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Proteintech
CHPF-N terminal Polyclonal Antibody
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Product Details
15801-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHPF-N terminal Fusion Protein Ag8523 (1-368 aa encoded by BC008878)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GSPRCPLRG ADRADVADVL GTALEELNRR YHPALRLQKQ QLVNGYRRFD PARGMEYTLD LQLEALTPQG GRRPLTRRVQ LLRPLSRVEI LPVPYVTEAS RLTVLLPLAA AERDLAPGFL EAFATAALEP GDAAAALTLL LLYEPRQAQR VAHADVFAPV KAHVAELERR FPGARVPWLS VQTAAPSPLR LMDLLSKKHP LDTLFLLAGP DTVLTPDFLN RCRMHAISGW QAFFPMHFQA FHPAVAPPQG PGPPELGRDT GRFDRQAASE ACFYNSDYVA ARGRLAAASE QEEELLESLD VYELFLHFSS LHVLRAVEPA LLQRYRAQTC SARLSEDLYH RCLQSVLEGL GSRTQLAMLL FEQEQGNST (1-368 aa encoded by BC008878 )
Target Information
Chondroitin sulfate synthases (CHSYs) synthesize chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to various of core protein families and regulate many biologic processes, including extracellular matrix deposition, cell proliferation and recognition, and morphogenesis. The CHSY family includes CHSY1, CHSY2 and CHSY3. CHSY1 and CHSY3 display both glucuronyltransferase and N-acetylgalactosaminyltransferase activities, while CHSY2 is required for chondroitin polymerizing activity. CHSY2 localizes to the Golgi apparatus and is expressed ubiquitously, with highest expression observed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chondroitin glucuronyltransferase 2; Chondroitin sulfate synthase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II; N-acetylgalactosaminyltransferase 2
Gene Aliases: 1700028N03Rik; AI414328; CHPF; CHSY2; CSS2; D1Bwg1363e; UNQ651/PRO1281
UniProt ID: (Human) Q8IZ52, (Mouse) Q6IQX7
Entrez Gene ID: (Human) 79586, (Mouse) 74241, (Rat) 316533
metal ion binding
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity
protein binding
acetylgalactosaminyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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