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Invitrogen
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Immunogen sequence: LPKSALFSES QKAVELGDEL QIDAIDDQKC DILVQEELLA SPKKLLEDTL FPSSKKLKKD NQESSDAELS SSEYIKTDLD AMDIKGQESS SDQEQVDVES IDFSKENKMD MTSPEQSRNV LQFTEEKEAF ISEEEIAKYM KRGKGKYYCK ICCCRAMKKG AVLHHLVNKH NVHSPYKCTI CGKAFLLESL LKNHVAAHGQ SLLKCPRCNF ESNFPRGFKK HLTHCQSRHN EEANKKLMEA LEPPLEEQQI; Positive Samples: U-87MG, A-431, Jurkat ; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, kinetochore, spindle
Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chromosome alignment-maintaining phosphoprotein 1; Zinc finger protein 828
Gene Aliases: C13orf8; CAMP; CHAMP; CHAMP1; KIAA1802; MRD40; ZNF828
UniProt ID: (Human) Q96JM3
Entrez Gene ID: (Human) 283489
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