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Product Details
PA5-33433
Product Specifications
Species Reactivity
Bovine,
Horse,
Guinea pig,
Hamster,
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human CHRM4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550813
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Mouse, Rat, Bovine, Hamster, Horse, Pig, Guinea pig (100%) Dog, Elephant, Panda (95%) Bat (90%).
Target Information
Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor, muscarinic 4; AChR M4; cholinergic receptor; cholinergic receptor, muscarin 4; cholinergic receptor, muscarinic 4; Mm4 mAChR; muscarinic acetylcholine receptor 4; Muscarinic acetylcholine receptor M4; muscarinic receptor, M4 subtype
Gene Aliases: BOS_15127; Chrm-4; CHRM4; HM4; I79_002865; M4; M4R
UniProt ID: (Human) P08173, (Mouse) P32211, (Rat) P08485
Entrez Gene ID: (Bovine) 512928, (Human) 1132, (Mouse) 12672, (Rat) 25111, (Chinese hamster) 100752496
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
chemical synaptic transmission
synaptic transmission, cholinergic
sensory perception of chemical stimulus
regulation of locomotion
positive regulation of GTPase activity
G-protein coupled acetylcholine receptor signaling pathway
response to organic substance
cell surface receptor signaling pathway
cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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