQMCSP SR
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Inflammation and lipid regulator with UBA-like and NBR1-like domains protein; Protein ILRUN
Gene Aliases: C6orf106; dJ391O22.4; FP852; ILRUN
UniProt ID: (Human) Q9H6K1
Entrez Gene ID: (Human) 64771
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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