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Sequence of this protein is as follows: VGDIGDTVED PYTSFVKLLP LNDCRYALYD ATYETKESKK EDLVFIFWAP ESAPLKSKMI YASSKDAIKK KFTGIKHEWQ VNGLDDIKDR STLGEKLGGN VVVSLEGKPL
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COF2; cofilin 2 (muscle); Cofilin, muscle isoform; Cofilin-2; HGNC:1875; nemaline myopathy type 7
Gene Aliases: CFL2; NEM7
UniProt ID: (Human) Q9Y281
Entrez Gene ID: (Human) 1073
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