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Product Details
PA5-51283
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide of human CHRM5
Conjugate
Form
Liquid
Concentration
1.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2636730
Product Specific Information
The antibody detects endogenous levels of total CHRM5 protein.
Target Information
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor, muscarinic 5; cholinergic receptor; cholinergic receptor, muscarinic 5; muscarinic acetylcholine receptor 5; Muscarinic acetylcholine receptor M5
Gene Aliases: AChR-M5; Chrm-5; CHRM5; HM5; m5; M5R
UniProt ID: (Human) P08912, (Rat) P08911, (Mouse) Q920H4
Entrez Gene ID: (Human) 1133, (Rat) 53949, (Mouse) 213788
gastric acid secretion
G-protein coupled acetylcholine receptor signaling pathway
dopamine transport
transmission of nerve impulse
regulation of phosphatidylinositol dephosphorylation
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
synaptic transmission, cholinergic
cell proliferation
signal transduction
G-protein coupled receptor signaling pathway
chemical synaptic transmission
sensory perception of chemical stimulus
chloride transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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