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Proteintech
CHMP6 Polyclonal Antibody
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Product Details
16278-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHMP6 Fusion Protein Ag9357 (1-201 aa encoded by BC010108)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGNLFGRKK QSRVTEQDKA ILQLKQQRDK LRQYQKRIAQ QLERERALAR QLLRDGRKER AKLLLKKKRY QEQLLDRTEN QISSLEAMVQ SIEFTQIEMK VMEGLQFGNE CLNKMHQVMS IEEVERILDE TQEAVEYQRQ IDELLAGSFT QEDEDAILEE LSAITQEQIE LPEVPSEPLP EKIPENVPVK ARPRQAELVA AS (1-201 aa encoded by BC010108)
Target Information
CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Charged multivesicular body protein 6; chromatin modifying protein 6; Chromatin-modifying protein 6; hVps20; novel SNF7 protein; Vacuolar protein sorting-associated protein 20; Vps20
Gene Aliases: 2400004G01Rik; CHMP6; RGD1565325; VPS20
UniProt ID: (Human) Q96FZ7, (Mouse) P0C0A3
Entrez Gene ID: (Human) 79643, (Mouse) 208092, (Rat) 287873
cell separation after cytokinesis
transport
nucleus organization
vacuolar transport
mitotic metaphase plate congression
protein transport
viral budding via host ESCRT complex
autophagy
endosomal transport
viral life cycle
multivesicular body assembly
regulation of exosomal secretion
ESCRT III complex assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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