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Invitrogen
CHMP1B Polyclonal Antibody
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Product Details
PA5-44773
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human CHMP1B (aa 35-84).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607095
Product Specific Information
Peptide sequence: KIKKAIQKGN MEVARIHAEN AIRQKNQAVN FLRMSARVDA VAARVQTAVT
Sequence homology: Cow: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Target Information
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Charged multivesicular body protein 1b; CHMP1.5; CHMP1b; chromatin modifying protein 1B; Chromatin-modifying protein 1b; vacuolar protein sorting 46-2; Vacuolar protein sorting-associated protein 46-2; Vps46-2
Gene Aliases: C10orf2; C18-ORF2; C18orf2; CHMP1.5; CHMP1B; hVps46-2; Vps46-2; Vps46B
UniProt ID: (Human) Q7LBR1
Entrez Gene ID: (Human) 57132
cell separation after cytokinesis
nucleus organization
vacuolar transport
mitotic metaphase plate congression
regulation of centrosome duplication
protein transport
multivesicular body assembly
viral budding via host ESCRT complex
establishment of protein localization
cell division
regulation of mitotic spindle assembly
ESCRT III complex disassembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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